Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lior Roitman"'
Autor:
Adi Sagiv, Amir Bar-Shai, Naama Levi, Miki Hatzav, Lior Zada, Yossi Ovadya, Lior Roitman, Gal Manella, Ofer Regev, Julia Majewska, Ezra Vadai, Raya Eilam, Sara W. Feigelson, Michael Tsoory, Michel Tauc, Ronen Alon, Valery Krizhanovsky
Publikováno v:
Cell Reports, Vol 22, Iss 13, Pp 3468-3479 (2018)
Summary: The tumor suppressor p53 limits tumorigenesis by inducing apoptosis, cell cycle arrest, and senescence. Although p53 is known to limit inflammation during tumor development, its role in regulating chronic lung inflammation is less well under
Externí odkaz:
https://doaj.org/article/3f1c19548e7f4fcf87e7ad6139d3663b
Autor:
Julia Majewska, Amit Agrawal, Avi Mayo, Lior Roitman, Rishita Chatterjee, Jarmila Kralova, Tomer Landsberger, Yonatan Katzenelenbogen, Tomer Meir-Salame, Efrat Hagai, Nemanja Stanojevic, Ido Amit, Uri Alon, Valery Krizhanovsky
The accumulation of senescent cells promotes aging, but a molecular mechanism that senescent cells use to evade immune clearance and accumulate remains to be elucidated. Here, we report that p16-positive senescent cells upregulate the immune checkpoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc4e2f7227e83507ed7a204748568db2
https://doi.org/10.1101/2023.01.30.524522
https://doi.org/10.1101/2023.01.30.524522
Autor:
Adi Nagler, Kuoyuan Cheng, Alexandre Reuben, Kun Wang, Deborah Nejman, Mitchell P. Levesque, Maya Lotan-Pompan, Ron Rotkopf, Chantale Bernatchez, Adina Weinberger, Jessica Galloway-Peña, Ronen Levy, Sarah B. Johnson, Scott N. Peterson, Jennifer A. Wargo, Jacob Schachter, Yardena Samuels, Aviyah Peri, Polina Greenberg, Tali Dadosh, Leandro C. Hermida, Ofra Golani, Eilon Barnea, Noam Shental, Naama Geva-Zatorsky, Yishai Levin, Lior Roitman, Garold Fuks, David J. Adams, Eran Segal, Leore T. Geller, William C Shropshire, Cara Haymaker, Raya Eilam, Ravid Straussman, Michal Lotem, Kevin Vervier, Chaya Barbolin, Neerupma Bhardwaj, Smadar Levin-Zaidman, Arie Admon, Yuval Bussi, Gal Yagel, Michal Alon, Eytan Ruppin, Gil Benedek, Steven L. C. Ketelaars, Shelly Kalaora, Trevor D. Lawley, Sophie Trabish, Reetakshi Arora, Pia Kvistborg, Michal J. Besser
Publikováno v:
Nature
A variety of species of bacteria are known to colonize human tumours1–11, proliferate within them and modulate immune function, which ultimately affects the survival of patients with cancer and their responses to treatment12–14. However, it is no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4e3a8e26499995bc3104dc84f785da
https://europepmc.org/articles/PMC9717498/
https://europepmc.org/articles/PMC9717498/
Autor:
Areej Khatib, Lior Roitman, Sharona Elgavish, Narmen Azazmeh, Anna Hochner-Ger, Eli Pikarsky, Gideon Zamir, Rachel Kalifa, Benjamin Assouline, Jonathan Demma, Yonatan Khalatnik, Yehuda Schlesinger, Yuval Dor, Karen Meir, Hadar Benyamini, Valery Krizhanovsky, Oren Parnas, Ittai Ben-Porath, Shaul Horwitz, Ashraf Imam, Karine Atlan, Yossi Ovadya, Dror Kolodkin-Gal, Eitan Winter
Publikováno v:
Gut
ObjectiveCellular senescence limits tumourigenesis by blocking the proliferation of premalignant cells. Additionally, however, senescent cells can exert paracrine effects influencing tumour growth. Senescent cells are present in premalignant pancreat
Autor:
Julia Majewska, Amir Bar-Shai, Michael Tsoory, Raya Eilam, Adi Sagiv, Gal Manella, Naama Levi, Michel Tauc, Valery Krizhanovsky, Lior Zada, Sara W. Feigelson, Ezra Vadai, Ofer Regev, Miki Hatzav, Yossi Ovadya, Lior Roitman, Ronen Alon
Publikováno v:
Cell Reports
Cell Reports, Elsevier Inc, 2018, 22 (13), pp.3468-3479. ⟨10.1016/j.celrep.2018.03.009⟩
Cell Reports, Vol 22, Iss 13, Pp 3468-3479 (2018)
Cell Reports, Elsevier Inc, 2018, 22 (13), pp.3468-3479. ⟨10.1016/j.celrep.2018.03.009⟩
Cell Reports, Vol 22, Iss 13, Pp 3468-3479 (2018)
Summary: The tumor suppressor p53 limits tumorigenesis by inducing apoptosis, cell cycle arrest, and senescence. Although p53 is known to limit inflammation during tumor development, its role in regulating chronic lung inflammation is less well under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6fedf7033dd9f85494d1377527ccc4f
https://hal.archives-ouvertes.fr/hal-02918190
https://hal.archives-ouvertes.fr/hal-02918190
Autor:
Zoya Alteber, Dan Blat, Lior Roitman, Meirav Pevsner-Fischer, Adi Sharbi-Yunger, Eran Elinav, Lea Eisenbach, Esther Tzehoval
Publikováno v:
Immunology and cell biology. 96(3)
Inflammation plays pivotal roles in different stages of tumor development. Screening for predisposing genetic abnormalities and understanding the roles these genes play in the crosstalk between immune and cancer cells will provide new targets for can
Autor:
Lior Zada, Lior Roitman, Ziv Porat, Anat Biran, Ezra Vadai, Yossi Ovadya, Valery Krizhanovsky, Paula Abou Karam
Publikováno v:
Aging Cell
Summary Senescent cells are present in premalignant lesions and sites of tissue damage and accumulate in tissues with age. In vivo identification, quantification and characterization of senescent cells are challenging tasks that limit our understandi
Autor:
Shani Ben-Moshe, Immacolata Garzilli, Valery Krizhanovsky, Nili Dezorella, Lior Roitman, Lydia Farack, Beáta Tóth, Shalev Itzkovitz, Adi Egozi, Keren Bahar Halpern, Matan Golan
Publikováno v:
Developmental Cell. 48:115-125.e4
Pancreatic beta cells have been shown to be heterogeneous at multiple levels. However, spatially interrogating transcriptional heterogeneity in the intact tissue has been challenging. Here, we developed an optimized protocol for single-molecule trans
Autor:
Naama Levi, Nurit Papismadov, Julia Majewska, Lior Roitman, Noa Wigoda, Raya Eilam, Michael Tsoory, Ron Rotkopf, Yossi Ovadya, Hagay Akiva, Ofer Regev, Valery Krizhanovsky
Publikováno v:
Aging. 15(7):2395-2417