Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Lipeng, Mao"'
Autor:
Songnan Sui, Mengjun Zhong, Shuxin Zhong, Xueting Peng, Lipeng Mao, Cunte Chen, Chengwu Zeng, Oscar Junhong Luo, Yangqiu Li
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Background Exhaustion is a key factor that influences the efficacy of chimeric antigen receptor T (CAR-T) cells. Our previous study demonstrated that a bromodomain protein 4 (BRD4) inhibitor can revise the phenotype and function of exhausted
Externí odkaz:
https://doaj.org/article/4ffb6b26b2d74680b653b6d87757a4c9
Autor:
Yun Tian, Jiafan Guo, Lipeng Mao, Zhixi Chen, Xingwei Zhang, Yangqiu Li, Yikai Zhang, Xianfeng Zha, Oscar Junhong Luo
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Background Quiescent self-renewal of leukemia stem cells (LSCs) and resistance to conventional chemotherapy are the main factors leading to relapse of acute myeloid leukemia (AML). Alpha-enolase (ENO1), a key glycolytic enzyme, has been show
Externí odkaz:
https://doaj.org/article/1b76bb0bad774a7c84ce0c6890428e9f
A novel method for identifying SARS-CoV-2 infection mutants via an epitope-specific CD8+ T cell test
Autor:
Congling Qiu, Bo Peng, Chanchan Xiao, Pengfei Chen, Lipeng Mao, Xiaolu Shi, Zhen Zhang, Ziquan Lv, Qiuying Lv, Xiaomin Zhang, Jiaxin Li, Yanhao Huang, Qinghua Hu, Guobing Chen, Xuan Zou, Xiaofeng Liang
Publikováno v:
Biosafety and Health, Vol 6, Iss 3, Pp 143-152 (2024)
Since the outbreak of the coronavirus disease 2019 (COVID-19) epidemic in 2019, the public health system has faced enormous challenges. Tracking the individuals who test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a k
Externí odkaz:
https://doaj.org/article/ae578ee31b90473890eb6156715b17ff
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Apatinib was the first anti-angiogenic agent approved for treatment of metastatic gastric cancer (GC). However, the emergence of resistance was inevitable. Thus investigating new and valuable off-target effect of apatinib directly against ca
Externí odkaz:
https://doaj.org/article/569eb4a3138c4e2886b059fcf7ef856f
Autor:
Ling Sun, Wenwu Zhu, Yuan Ji, Ailin Zou, Lipeng Mao, Boyu Chi, Jianguang Jiang, Xuejun Zhou, Qingjie Wang, Fengxiang Zhang
Publikováno v:
Endocrine Connections, Vol 11, Iss 7, Pp 1-9 (2022)
Objective: Post-treatment contrast-induced acute kidney injury (CI-AKI) is associated with poor outcomes in patients with acute myocardial infarction (AMI). A lower free triiodothyronine (FT3) level predicts a poor prognosis of AMI patients. This stu
Externí odkaz:
https://doaj.org/article/6b3aff3d88d842d8ae9955384d423e40
Autor:
Wenpu Lai, Xiaofang Wang, Lian Liu, Ling Xu, Lipeng Mao, Jiaxiong Tan, Xianfeng Zha, Huien Zhan, Wen Lei, Yu Lan, Guobing Chen, Yangqiu Li, Oscar Junhong Luo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionThe character and composition of leukemia-related T cells are closely related to the treatment response and prognosis for patients. Though B cell-acute lymphoblastic leukemia (B-ALL) patients have benefited from immune-based approaches, s
Externí odkaz:
https://doaj.org/article/66dd6f4ec8bf49a98bff5a83de614b62
Autor:
Dabei Cai, Tingting Xiao, Ailin Zou, Lipeng Mao, Boyu Chi, Yu Wang, Qingjie Wang, Yuan Ji, Ling Sun
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundPredictive models based on machine learning have been widely used in clinical practice. Patients with acute myocardial infarction (AMI) are prone to the risk of acute kidney injury (AKI), which results in a poor prognosis for the patient. T
Externí odkaz:
https://doaj.org/article/ecea451b0e1f44a59ff3bc7aed373f29
Autor:
Chanchan Xiao, Lipeng Mao, Zhigang Wang, Lijuan Gao, Guodong Zhu, Jun Su, Xiongfei Chen, Jun Yuan, Yutian Hu, Zhinan Yin, Jun Xie, Weiqing Ji, Haitao Niu, Feng Gao, Oscar Junhong Luo, Lianbo Xiao, Pengcheng Wang, Guobing Chen
Publikováno v:
iScience, Vol 25, Iss 3, Pp 103934- (2022)
Summary: Here, we evaluated the immune properties of the HLA-A2 restricted CD8+ T cell epitopes containing mutations from B.1.1.7, and furthermore performed a comprehensive analysis of the SARS-CoV-2 specific CD8+ T cell responses from COVID-19 conva
Externí odkaz:
https://doaj.org/article/84fa3bb0dcf646eba78495fa0f634db6
Autor:
Yang Hu, Yudai Xu, Lipeng Mao, Wen Lei, Jian Xiang, Lijuan Gao, Junxing Jiang, Li`an Huang, Oscar Junhong Luo, Jinhai Duan, Guobing Chen
Publikováno v:
Frontiers in Aging, Vol 2 (2022)
Human immune system functions over an entire lifetime, yet how and why the immune system becomes less effective with age are not well understood. Here, we characterize peripheral blood mononuclear cell transcriptome from 132 healthy adults with 21–
Externí odkaz:
https://doaj.org/article/cac52df82cca48aa8fca84882a38c918
Autor:
Congling Qiu, Chanchan Xiao, Zhigang Wang, Guodong Zhu, Lipeng Mao, Xiongfei Chen, Lijuan Gao, Jieping Deng, Jun Su, Huanxing Su, Evandro Fei Fang, Zhang-Jin Zhang, Jikai Zhang, Caojun Xie, Jun Yuan, Oscar Junhong Luo, Li`an Huang, Pengcheng Wang, Guobing Chen
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
We identified SARS-CoV-2 specific antigen epitopes by HLA-A2 binding affinity analysis and characterized their ability to activate T cells. As the pandemic continues, variations in SARS-CoV-2 virus strains have been found in many countries. In this s
Externí odkaz:
https://doaj.org/article/ea5a4dcfda90462788d704486092646e