Výsledky vyhledávání - "Lipoproteins, HDL/metabolism"

Autor: Giuseppina Milano, Michele Samaja

Publikováno v: International Journal of Molecular Sciences
International journal of molecular sciences, vol. 21, no. 4, pp. 1527
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1527 (2020)

“The Chimera was, according to Greek mythology, a monstrous fire-breathing hybrid creature of Lycia in Asia Minor, composed of the parts of more than one animal [...]

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https://pubmed.ncbi.nlm.nih.gov/32102292

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HDLs Protect Pancreatic β-Cells Against ER Stress by Restoring Protein Folding and Trafficking

Autor: Christian Widmann, Florent Allagnat, Jean-Christophe Jonas, Gérard Waeber, Miguel Frias, Jean-Yves Chatton, Jannick Pétremand, Jessica Duprez, Richard W. James, Julien Puyal

Publikováno v: Diabetes, vol. 61, no. 5, pp. 1100-1111
Diabetes
DIABETES
Diabetes, Vol. 61, No 5 (2012) pp. 1100-11

Endoplasmic reticulum (ER) homeostasis alteration contributes to pancreatic β-cell dysfunction and death and favors the development of diabetes. In this study, we demonstrate that HDLs protect β-cells against ER stress induced by thapsigargin, cycl

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https://doi.org/10.2337/db11-1221

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The Scavenger Receptor Class B, Type I Is a Primary Determinant of Paraoxonase-1 Association With High-Density Lipoproteins

Autor: Ursula Seidler, Marie-Claude Brulhart-Meynet, Anurag K. Singh, Theo J.C. Van Berkel, Richard W. James, Sara Deakin, Brigitte Riederer, Ruud Out

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 30, No 11 (2010) pp. 2121-2127

Objective— To examine the contribution of the scavenger receptor (SR) BI to the mechanism by which high-density lipoprotein (HDL) acquires paraoxonase-1 (PON1). Methods and Results— Serum PON1 activity contributes to the antioxidant capacity of H

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https://doi.org/10.1161/atvbaha.110.209122

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HDLs, diabetes, and metabolic syndrome

Autor: Peter Vollenweider, Christian Widmann, Arnold von Eckardstein

Publikováno v: Handbook of Experimental Pharmacology, vol. 224, pp. 405-421
High Density Lipoproteins ISBN: 9783319096643
Handbook of Experimental Pharmacology

The prevalence of type 2 diabetes mellitus and of the metabolic syndrome is rising worldwide and reaching epidemic proportions. These pathologies are associated with significant morbidity and mortality, in particular with an excess of cardiovascular

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https://serval.unil.ch/resource/serval:BIB_3C43CB7B42B5.P001/REF.pdf

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High density lipoproteins and ischemia reperfusion injury: the therapeutic potential of HDL to modulate cell survival pathways

Autor: James, Richard William, Frias, Miguel

Publikováno v: Advances in Experimental Medicine and Biology, Vol. 824 (2014) pp. 19-26

The clinical importance of high density lipoproteins has grown in recent years with demonstrations of their impact on diverse pathological mechanisms implicated not only in vascular disease, but also in other physiological systems. This is related to

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https://archive-ouverte.unige.ch/unige:74406

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HDL-associated paraoxonase-1 can redistribute to cell membranes and influence sensitivity to oxidative stress

Autor: Richard W. James, Marie-Luce Bochaton-Piallat, Sara Deakin, Silvana Bioletto

Publikováno v: Free Radical Biology and Medicine, Vol. 50, No 1 (2011) pp. 102-9
Free radical biology & medicine

Paraoxonase-1 (PON1) is a high-density lipoprotein (HDL)-associated serum enzyme thought to make a major contribution to the antioxidant capacity of the lipoprotein. In previous studies, we proposed that HDL promoted PON1 secretion by transfer of the

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https://pubmed.ncbi.nlm.nih.gov/20850524

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Apolipoprotein A-V N-terminal Domain Lipid Interaction Properties in Vitro Explain the Hypertriglyceridemic Phenotype Associated with Natural Truncation Mutants*

Autor: Vincent Raussens, Kasuen Wong-Mauldin, Robert O. Ryan, Trudy M. Forte

Publikováno v: The Journal of biological chemistry, 284 (48

The N-terminal 146 residues of apolipoprotein (apo) A-V adopt a helix bundle conformation in the absence of lipid. Because similarly sized truncation mutants in human subjects correlate with severe hypertriglyceridemia, the lipid binding properties o

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https://europepmc.org/articles/PMC2785180/

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Components of the metabolic syndrome and risk for first-ever acute ischemic nonembolic stroke in elderly subjects

Autor: Milionis, H. J., Rizos, E., Goudevenos, J., Seferiadis, K., Mikhailidis, D. P., Elisaf, M. S.

BACKGROUND AND PURPOSE: Metabolic syndrome (MetSyn) represents a constellation of lipid and nonlipid risk factors for cardiovascular disease and is a recognized target for increased behavioral therapy. OBJECTIVE: The association between acute ischemi

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http://olympias.lib.uoi.gr/jspui/handle/123456789/22868

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Angiotensin II Promotes Selective Uptake of High Density Lipoprotein Cholesterol Esters in Bovine Adrenal Glomerulosa and Human Adrenocortical Carcinoma Cells Through Induction of Scavenger Receptor Class B Type I

Autor: Salman Azhar, Nicolas Demaurex, Nadia Cherradi, Serge Arnaudeau, Alessandro M. Capponi, Martine Bideau, Richard W. James

Publikováno v: Endocrinology
Endocrinology, Endocrine Society, 2001, 142 (10), pp.4540-4549. ⟨10.1210/endo.142.10.8412⟩
Endocrinology, Vol. 142, No 10 (2001) pp. 4540-9

International audience; Angiotensin II is one of the main physiological regulators of aldosterone biosynthesis in the zona glomerulosa of the adrenal cortex. The hormone stimulates intracellular cholesterol mobilization to the mitochondrion for stero

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https://hal.univ-grenoble-alpes.fr/hal-02459075

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High-density lipoproteins downregulate CCL2 production in human fibroblast-like synoviocytes stimulated by urate crystals

Autor: Leonardo Punzi, Anna Scanu, Carlo Agostini, Danielle Burger, Federica Frezzato, Assunta Pozzuoli, Lyssia Gruaz, Paolo Sfriso, Francesca Oliviero

Publikováno v: Arthritis Research & Therapy
Arthritis Research and Therapy, Vol. 12, No 1 (2010) P. R23

INTRODUCTION: To investigate whether monosodium urate (MSU) crystals induce the production of CCL2 (monocyte chemoattractant protein-1; MCP-1) in human fibroblast-like synoviocytes (FLS) and whether this mechanism would be affected by high-density li

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https://doi.org/10.1186/ar2930

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