Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Liora Schultz"'
Autor:
Claire Johns, Courtney Erickson, Ashley Jacobs, Jennifer Moon, Christina Baggott, Regina Dagher, Helen Nadel, Jay Balagtas, Catherine Aftandilian, Sneha Ramakrishna, Norman Lacayo, Kara L. Davis, Elliot Stieglitz, Liora Schultz
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Standard testing for disease evaluation in B-cell acute lymphoblastic leukemia (B-ALL) includes examination of the bone marrow and cerebrospinal fluid. Radiographic or functional imaging are indicated when clinical signs of non-CNS extramedullary dis
Externí odkaz:
https://doaj.org/article/804f63d9ff31435e95f8f42657723ec2
Autor:
Crystal L Mackall, Christina Baggott, Kara Lynn Davis, Liora Schultz, Ann Walkush, Courtney Erickson, Sneha Ramakrishna, Catherine Aftandilian, Norman Lacayo, Helen Ruth Nadel, Jean Oak
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 2 (2023)
Background: Chimeric antigen receptor (CAR) T cell therapy is an effective salvage therapy for pediatric relapsed B-cell acute lymphoblastic leukemia (B-ALL), yet is challenged by high rates of post-CAR relapse. Literature describing specific relapse
Externí odkaz:
https://doaj.org/article/0898e66bc0de4d3099ca0993cfc0cfe9
Autor:
Agnes Reschke, Rebecca M. Richards, Stephanie M. Smith, Adrienne H. Long, Lianna J. Marks, Liora Schultz, Jennifer L. Kamens, Catherine Aftandilian, Kara L. Davis, Tanja Gruber, Kathleen M. Sakamoto
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Clinical pathways are evidence-based tools that have been integrated into many aspects of pediatric hospital medicine and have proven effective at reducing in-hospital complications from a variety of diseases. Adaptation of similar tools for specific
Externí odkaz:
https://doaj.org/article/8332e18e0fec4a0eaad8f1efab2764b2
Autor:
Liora Schultz
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Chimeric Antigen Receptor (CAR) T cell therapy targeting CD19 has introduced a paradigmatic shift in our treatment approach for advanced B cell malignancies. A major advance has been in the field of pediatric B-ALL where complete responses have been
Externí odkaz:
https://doaj.org/article/e36d76dcc5cd4da0bf661b36921cfc8a
Autor:
Rupa Narayan, Niclas Olsson, Lisa E Wagar, Bruno C Medeiros, Everett Meyer, Debra Czerwinski, Michael S Khodadoust, Lichao Zhang, Liora Schultz, Mark M Davis, Joshua E Elias, Ron Levy
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219547 (2019)
Somatic mutations in cancer are a potential source of cancer specific neoantigens. Acute myeloid leukemia (AML) has common recurrent mutations shared between patients in addition to private mutations specific to individuals. We hypothesized that neoa
Externí odkaz:
https://doaj.org/article/edb0390b578b4750b2577bb7b8e15027
Autor:
Jasia Mahdi, Jorg Dietrich, Karin Straathof, Claire Roddie, Brian J. Scott, Tom Belle Davidson, Laura M. Prolo, Tracy T. Batchelor, Cynthia J. Campen, Kara L. Davis, Juliane Gust, Michael Lim, Robbie G. Majzner, Julie R. Park, Sonia Partap, Sneha Ramakrishna, Rebecca Richards, Liora Schultz, Nicholas A. Vitanza, Leo D. Wang, Crystal L. Mackall, Michelle Monje
Publikováno v:
Nature Medicine. 29:803-810
Autor:
Sean Green, Liora Schultz
Publikováno v:
Current Oncology Reports.
Autor:
Sneha Ramakrishna, Zinaida Good, Moksha Desai, Daniel Zamler, Rebecca Mancusi, Jasia Mahdi, Robbie Majzner, Liora Schultz, Rebecca Richards, Jennifer Kamens, Valentin Barsan, Cynthia Campen, Sonia Partap, Zachary Ehlinger, Warren Reynolds, Yiyun Chen, Mark P. Hamilton, Jennifer Moon, Christina Baggott, Michael Kunicki, Michelle Fujimoto, Amy Li, Sneha Jariwala, Sharon Mavroukakis, Emily Egeler, Ashley Jacobs, Courtney Erickson, Karen Yamabe-Kwong, Snehit Prabhu, Kara Davis, Steve Feldman, Bita Sahaf, Crystal L. Mackall, Michelle Monje
Publikováno v:
Cancer Research. 83:959-959
Introduction: H3K27M-mutated diffuse intrinsic pontine glioma (DIPG) and spinal cord diffuse midline glioma (DMG) are universally lethal central nervous system (CNS) tumors in children and young adults. We previously demonstrated safety and activity
Autor:
Liora Schultz, Kara Lynn Davis, Ann Walkush, Christina Baggott, Courtney Erickson, Sneha Ramakrishna, Catherine Aftandilian, Norman Lacayo, Helen Ruth Nadel, Jean Oak, Crystal L Mackall
Publikováno v:
Journal for ImmunoTherapy of Cancer. 11:e004851
Chimeric antigen receptor (CAR) T cell therapy is an effective salvage therapy for pediatric relapsed B-cell acute lymphoblastic leukemia (B-ALL), yet is challenged by high rates of post-CAR relapse. Literature describing specific relapse patterns an
Autor:
Michelle Monje, Robbie Majzner, Jasia Mahdi, Sneha Ramakrishna, Shabnum Patel, Harshini Chinnasamy, Kristen Yeom, Liora Schultz, Valentin Barsan, Rebecca Richards, Cynthia Campen, Agnes Reschke, Angus Martin Toland, Christina Baggott, Sharon Mavroukakis, Emily Egeler, Jennifer Moon, Ashley Jacobs, Karen Yamabe-Kwong, Lindsey Rasmussen, Esther Nie, Sean Green, Michael Kunicki, Michele Fujimoto, Zach Ehlinger, Warren Reynolds, Snehit Prabhu, Katherine E Warren, Tim Cornell, Sonia Partap, Paul Fisher, Gerald Grant, Hannes Vogel, Bita Sahaf, Kara Davis, Steven Feldman, Crystal Mackall
Publikováno v:
Neuro-Oncology. 24:i20-i21
BACKGROUND: H3K27M-mutated DMGs express high levels of the disialoganglioside GD2 and GD2-CAR T-cells (GD2-CART) regress DMG in preclinical models. METHODS: NCT04196413 is a 3 + 3 Phase I dose escalation trial testing GD2-CART in patients with biopsy