Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Liqiong Gui"'
Publikováno v:
Cell Transplantation, Vol 27 (2018)
Objective: Invasive coronary interventions can fail due to intimal hyperplasia and restenosis. Endothelial cell (EC) seeding to the vessel lumen, accelerating re-endothelialization, or local release of mTOR pathway inhibitors have helped reduce intim
Externí odkaz:
https://doaj.org/article/40ba98cd4c5c4ab4841c291e2f2df3ab
Autor:
Thomas H. Petersen, Thomas Hitchcock, Akihito Muto, Elizabeth A. Calle, Liping Zhao, Zhaodi Gong, Liqiong Gui, Alan Dardik, Dawn E. Bowles, Christopher M. Counter, Laura E. Niklason M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 19 (2010)
While advances in regenerative medicine and vascular tissue engineering have been substantial in recent years, important stumbling blocks remain. In particular, the limited life span of differentiated cells that are harvested from elderly human donor
Externí odkaz:
https://doaj.org/article/59b01061342449c08f4948c12d78e87d
Autor:
Muhammad Riaz, Mehmet H. Kural, Christopher W. Anderson, Yibing Qyang, Yan Huang, Jiesi Luo, Jin-Kyu Park, Subhash K. Das, Colleen A. Lopez, Liqiong Gui, Ronald Ng, Laura E. Niklason, Juan Wang, Stuart G. Campbell, Lorenzo R. Sewanan
Publikováno v:
Acta Biomater
Single ventricle heart defects (SVDs) are congenital disorders that result in a variety of complications, including increased ventricular mechanical strain and mixing of oxygenated and deoxygenated blood, leading to heart failure without surgical int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1671a45742a3aca40acfc3c21c7573dc
https://doi.org/10.1016/j.actbio.2019.10.019
https://doi.org/10.1016/j.actbio.2019.10.019
Autor:
Katherine L. Leiby, Juan Wang, Mehmet H. Kural, George Tellides, Liqiong Gui, W. Mark Saltzman, Guangxin Li, Elias Quijano, Yifan Yuan, Laura E. Niklason
Publikováno v:
Biomaterials
Metallic stents cause vascular wall damage with subsequent smooth muscle cell (SMC) proliferation, neointimal hyperplasia, and treatment failure. To combat in-stent restenosis, drug-eluting stents (DES) delivering mTOR inhibitors such as sirolimus or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab2cca06d913366ab444a25e9d1b6475
https://doi.org/10.1016/j.biomaterials.2019.05.011
https://doi.org/10.1016/j.biomaterials.2019.05.011
Publikováno v:
Cell Transplantation
Cell Transplantation, Vol 27 (2018)
Cell Transplantation, Vol 27 (2018)
Objective: Invasive coronary interventions can fail due to intimal hyperplasia and restenosis. Endothelial cell (EC) seeding to the vessel lumen, accelerating re-endothelialization, or local release of mTOR pathway inhibitors have helped reduce intim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf97e4e9463c8248b301890dfe1cbd2
https://doi.org/10.1177/0963689718792201
https://doi.org/10.1177/0963689718792201
Autor:
Jiesi Luo, Stuart G. Campbell, Yibing Qyang, David H. Sachs, Alan Dardik, Marsha W. Rolle, Liqiong Gui, Peining Li, George Tellides, Xiaoqiang Cong, Xia Li, Darrell N. Kotton, Laura E. Niklason, Lingfeng Qin, Jordan S. Pober, Matthew W. Ellis, Jonas Schwan, Yongming Ren, Mehmet H. Kural, Guangxin Li, Robert J. Hawley, Oscar Bartulos
Publikováno v:
Biomaterials. 147:116-132
Development of autologous tissue-engineered vascular constructs using vascular smooth muscle cells (VSMCs) derived from human induced pluripotent stem cells (iPSCs) holds great potential in treating patients with vascular disease. However, preclinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d246f7640feec63c6257bd7de58b74cc
https://doi.org/10.1016/j.biomaterials.2017.09.019
https://doi.org/10.1016/j.biomaterials.2017.09.019
Autor:
Liqiong Gui, Elias Quijano, Juan Wang, W. Mark Saltzman, Geroge Tellides, Katherine L. Leiby, Laura E. Niklason, Yifan Yuan, Guangxin Li, Mehmet H. Kural
Publikováno v:
Circulation Research. 125
To restore blood flow in stenotic vessels such as coronary arteries, metallic vascular stents are often used. However, stent deployment under high pressure leads to vascular wall and smooth muscle (SMC) damage, with compensatory thrombosis, inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc44086a0d10f8c7617bd07f1fd782a6
https://doi.org/10.1161/res.125.suppl_1.755
https://doi.org/10.1161/res.125.suppl_1.755
Autor:
Alan Dardik, Takuya Hashimoto, Biraja C. Dash, Yibing Qyang, George Tellides, Jiesi Luo, Laura E. Niklason, Lingfeng Qin, Hongwei Wu, Liping Zhao, Kota Yamamoto, Liqiong Gui
Publikováno v:
Biomaterials. 102:120-129
Derivation of functional vascular smooth muscle cells (VSMCs) from human induced pluripotent stem cells (hiPSCs) to generate tissue-engineered blood vessels (TEBVs) holds great potential in treating patients with vascular diseases. Herein, hiPSCs wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31741a18c599285b11798c13bf6489e5
https://doi.org/10.1016/j.biomaterials.2016.06.010
https://doi.org/10.1016/j.biomaterials.2016.06.010
Autor:
Themis R. Kyriakides, Lise Tchouta, Amanda Weyers, John M. Tarbell, Wei Wu, Robert J. Linhardt, Sumati Sundaram, David Slattery, Liqiong Gui, Charles T. Tuggle, Chao Cai, Laura E. Niklason, Sashka Dimitrievska, Tylee Lin, Jenna L. Balestrini
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36:1847-1853
Objective— It is widely accepted that the presence of a glycosaminoglycan-rich glycocalyx is essential for endothelialized vasculature health; in fact, a damaged or impaired glycocalyx has been demonstrated in many vascular diseases. Currently, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea35356954c7ffbe93a47caed9acb9bf
https://doi.org/10.1161/atvbaha.116.308023
https://doi.org/10.1161/atvbaha.116.308023
Autor:
Mehmet H. Kural, Yibing Qyang, Muhammad Riaz, Guangxin Li, Liqiong Gui, Jiesi Luo, Laura E. Niklason, Stuart G. Campbell, Liping Zhao, Colleen A. Lopez, Alan Dardik, Lingfeng Qin, Yifan Yuan, Shang Min Zhang, George Tellides, J. Alexander Clark, Xiaoqiang Cong, Juan Wang, Shun Ono, Matthew W. Ellis, Yan Huang, Akitsu Hotta
Publikováno v:
Cell Stem Cell. 26:251-261.e8
Summary Vascular smooth muscle cells (VSMCs) can be derived in large numbers from human induced pluripotent stem cells (hiPSCs) for producing tissue-engineered vascular grafts (TEVGs). However, hiPSC-derived TEVGs are hampered by low mechanical stren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3390fdf913a75f41214f0f1a03faaf8a
https://doi.org/10.1016/j.stem.2019.12.012
https://doi.org/10.1016/j.stem.2019.12.012