Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Lior Lobel"'
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT The microbiome plays a vital role in human health, with changes in its composition impacting various aspects of the body. Posttranslational modification (PTM) regulates protein activity by attaching chemical groups to amino acids in an enzym
Externí odkaz:
https://doaj.org/article/4c45acfaaf6942a984de2bed3fa9b2e1
Autor:
Andrew Goldstein, Yang Lei, Lena Goldstein, Amelia Goldstein, Qiao Xu Bai, Juan Felix, Roberta Lipson, Maria Demarco, Mark Schiffman, Didem Egemen, Kanan T. Desai, Sarah Bedell, Janet Gersten, Gail Goldstein, Karen O’Keefe, Casey O’Keefe, Tierney O’Keefe, Cathy Sebag, Lior Lobel, Anna Zhao, Yan Ling Lu
Publikováno v:
Infectious Agents and Cancer, Vol 15, Iss 1, Pp 1-7 (2020)
Abstract Objective Rapid, high-volume screening programs are needed as part of cervical cancer prevention in China. Methods In a 5-day screening project in Inner Mongolia, 3345 women volunteered following a community awareness campaign, and self-swab
Externí odkaz:
https://doaj.org/article/78d90dd307ef42cfbb87435f6ff8b54a
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007283 (2018)
Listeria monocytogenes (Lm) is a saprophyte and intracellular pathogen. Transition to the pathogenic state relies on sensing of host-derived metabolites, yet it remains unclear how these are recognized and how they mediate virulence gene regulation.
Externí odkaz:
https://doaj.org/article/ca273cf3755243a59e38422052e6d75d
Autor:
Adi Haber, Sivan Friedman, Lior Lobel, Tamar Burg-Golani, Nadejda Sigal, Jessica Rose, Nurit Livnat-Levanon, Oded Lewinson, Anat A Herskovits
Publikováno v:
PLoS Pathogens, Vol 13, Iss 1, p e1006161 (2017)
The high environmental adaptability of bacteria is contingent upon their ability to sense changes in their surroundings. Bacterial pathogen entry into host poses an abrupt and dramatic environmental change, during which successful pathogens gauge mul
Externí odkaz:
https://doaj.org/article/9520c67bc0ce429cb15117587b7ada60
Autor:
Lior Lobel, Anat A Herskovits
Publikováno v:
PLoS Genetics, Vol 12, Iss 2, p e1005870 (2016)
Bacteria sense and respond to many environmental cues, rewiring their regulatory network to facilitate adaptation to new conditions/niches. Global transcription factors that co-regulate multiple pathways simultaneously are essential to this regulator
Externí odkaz:
https://doaj.org/article/9bd3fc2a73cc49caa33ea3924958acc3
Publikováno v:
Bio-Protocol, Vol 5, Iss 22 (2015)
Studying the transcriptome of bacterial pathogens during infection is a very informative and effective tool for discovering genes that contribute to successful infection. However, isolating bacterial RNA from infected cells or tissues is a challengin
Externí odkaz:
https://doaj.org/article/f048672dadf84ea48ffbb96a43e5e54b
Publikováno v:
PLoS Genetics, Vol 8, Iss 9, p e1002887 (2012)
Intracellular bacterial pathogens are metabolically adapted to grow within mammalian cells. While these adaptations are fundamental to the ability to cause disease, we know little about the relationship between the pathogen's metabolism and virulence
Externí odkaz:
https://doaj.org/article/f6a1c1121c394a9fa0687958f5511477
Publikováno v:
Science
Microbiota protect the kidneys Chronic kidney disease (CKD) afflicts millions of people globally. The first-line treatment for CKD is dietary intervention, so there may be a gut microbiota–associated component. Lobel et al. investigated the mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9259649ffb9957242b438072b0716aa5
https://doi.org/10.1126/science.abb3763
https://doi.org/10.1126/science.abb3763
Autor:
Y. Grace Cao, Sena Bae, Jannely Villarreal, Madelyn Moy, Eunyoung Chun, Monia Michaud, Jessica K. Lang, Jonathan N. Glickman, Lior Lobel, Wendy S. Garrett
Publikováno v:
Cell hostmicrobe. 30(9)
The intestinal epithelium plays critical roles in sensing and integrating dietary and microbial signals. How microbiota and intestinal epithelial cell (IEC) interactions regulate host physiology in the proximal small intestine, particularly the duode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038dd4d633cee3767a61e114548fc540
https://pubmed.ncbi.nlm.nih.gov/35985335
https://pubmed.ncbi.nlm.nih.gov/35985335
Autor:
Lior Lobel, Wendy S. Garrett
Publikováno v:
Immunity. 50:275-278
Butyrate is a microbial metabolite with pleiotropic effects. Schulthess et al. (2019) report that butyrate preconditioning of macrophages enhances their anti-bacterial preparedness by inducing anti-microbial proteins that restrict bacterial growth. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0909380f9efa4f1020495d4df1e88278
https://doi.org/10.1016/j.immuni.2019.01.015
https://doi.org/10.1016/j.immuni.2019.01.015