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A role for HB-EGF/EGFR and MAPK signaling in the development of intestinal serrated polyps in mice

Autor: Bongers, G.M., Muniz, L. R., Pacer, M., Thirunarayanan, N., Smit, M.J., Reddy, E.P., Mayer, L., Furtado, G.C., Harpaz, N., Lira, SA

Publikováno v: Gastroenterology, 143, 730-740. W.B. Saunders Ltd
Bongers, G M, Muniz, L R, Pacer, M, Thirunarayanan, N, Smit, M J, Reddy, E P, Mayer, L, Furtado, G C, Harpaz, N & Lira, SA 2012, ' A role for HB-EGF/EGFR and MAPK signaling in the development of intestinal serrated polyps in mice ', Gastroenterology, vol. 143, pp. 730-740 . https://doi.org/10.1053/j.gastro.2012.05.034

BACKGROUND & AIMS: Epithelial cancers can be initiated by activating mutations in components of the mitogen-activated protein kinase signaling pathway such as v-raf murine sarcoma viral oncogene homolog B1 (BRAF), v-Ki-ras2 Kirsten rat sarcoma viral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::42b3f81230833c8f2dff3b5e724933ef
https://research.vu.nl/en/publications/7beb0165-dd3d-4c0a-865e-5c9c1e0378c5

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Chemokine Receptors as Drug Targets

Autor: Smit, M.J., Lira, SA, Leurs, R., Raimund Mannhold, R., Hugo Kubinyi, H., Gerd Folkers, G.

Publikováno v: Methods and Principles in Medicinal Chemistry

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::593f2206a62573a1a35dd303b65869e2
https://research.vu.nl/en/publications/638c2e0c-6102-4d3d-904b-ec36d416fdea

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Constitutively Active Viral Chemokine Receptors: Tools for Immune Subversion and Pathogenesis

Autor: Maussang Detaille, D.A.B., Bongers, G.M., Lira, SA, Smit, M.J.

Publikováno v: Maussang Detaille, D A B, Bongers, G M, Lira, SA & Smit, M J 2010, Constitutively Active Viral Chemokine Receptors: Tools for Immune Subversion and Pathogenesis . in M J Martine Smit, S A Sergio Lira & R Rob Leurs (eds), Chemokine Receptors as Drug Targets . Wiley-VCH, Germany, pp. 177-189 .

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::db630693d4c64f54c298e0fa1152993c
https://research.vu.nl/en/publications/375e483d-74da-4c4a-8f6c-8abd887a595f

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Aberrant in vivo T helper type 2 cell response and impaired eosinophil recruitment in CC chemokine receptor 8 knockout mice

Autor: Chensue, SW, Lukacs, NW, Yang, TY, Shang, X, Frait, KA, Kunkel, SL, Kung, T, Wiekowski, MT, Hedrick, JA, Cook, DN, Zingoni, A, Narula, SK, Zlotnik, A, Barrat, FJ, O'Garra, A, Napolitano, M, Lira, SA

Publikováno v: Chensue, SW; Lukacs, NW; Yang, TY; Shang, X; Frait, KA; Kunkel, SL; et al.(2001). Aberrant in vivo T helper type 2 cell response and impaired eosinophil recruitment in CC chemokine receptor 8 knockout mice. Journal of Experimental Medicine, 193(5), 573-584. doi: 10.1084/jem.193.5.573. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/0zn146cz

Chemokine receptors transduce signals important for the function and trafficking of leukocytes. Recently, it has been shown that CC chemokine receptor (CCR)8 is selectively expressed by Th2 subsets, but its functional relevance is unclear. To address

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::4405e3ed37bf5edecfd750259188d74f
http://www.escholarship.org/uc/item/0zn146cz

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