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Human iPSC-derived photoreceptor transplantation in the cone dominant 13-lined ground squirrel.

Autor: Yu CT; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA., Kandoi S; Department of Ophthalmology, University of California, San Francisco, San Francisco, CA, USA; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA, USA., Periasamy R; Department of Ophthalmology and Visual Sciences, Medical College of Wisconsin, Milwaukee, WI, USA., Reddy LVK; Department of Ophthalmology, University of California, San Francisco, San Francisco, CA, USA; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA, USA., Follett HM; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA., Summerfelt P; Department of Ophthalmology and Visual Sciences, Medical College of Wisconsin, Milwaukee, WI, USA., Martinez C; Department of Ophthalmology, University of California, San Francisco, San Francisco, CA, USA; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA, USA., Guillaume C; Department of Ophthalmology and Visual Sciences, Medical College of Wisconsin, Milwaukee, WI, USA; School of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA., Bowie O; School of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA., Connor TB; Department of Ophthalmology and Visual Sciences, Medical College of Wisconsin, Milwaukee, WI, USA., Lipinski DM; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA; Department of Ophthalmology and Visual Sciences, Medical College of Wisconsin, Milwaukee, WI, USA., Allen KP; Department of Microbiology and Immunology, Biomedical Resource Center, Medical College of Wisconsin, Milwaukee, WI, USA., Merriman DK; Department of Biology, University of Wisconsin-Oshkosh, Oshkosh, WI, USA., Carroll J; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA; Department of Ophthalmology and Visual Sciences, Medical College of Wisconsin, Milwaukee, WI, USA., Lamba DA; Department of Ophthalmology, University of California, San Francisco, San Francisco, CA, USA; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA, USA. Electronic address: deepak.lamba@ucsf.edu.

Publikováno v: Stem cell reports [Stem Cell Reports] 2024 Mar 12; Vol. 19 (3), pp. 331-342. Date of Electronic Publication: 2024 Feb 08.

Downregulation of lysosomal trafficking in ARPE19 cells leads to decreased transfection efficiency at high passage.

Autor: Hood EMS; Department of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, WI, USA., Lipinski RAJ; Department of Biochemistry, Medical College of Wisconsin, WI, USA., Lipinski DM; Department of Cell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, WI, USA.; Department of Ophthalmology & Visual Sciences, Medical College of Wisconsin, WI, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jul 26. Date of Electronic Publication: 2023 Jul 26.

rAAV-mediated over-expression of acid ceramidase prevents retinopathy in a mouse model of Farber lipogranulomatosis.

Autor: Zhang H; Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.; Department of Ophthalmology and Visual Sciences, Medical College of Wisconsin, Milwaukee, WI, USA., Nagree MS; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Department of Pediatrics: Section of Hematology/Oncology/BMT, Medical College of Wisconsin, Milwaukee, WI, USA., Liu H; Department of Mathematics, Shanghai Normal University, Shanghai, China., Pan X; Department of Mathematics, Shanghai Normal University, Shanghai, China., Medin JA; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Department of Pediatrics: Section of Hematology/Oncology/BMT, Medical College of Wisconsin, Milwaukee, WI, USA.; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI, USA., Lipinski DM; Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA. dlipinski@mcw.edu.; Department of Ophthalmology and Visual Sciences, Medical College of Wisconsin, Milwaukee, WI, USA. dlipinski@mcw.edu.

Publikováno v: Gene therapy [Gene Ther] 2023 Apr; Vol. 30 (3-4), pp. 297-308. Date of Electronic Publication: 2022 Jul 28.

Identification of Novel Retinal Pericyte-Targeting rAAV Vectors Through Directed Evolution.

Autor: Patel DD; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.; Department of Ophthalmology and Visual Science, Medical College of Wisconsin, Milwaukee, WI, USA., Marsic D; Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA.; Porton Advanced Solutions, Suzhou, Jiangsu, China., Periasamy R; Department of Ophthalmology and Visual Science, Medical College of Wisconsin, Milwaukee, WI, USA., Zolotukhin S; Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL, USA., Lipinski DM; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.; Department of Ophthalmology and Visual Science, Medical College of Wisconsin, Milwaukee, WI, USA.

Publikováno v: Translational vision science & technology [Transl Vis Sci Technol] 2022 Aug 01; Vol. 11 (8), pp. 28.