Zobrazeno 1 - 10
of 19 057
pro vyhledávání: '"Lipid nanoparticles"'
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Messenger RNA (mRNA) vaccines are a key technology in combating existing and emerging infectious diseases. However, improving the immunogenicity and durability of mRNA vaccines remains a challenge. To elicit optimal immune responses, integra
Externí odkaz:
https://doaj.org/article/a0bb94a0b6834b228556ac4471b1f7e8
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background The efficacy of mRNA-based vaccines and therapies relies on lipid nanoparticles (LNPs) as carriers to deliver mRNA into cells. The chemical structure of ionizable lipids (ILs) within LNPs is crucial in determining their delivery e
Externí odkaz:
https://doaj.org/article/8ac1045f5fd446a4bea06ed1f5746ab6
Autor:
Mahsa Mottaghi, Parisa Karami, Zahra Hesari, Sara Nemati, Hanieh Mohammad Rahimi, Hamed Mirjalali
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background The fabrication of anti-Toxoplasma drugs with less side effects and desirable efficacy is one of the important research goals facing with toxoplasmosis. This study aimed to determine the anti-Toxoplasma effects of Cinnamon zeylani
Externí odkaz:
https://doaj.org/article/e143032bb11546038709179b595c84ec
Publikováno v:
Veterinary World, Vol 17, Iss 10, Pp 2235-2247 (2024)
Background and Aim: Ticks are blood-feeding ectoparasites that transmit pathogens to animals and humans. One of the most important hard ticks in animals is Rhipicephalus microplus, which transmits Babesia and Anaplasma spp. Although many potential ti
Externí odkaz:
https://doaj.org/article/6cb0c2546100453589aacdefd3d72fb1
Autor:
Karroum Reem, Üçışık Mehmet Hikmet
Publikováno v:
Türk Biyokimya Dergisi, Vol 49, Iss 5, Pp 629-636 (2024)
Sulforaphane is well-known for its anti-cancer properties particularly against breast, skin and prostate cancers. High sensitivity of sulforaphane to oxygen, heat, and alkaline conditions, as well as its poor oral bioavailability and water instabilit
Externí odkaz:
https://doaj.org/article/c38c072a40b04ae8a862aad8a85194d3
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The messenger ribose nucleic acid (mRNA) in the form of Corona virus of 2019 (COVID-19) vaccines were effectively delivered through lipid nanoparticles (LNP) proving its use as effective carriers in clinical applications. In the present work
Externí odkaz:
https://doaj.org/article/d9cef7be40814275913de7d5973735a4
Publikováno v:
陆军军医大学学报, Vol 46, Iss 17, Pp 1925-1933 (2024)
Objective To construct lipid nanoparticles (lipopeptide-lipid nanoparticle, LP-LNP) with novel lipopeptides as adjuvants, and initially explore their synergistic effect on mRNA vaccines. Methods Two novel lipopeptides, SS-10 and SQ18, were designed a
Externí odkaz:
https://doaj.org/article/cbed35ed90de41e9b11e44b69796077c
Autor:
Ruei-Min Lu, Hsiang-En Hsu, Ser John Lynon P. Perez, Monika Kumari, Guan-Hong Chen, Ming-Hsiang Hong, Yin-Shiou Lin, Ching-Hang Liu, Shih-Han Ko, Christian Angelo P. Concio, Yi-Jen Su, Yi-Han Chang, Wen-Shan Li, Han-Chung Wu
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-36 (2024)
Abstract Realizing the immense clinical potential of mRNA-based drugs will require continued development of methods to safely deliver the bioactive agents with high efficiency and without triggering side effects. In this regard, lipid nanoparticles h
Externí odkaz:
https://doaj.org/article/0f6655b8145d4bda96e5f7a52141ca40
Autor:
Weiwen Kong, Yuning Wei, Zirong Dong, Wenjuan Liu, Jiaxin Zhao, Yan Huang, Jinlong Yang, Wei Wu, Haisheng He, Jianping Qi
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Lipid nanoparticles (LNPs) are currently the most commonly used non-viral gene delivery system. Their physiochemical attributes, encompassing size, charge and surface modifications, significantly affect their behaviors both in vivo and in vi
Externí odkaz:
https://doaj.org/article/9c35edf2f07c4315bcb41f882acf08ee
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 10, Iss 1, Pp 1-38 (2024)
Abstract Background Skin cancer continues to be an imperative global health issue, urging continuous exploration of treatment methodologies. Conventional treatments for skin cancer include surgical interventions, immunotherapy, targeted therapy, chem
Externí odkaz:
https://doaj.org/article/e1bde0ca3b4642efb217b2cb0c91352a