Calcium-Selective Ion Channel, CaT1, Is Apically Localized in Gastrointestinal Tract Epithelia and Is Aberrantly Expressed in Human Malignancies

Autor: Matthias A. Hediger, Ji-Bin Peng, Liyan Zhuang, Liqiang Tou, Hitomi Takanaga, Michael R. Freeman, Rosalyn M. Adam

Publikováno v: Laboratory Investigation. 82:1755-1764

CaT1 is a highly selective calcium entry channel that has been proposed to be responsible for apical calcium entry in the vitamin D-regulated transcellular pathway of Ca(2+) absorption; however, the lack of a CaT1 antibody suitable for immunohistoche

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a30ab5e0c7e45bf712df82ed39f443c1
https://doi.org/10.1097/01.lab.0000043910.41414.e7

Backbone Dynamics of Human Parathyroid Hormone (1-34): Flexibility of the Central Region under Different Environmental Conditions

Autor: Michael Chorev, Stefano Mammi, Joseph M. Alexander, Michele Scian, Massimo Bellanda, Liqiang Tou, Massimiliano Marin, Evaristo Peggion, Michael Rosenblatt

Publikováno v: Biopolymers
84 (2006): 147–160.
info:cnr-pdr/source/autori:M. Scian, M. Marin, M. Bellanda, L. Tou, J.M. Alexander, M. Rosenblatt, M. Chorev, E. Peggion, and S. Mammi/titolo:Backbone Dynamics of Human Parathyroid Hormone (1-34): Flexibility of the Central Region under Different Environmental Conditions/doi:/rivista:Biopolymers (Print)/anno:2006/pagina_da:147/pagina_a:160/intervallo_pagine:147–160/volume:84

The presence of a stable tertiary structure in the bioactive N-terminal portion of parathyroid hormone (PTH), a major hormone in the maintenance of extracellular calcium homeostasis, is still debated. In this work, 15N relaxation parameters of the 33

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da68d669a8b173adc40300e23ba33d4
http://www.cnr.it/prodotto/i/15197

Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF)

Autor: Ramesh A. Shivdasani, Alexander J. Lazar, Jun-ichi Sawada, Li Cai, Jessica A. Williamson, Allen D. Everett, Mark Redston, Liqiang Tou, Edward A. Fox, Yoshihiro Nakatani, Jonathan N. Glickman, Maina Lepourcelet

Publikováno v: Development (Cambridge, England). 132(2)

The vertebrate intestine is a model for investigating inductive cellular interactions and the roles of epithelial stem cells in tissue regeneration,and for understanding parallels between development and cancer. We have used serial analysis of gene e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a022f6e130a7e7ed1e95ce8b5fa6fd
https://pubmed.ncbi.nlm.nih.gov/15604097

Abstract C82: Identification and preclinical characterization of inhibitors of the ubiquitin-activating enzymes UBA1 and UBA6

Autor: Paul E. Fleming, James M. Gavin, Yu Yang, Marc Hyer, Petter Veiby, Michael Milhollen, Peter G. Smith, Tary Traore, Sai M. Pulukuri, Jeff Ciavarri, Mark Manfredi, Darshan S. Sappal, Neil Bence, James E. Brownell, Kara Hoar, Jessica Huck, Christopher F. Claiborne, Lawrence Dick, Derek Liqiang Tou

Publikováno v: Molecular Cancer Therapeutics. 10:C82-C82

Millennium Pharmaceuticals, Inc. is dedicated to the discovery and development of novel oncology therapeutics in the area of protein homeostasis. Here we report the identification and characterization of compounds that target the ubiquitin activating

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf46ab98094e19a549c2b41c70c866cd
https://doi.org/10.1158/1535-7163.targ-11-c82

Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF).

Autor: Lepourcelet, Maina, Liqiang Tou, Li Cai, Sawada, Jun-ichi, Lazar, Alexander J. F., Glickman, Jonathan N., Williamson, Jessica A., Everett, Allen D., Redston, Mark, Fox, Edward A., Nakatani, Yoshihiro, Shivdasani, Ramesh A.

Publikováno v: Development (09501991); Jan2005, Vol. 132 Issue 2, p415-427, 13p, 3 Color Photographs, 2 Diagrams, 1 Chart, 1 Graph