Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lipika Salaye"'
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28470 (2011)
Computational methods are increasingly gaining importance as an aid in identifying active sites. Mostly these methods tend to have structural information that supplement sequence conservation based analyses. Development of tools that compute electros
Externí odkaz:
https://doaj.org/article/e6d947dbf2bb4509b6608a3684599e61
Autor:
Donald A. McClain, Robert C. Cooksey, Ielizaveta Bychkova, Sandy Sink, Felipe Lorenzo, Kylie Kavanagh, Herbert L. Bonkovsky, Manish S. Bharadwaj, Soh-Hyun Lee, Shalini Jain, Nuwan T. Meegalla, Alexandria Harrison, Lipika Salaye, George L. Donati, Ashley T. Davis, Katherine Turnbull, Alexander J. Kovalic
Publikováno v:
Nutrients
Volume 11
Issue 9
Nutrients, Vol 11, Iss 9, p 2172 (2019)
Volume 11
Issue 9
Nutrients, Vol 11, Iss 9, p 2172 (2019)
High tissue iron levels are a risk factor for multiple chronic diseases including type 2 diabetes mellitus (T2DM) and non-alcoholic fatty liver disease (NAFLD). To investigate causal relationships and underlying mechanisms, we used an established NAF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a2636f1ce6907f8933d4d6fdb1e3b92
http://europepmc.org/articles/PMC6769937
http://europepmc.org/articles/PMC6769937
Publikováno v:
Diabetes. 67
Iron is a risk factor for type 2 diabetes, but its relationship to other aspects of metabolic syndrome is less clear. To investigate iron’s relation to nonalcoholic steatohepatitis (NASH), mice were fed a “fast food” (FF)-diet (40% energy as fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a093bf3bf37be82a33aa5ee4955e110
https://doi.org/10.2337/db18-1881-p
https://doi.org/10.2337/db18-1881-p
Autor:
Felipe R. Lorenzo, Neeraj Sharma, Carl D. Langefeld, Lipika Salaye, Shalini Jain, Swapan K Das, Donald A. McClain, Mary E. Comeau
Publikováno v:
Diabetes. 67
Iron is an important micronutrient involved in several metabolic processes, and excessive iron is a risk factor for insulin resistance (IR) and diabetes. To define the genetic regulation of iron metabolism and its role in IR, we used gene expression,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fbb44791a65441026485fa31b8a7f2c
https://doi.org/10.2337/db18-1760-p
https://doi.org/10.2337/db18-1760-p
Autor:
Mary E. Comeau, Shalini Jain, Swapan K Das, Neeraj K. Sharma, Donald A. McClain, Carl D. Langefeld, Felipe R. Lorenzo, Alexandria Harrison, Lipika Salaye
Publikováno v:
The Journal of clinical endocrinology and metabolism. 103(11)
CONTEXT: Excessive body iron stores are a risk factor for decreased insulin sensitivity (S(I)) and diabetes. We hypothesized that transcriptional dysregulation of genes involved in iron metabolism in adipocytes causes insulin resistance. OBJECTIVE AN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e922d68ee26d11a95937894ce9b616
https://pubmed.ncbi.nlm.nih.gov/30099506
https://pubmed.ncbi.nlm.nih.gov/30099506
Autor:
Sandeep, Chakraborty, Renu, Minda, Lipika, Salaye, Abhaya M, Dandekar, Swapan K, Bhattacharjee, Basuthkar J, Rao
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 978
Error-prone PCR, DNA shuffling, and saturation mutagenesis are techniques used by protein engineers to mimic the natural "evolutionary walk" that conjures new enzymes. Rational design is often critical in efforts to accelerate this "random walk" into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9a901c2dad87c9ce23d601b86bfdcb24
https://pubmed.ncbi.nlm.nih.gov/23423899
https://pubmed.ncbi.nlm.nih.gov/23423899
Autor:
Basuthkar J. Rao, Lipika Salaye, Sandeep Chakraborty, Abhaya M. Dandekar, Renu Minda, Swapan K. Bhattacharjee
Publikováno v:
Methods in Molecular Biology ISBN: 9781627032926
Error-prone PCR, DNA shuffling, and saturation mutagenesis are techniques used by protein engineers to mimic the natural "evolutionary walk" that conjures new enzymes. Rational design is often critical in efforts to accelerate this "random walk" into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfae37eb2be44a4910bf4207721cddf9
https://doi.org/10.1007/978-1-62703-293-3_15
https://doi.org/10.1007/978-1-62703-293-3_15
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 12, p e28470 (2011)
PLoS ONE, Vol 6, Iss 12, p e28470 (2011)
Computational methods are increasingly gaining importance as an aid in identifying active sites. Mostly these methods tend to have structural information that supplement sequence conservation based analyses. Development of tools that compute electros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a317768ef84f559ae52725cf173bce
https://pubmed.ncbi.nlm.nih.gov/22174814
https://pubmed.ncbi.nlm.nih.gov/22174814