N-terminal cleavage of cyclophilin D boosts its ability to bind F-ATP synthase.

Autor: Coluccino G; Department of Medicine, University of Udine, 33100, Udine, Italy., Negro A; Department of Biomedical Sciences, University of Padova, 35131, Padova, Italy., Filippi A; Department of Medicine, University of Udine, 33100, Udine, Italy., Bean C; Department of Medicine, University of Udine, 33100, Udine, Italy., Muraca VP; Department of Medicine, University of Udine, 33100, Udine, Italy., Gissi C; Department of Medicine, University of Udine, 33100, Udine, Italy., Canetti D; Centre for Amyloidosis, Division of Medicine, University College London, London, NW32PF, UK., Mimmi MC; Centre for Inherited Cardiovascular Diseases, IRCCS San Matteo Hospital Foundation, 27100, Pavia, Italy., Zamprogno E; Department of Medicine, University of Udine, 33100, Udine, Italy., Ciscato F; Department of Biomedical Sciences, University of Padova, 35131, Padova, Italy.; Institute of Neuroscience, National Research Council (CNR), 35131, Padova, Italy., Acquasaliente L; Department of Pharmaceutical & Pharmacological Sciences, University of Padova, 35131, Padova, Italy., De Filippis V; Department of Pharmaceutical & Pharmacological Sciences, University of Padova, 35131, Padova, Italy., Comelli M; Department of Medicine, University of Udine, 33100, Udine, Italy., Carraro M; Department of Biomedical Sciences, University of Padova, 35131, Padova, Italy., Rasola A; Department of Biomedical Sciences, University of Padova, 35131, Padova, Italy., Gerle C; Life Science Research Infrastructure Group, RIKEN SPring-8 Center, Kouto, Hyogo, Japan., Bernardi P; Department of Biomedical Sciences, University of Padova, 35131, Padova, Italy., Corazza A; Department of Medicine, University of Udine, 33100, Udine, Italy. alessandra.corazza@uniud.it., Lippe G; Department of Medicine, University of Udine, 33100, Udine, Italy. giovanna.lippe@uniud.it.

Publikováno v: Communications biology [Commun Biol] 2024 Nov 11; Vol. 7 (1), pp. 1486. Date of Electronic Publication: 2024 Nov 11.

Cyclophilin D in Mitochondrial Dysfunction: A Key Player in Neurodegeneration?

Autor: Coluccino G; Department of Medicine (DAME), University of Udine, 33100 Udine, Italy., Muraca VP; Department of Medicine (DAME), University of Udine, 33100 Udine, Italy., Corazza A; Department of Medicine (DAME), University of Udine, 33100 Udine, Italy., Lippe G; Department of Medicine (DAME), University of Udine, 33100 Udine, Italy.

Publikováno v: Biomolecules [Biomolecules] 2023 Aug 18; Vol. 13 (8). Date of Electronic Publication: 2023 Aug 18.

The Haves and Have-Nots: The Mitochondrial Permeability Transition Pore across Species.

Autor: Frigo E; Department of Biomedical Sciences and CNR Neuroscience Institute, University of Padova, Via Ugo Bassi 58/B, I-35131 Padova, Italy., Tommasin L; Department of Biomedical Sciences and CNR Neuroscience Institute, University of Padova, Via Ugo Bassi 58/B, I-35131 Padova, Italy., Lippe G; Department of Medicine, University of Udine, Piazzale Kolbe 4, I-33100 Udine, Italy., Carraro M; Department of Biomedical Sciences and CNR Neuroscience Institute, University of Padova, Via Ugo Bassi 58/B, I-35131 Padova, Italy., Bernardi P; Department of Biomedical Sciences and CNR Neuroscience Institute, University of Padova, Via Ugo Bassi 58/B, I-35131 Padova, Italy.

Publikováno v: Cells [Cells] 2023 May 17; Vol. 12 (10). Date of Electronic Publication: 2023 May 17.

The mitochondrial chaperone TRAP1 regulates F-ATP synthase channel formation.

Autor: Cannino G; Department of Biomedical Sciences, University of Padova, via U. Bassi 58/B, 35131, Padova, Italy., Urbani A; Department of Biomedical Sciences, University of Padova, via U. Bassi 58/B, 35131, Padova, Italy., Gaspari M; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, viale Europa, 88100, Catanzaro, Italy., Varano M; Research Centre for Advanced Biochemistry and Molecular Biology, Department of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, viale Europa, 88100, Catanzaro, Italy., Negro A; Department of Biomedical Sciences, University of Padova, via U. Bassi 58/B, 35131, Padova, Italy., Filippi A; Department of Medicine, University of Udine, via Colugna 50, 33100, Udine, Italy., Ciscato F; Department of Biomedical Sciences, University of Padova, via U. Bassi 58/B, 35131, Padova, Italy., Masgras I; Department of Biomedical Sciences, University of Padova, via U. Bassi 58/B, 35131, Padova, Italy.; Institute of Neuroscience, National Research Council, Viale G. Colombo 3, 35131, Padova, Italy., Gerle C; Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka, Japan.; RIKEN SPring-8 Center, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo, 679-5148, Japan., Tibaldi E; Department of Molecular Medicine, University of Padova, via Gabelli 63, 35121, Padova, Italy., Brunati AM; Department of Molecular Medicine, University of Padova, via Gabelli 63, 35121, Padova, Italy., Colombo G; Department of Chemistry, University of Pavia, via Taramelli 12, 27100, Pavia, Italy.; Institute of Chemical and Technological Sciences 'Giulio Natta'- SCITEC, Via Mario Bianco 9, 20131, Milano, Italy., Lippe G; Department of Medicine, University of Udine, via Colugna 50, 33100, Udine, Italy., Bernardi P; Department of Biomedical Sciences, University of Padova, via U. Bassi 58/B, 35131, Padova, Italy.; Institute of Neuroscience, National Research Council, Viale G. Colombo 3, 35131, Padova, Italy., Rasola A; Department of Biomedical Sciences, University of Padova, via U. Bassi 58/B, 35131, Padova, Italy. andrea.rasola@unipd.it.

Publikováno v: Cell death and differentiation [Cell Death Differ] 2022 Dec; Vol. 29 (12), pp. 2335-2346. Date of Electronic Publication: 2022 May 25.

Cerebrovascular atherosclerosis in type III hyperlipidemia is modulated by variation in the Apolipoprotein A5 gene

Autor: Evans D, Bode A, von der Lippe G, Beil FU, Mann WA

Publikováno v: European Journal of Medical Research, Vol 16, Iss 2, p 79 (2011)

Abstract Objective Type III Hyperlipoproteinemia is a rare lipid disorder with a frequency of 1-5 in 5000. It is characterized by the accumulation of triglyceride rich lipoproteins and patients are at increased risk of developping atherosclerosis. Ty

Externí odkaz: https://doaj.org/article/dd7c7150b50f4e029ac3b396d5d7dd9b