Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Liora S Katz"'
Autor:
Nataly Shtraizent, Charles DeRossi, Shikha Nayar, Ravi Sachidanandam, Liora S Katz, Adam Prince, Anna P Koh, Adam Vincek, Yoav Hadas, Yujin Hoshida, Donald K Scott, Efrat Eliyahu, Hudson H Freeze, Kirsten C Sadler, Jaime Chu
Publikováno v:
eLife, Vol 6 (2017)
Rapid cellular proliferation in early development and cancer depends on glucose metabolism to fuel macromolecule biosynthesis. Metabolic enzymes are presumed regulators of this glycolysis-driven metabolic program, known as the Warburg effect; however
Externí odkaz:
https://doaj.org/article/2d882b0e6ea14d7787b09ec9d5be2a23
Autor:
Liora Segal, Liora S Katz, Hagit Shapira, Judith Sandbank, Elizabeth Geras-Raaka, Marvin C Gershengorn, Yoram Oron
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93879 (2014)
The balance between the adhesion of cancer cells to extracellular matrix and their migratory potential, as well as their proteolytic activity, are important parameters that determine cancer cells invasiveness and metastasis. Since thrombin has been i
Externí odkaz:
https://doaj.org/article/a2ffadeefc454d9d9e7e3af54be2f62b
Autor:
Liora S. Katz, Gabriel Brill, Peng Wang, Luca Lambertini, Pili Zhang, Jonathan M. Haldeman, Hongtao Liu, Christopher B. Newgard, Andrew F. Stewart, Adolfo Garcia-Ocaña, Donald K. Scott
Publikováno v:
Molecular Metabolism, Vol 79, Iss , Pp 101848- (2024)
Objective: All forms of diabetes result from insufficient functional β-cell mass. Thus, achieving the therapeutic goal of expanding β-cell mass requires a better mechanistic understanding of how β-cells proliferate. Glucose is a natural β-cell mi
Externí odkaz:
https://doaj.org/article/ca3bb72876334491840e4095754b390d
Autor:
Liora S. Katz, Gabriel Brill, Pili Zhang, Anil Kumar, Sharon Baumel-Alterzon, Lee B. Honig, Nicolás Gómez-Banoy, Esra Karakose, Marius Tanase, Ludivine Doridot, Alexandra Alvarsson, Bennett Davenport, Peng Wang, Luca Lambertini, Sarah A. Stanley, Dirk Homann, Andrew F. Stewart, James C. Lo, Mark A. Herman, Adolfo Garcia-Ocaña, Donald K. Scott
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
ChREBP is a glucose-responsive transcription factor, which regulates glucose-mediated proliferation and cell death in pancreatic β-cells. Here the authors show that the acute feed forward induction of ChREBPβ is required for adaptive β-cell expans
Externí odkaz:
https://doaj.org/article/f2c908c5343543e98a1a127b3ec55963
Publikováno v:
Molecular Metabolism, Vol 66, Iss , Pp 101646- (2022)
Objectives: Thyroid hormone (T3) and high glucose concentrations are critical components of β-cell maturation and function. In the present study, we asked whether T3 and glucose signaling pathways coordinately regulate transcription of genes importa
Externí odkaz:
https://doaj.org/article/b76e13ec8db8451ba0d2e3059a19aa52
Autor:
Karin J. Bosma, Spencer R. Andrei, Liora S. Katz, Ashley A. Smith, Jennifer C. Dunn, Valerie F. Ricciardi, Marisol A. Ramirez, Sharon Baumel-Alterzon, William A. Pace, Darian T. Carroll, Emily M. Overway, Elysa M. Wolf, Michelle E. Kimple, Quanhu Sheng, Donald K. Scott, Richard M. Breyer, Maureen Gannon
Publikováno v:
Molecular Metabolism, Vol 54, Iss , Pp 101347- (2021)
Objective: Type 2 diabetes is characterized by hyperglycemia and inflammation. Prostaglandin E2, which signals through four G protein-coupled receptors (EP1-4), is a mediator of inflammation and is upregulated in diabetes. We have shown previously th
Externí odkaz:
https://doaj.org/article/938250ff8f6d4937886d25473129e45f
Autor:
Shenhav, Yaniv S. Ovadia, Dov Gefel, Yoel Toledano, Shani R. Rosen, Yael Avrahami-Benyounes, Ludmila Groisman, Efrat Rorman, Lihi Hen, Shlomo Fytlovich, Liora S. Katz, Eyal Y. Anteby, Simon
Publikováno v:
Nutrients; Volume 15; Issue 13; Pages: 2914
It is unclear how maternal glycemic status and maternal iodine status influence birth weight among individuals with mild-to-moderate iodine deficiency (ID). We studied the association between birth weight and both maternal glucose levels and iodine i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::50c3eaaab77c468befcc6ec4a9d3af15
Autor:
Yaniv S. Ovadia, Dov Gefel, Yoel Toledano, Shani Rosen, Yael Avrahami-Benyounes, Ludmila Groisman, Efrat Rorman, Lihi Hen, Shlomo Fytlovich, Liora S Katz, Eyal Y Anteby, Simon Shenhav
It is unclear how maternal glycemic status and maternal iodine status influence birth weight in mild-to-moderate iodine deficiency (ID). We studied the association between birth weight and both maternal glucose levels and iodine intake in pregnant wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37e6a270ad3510ae25758437d65c6343
https://doi.org/10.20944/preprints202305.2034.v1
https://doi.org/10.20944/preprints202305.2034.v1
Autor:
Liora S. Katz, Gabriel Brill, Pili Zhang, Anil Kumar, Sharon Baumel-Alterzon, Lee B. Honig, Nicolás Gómez-Banoy, Esra Karakose, Marius Tanase, Ludivine Doridot, Alexandra Alvarsson, Bennett Davenport, Peng Wang, Luca Lambertini, Sarah A. Stanley, Dirk Homann, Andrew F. Stewart, James C. Lo, Mark A. Herman, Adolfo Garcia-Ocaña, Donald K. Scott
Publikováno v:
Nature Communications. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71f34f530ffaa7e2547e03767dab3698
https://doi.org/10.1038/s41467-022-33243-7
https://doi.org/10.1038/s41467-022-33243-7
Publikováno v:
Diabetes. 71
Glucotoxicity is a major mediator of β-cell dysfunction derived from prolonged hyperglycemia. A better understanding of glucotoxicity and preservation of β-cell mass are urgently needed. Carbohydrate response element binding protein (ChREBP) is a g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8d929f42135480eba9c1f0c7662d290
https://doi.org/10.2337/db22-12-or
https://doi.org/10.2337/db22-12-or