Zobrazeno 1 - 10
of 339
pro vyhledávání: '"Liren Zhang"'
Autor:
Ruizhi Zhang, Jingjing Dai, Feifan Yao, Suiqing Zhou, Wei Huang, Jiali Xu, Kai Yu, Yining Chen, Boqiang Fan, Liren Zhang, Jing Xu, Qing Li
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109821- (2024)
Summary: The cyclic AMP-responsive element-binding protein (CREB)-regulated transcription coactivator 2 (CRTC2) is a crucial regulator of hepatic lipid metabolism and gluconeogenesis and correlates with tumorigenesis. However, the mechanism through w
Externí odkaz:
https://doaj.org/article/8a886f1deb8943568b9dd6f6d0be7c7b
Autor:
Jingjing Dai, Liren Zhang, Ruizhi Zhang, Jing Ge, Feifan Yao, Suiqing Zhou, Jiali Xu, Kai Yu, Jing Xu, Longfeng Jiang, Ke Jin, Xinzheng Dai, Jun Li, Qing Li
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 3, Pp 399-421 (2024)
Background & Aims: Metabolic dysfunction–associated steatohepatitis (MASH) is a common chronic liver disease worldwide. No effective pharmacologic therapies for MASH have been developed; to develop such promising drugs, the underlying mechanisms re
Externí odkaz:
https://doaj.org/article/a13a428fe0854d8e8198a0b371ffe89a
Autor:
Qing Li, Liren Zhang, Wenhua You, Jiali Xu, Jingjing Dai, Dongxu Hua, Ruizhi Zhang, Feifan Yao, Suiqing Zhou, Wei Huang, Yongjiu Dai, Yu Zhang, Tasiken Baheti, Xiaofeng Qian, Liyong Pu, Jing Xu, Yongxiang Xia, Chuanyong Zhang, Jinhai Tang, Xuehao Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Members of the PRDI-BF1 and RIZ homology domain (PRDM) family have been involved in the regulation of several pathological conditions, including cancer. Here the authors show that PRDM1/BLIMP1 promotes immune evasion by regulating PD-L1 expression in
Externí odkaz:
https://doaj.org/article/fb2dd84c298849c9b30b8a103d084836
Publikováno v:
Journal of Materials Research and Technology, Vol 21, Iss , Pp 3594-3603 (2022)
Transparent wood is a promising material with many advantages, including high optical transmittance, adjustable optical haze, and excellent mechanical properties. However, the manufacture of transparent wood always requires polymer filling, which aff
Externí odkaz:
https://doaj.org/article/0f23fa1e0d9148c78c49fe1eb9586c80
Autor:
Shangqin Long, Liren Zhang, Xiaodong Li, Yongjie He, Xin Wen, Nannan Xu, Xiaoqing Li, Jingmin Wang
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
ObjectivesPositive antiphospholipid antibodies (aPLs) and chronic hypertension (CH) in pregnancy are important causes of maternal and neonatal morbidity and mortality. However, there are no relevant studies on the treatment of aPL-positive pregnant w
Externí odkaz:
https://doaj.org/article/2ad354ad17a346f79fe758d5aa6cbe19
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 28 (2022)
Acute ischemic stroke (AIS), characterized by high morbidity and mortality, has imposed a considerable burden on society. Despite rapid development in the treatment of AIS, there is still a high risk of recurrence. Furthermore, there is a time delay
Externí odkaz:
https://doaj.org/article/7397aebcd7914070b8934690facef055
Autor:
Xiang Qi, Zhide Zhu, Yuhan Wang, Zhihao Wen, Zhixiong Jiang, Liren Zhang, Yan Pang, Jianqi Lu
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Heart failure is one of the major public health problems in the world. In recent years, more and more attention has been paid to the relationship between heart failure and mitochondrial function. In the past 2 decades, a growing number of research pa
Externí odkaz:
https://doaj.org/article/1eac5e8aa6df4b2a97929304e2ab4ca3
Autor:
Wenjun Ren, Yixiao Yuan, Xi Chen, Haoqing Zhai, Yin An, Lin Tang, Juan Wang, Dahang Zhang, Liren Zhang, Wanli Cheng, Xin Wang, Lincan Duan, Luciano Mutti, Bin Han, Ping Wang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Lung cancer is the leading cause of cancer-related death worldwide. Therapies for lung cancer have relatively poor outcomes and need to be improved. Lung cancer immune cell infiltration associated RNA (LCIIAR) is a long noncoding RNA (lncRNA), which
Externí odkaz:
https://doaj.org/article/de62cce578e547518d640d4eb7fa571e
Autor:
Qing Li, Yong Ni, Liren Zhang, Runqiu Jiang, Jing Xu, Hong Yang, Yuanchang Hu, Jiannan Qiu, Liyong Pu, Jinhai Tang, Xuehao Wang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-13 (2021)
Abstract N6-methyladenosine (m6A), and its reader protein YTHDF1, play a pivotal role in human tumorigenesis by affecting nearly every stage of RNA metabolism. Autophagy activation is one of the ways by which cancer cells survive hypoxia. However, th
Externí odkaz:
https://doaj.org/article/73b29da9a71b4a0dbaa1873c2fa4c763
Publikováno v:
Frontiers in Neurology, Vol 12 (2022)
Background and Purpose: Non-convulsive status epilepticus (NCSE) is common in patients with disorders of consciousness and can cause secondary brain injury. Our study aimed to explore the determinants and prognostic significance of NCSE in stroke pat
Externí odkaz:
https://doaj.org/article/f9b58475f9ce43638dc73d622737b314