Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lioudmila Campbell"'
Autor:
Do Jin Kim, Greta Van Slyke, Miles B. Brennan, Nicholas J. Mantis, Peter J. Didier, Neil Mlakar, Zachary A. Bornholdt, Ellen S. Vitetta, Dylan J. Ehrbar, Lioudmila Campbell, Kevin J. Whaley, Fernando J Torres-Velez, Chad J. Roy, Michelle Chen, Larry Zeitlin, Jeffrey W Froude, Lara A. Doyle-Meyers
Publikováno v:
npj Vaccines, Vol 5, Iss 1, Pp 1-8 (2020)
NPJ Vaccines
NPJ Vaccines
Inhalation of ricin toxin (RT), a Category B biothreat agent, provokes an acute respiratory distress syndrome marked by pro-inflammatory cytokine and chemokine production, neutrophilic exudate, and pulmonary edema. The severity of RT exposure is attr
Autor:
William S. Shestowsky, Thomas W. Geisbert, Dafna M. Abelson, Abhishek N. Prasad, Krystle N. Agans, Elaine Bunyan, Lioudmila Campbell, Daniel J. Deer, Karla A. Fenton, Viktoriya Borisevich, Do Han Kim, Robert W. Cross, Joan B. Geisbert, Larry Zeitlin, Zachary A. Bornholdt, Danielle P. Porter
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications
Nature Communications
Monoclonal antibodies (mAbs) and remdesivir, a small-molecule antiviral, are promising monotherapies for many viruses, including members of the genera Marburgvirus and Ebolavirus (family Filoviridae), and more recently, SARS-CoV-2. One of the major c
Autor:
Mark Horn, Ruth Muchekehu, Joselyn Del Rosario, Steven Pirie-Shepherd, Allan Kaspar, Dingguo Liu, Venkata Doppalapudi, Trina Osothprarop, Julia Coronella, Haim Moskowitz, Michael Bacica, Lioudmila Campbell, Anouk Dirksen
Publikováno v:
Translational oncology. 6(5)
Poor drug delivery and penetration of antibody-mediated therapies pose significant obstacles to effective treatment of solid tumors. This study explored the role of pharmacokinetics, valency, and molecular weight in maximizing drug delivery. Biodistr
Autor:
Kristen E Bower, Ryan Preston, Emily Corner, Robert E. Murphy, Arvind G. Kinhikar, Xia Cao, Zemeda W Ainekulu, Aakash B Datt, Steven Pirie-Shepherd, Lioudmila Campbell, Gang Chen, Venkata Doppalapudi, Joselyn Del Rosario, Hanhua Huang, Bryan Oates, Rodney W. Lappe, Son Lam, Trina Osothprarop, Nancy Levin, Curt Bradshaw, Gary Woodnutt, Julie A Hoye, Judith Jimenez
Publikováno v:
Journal of medicinal chemistry. 54(5)
Novel phage-derived peptides are the first reported molecules specifically targeting human placental growth factor 1 (PlGF-1). Phage data enabled peptide modifications that decreased IC(50) values in PlGF-1/VEGFR-1 competition ELISA from 100 to 1 μM
Autor:
Jingping Zhong, Johnson Kimberly Sue, Gang Chen, Yanwen Fu, Abhijit Bhat, Julia Coronella, Joselyn Del Rosario, Dorian Willhite, Nancy Levin, Gary Woodnutt, Lioudmila Campbell
Publikováno v:
Cancer Research. 73:4113-4113
The SDF1α / CXCR4 axis contributes to cancer metastasis, proliferation, angiogenesis and resistance to standard of care drugs. Here we describe novel phage display derived peptide SDF1α antagonists. Phage displayed peptides were optimized through a