Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Lior Lasman"'
Publikováno v:
Cell Reports, Vol 39, Iss 5, Pp 110778- (2022)
Summary: Antibody-mediated immunity is initiated by B cell differentiation into multiple cell subsets, including plasmablast, memory, and germinal center (GC) cells. B cell differentiation trajectories are determined by transcription factors, yet ver
Externí odkaz:
https://doaj.org/article/9fa46b5cfee64e97ac60ed32bfee3c0f
Publikováno v:
Epigenomes, Vol 4, Iss 1, p 5 (2020)
The rising field of RNA modifications is stimulating massive research nowadays. m6A, the most abundant mRNA modification is highly conserved during evolution. Through the last decade, the essential components of this dynamic mRNA modification machine
Externí odkaz:
https://doaj.org/article/27e8c06be80d43dcbdc4016ba03cad6d
Publikováno v:
Cell reports. 39(5)
Antibody-mediated immunity is initiated by B cell differentiation into multiple cell subsets, including plasmablast, memory, and germinal center (GC) cells. B cell differentiation trajectories are determined by transcription factors, yet very few mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063fd89b89b224a95f33746f640dfdf5
https://pubmed.ncbi.nlm.nih.gov/35508130
https://pubmed.ncbi.nlm.nih.gov/35508130
Autor:
Jacob H. Hanna, Xianyao Xu, Jop H. van Berlo, Lior Lasman, Lisa E. Dorn, Federica Accornero, Jing Chen, Thomas J. Hund, Mario Medvedovic
Publikováno v:
Circulation
Supplemental Digital Content is available in the text.
Background: N6-Methyladenosine (m6A) methylation is the most prevalent internal posttranscriptional modification on mammalian mRNA. The role of m6A mRNA methylation in the heart is not known
Background: N6-Methyladenosine (m6A) methylation is the most prevalent internal posttranscriptional modification on mammalian mRNA. The role of m6A mRNA methylation in the heart is not known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ecadb39e8280d2f52eb00201a06f7d
https://doi.org/10.1161/circulationaha.118.036146
https://doi.org/10.1161/circulationaha.118.036146
Autor:
Ella Gillis, Noam Stern-Ginossar, Mirko Trilling, Jacob H. Hanna, Modi Safra, Clara Soyris, Schraga Schwartz, Aharon Nachshon, Nehemya Friedman, Shay Geula, Roni Winkler, Lior Lasman, Michal Mandelboim, Vu Thuy Khanh Le-Trilling, Julie Tai-Schmiedel
Publikováno v:
Nature Immunology
N6-methyladenosine (m6A) is the most common mRNA modification. Recent studies have revealed that depletion of m6A machinery leads to alterations in the propagation of diverse viruses. These effects were proposed to be mediated through dysregulated me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0a75aa51573fd1b674429f6b7458e2c
https://doi.org/10.1038/s41590-018-0275-z
https://doi.org/10.1038/s41590-018-0275-z
Autor:
Daoud Sheban, Shahd Ashouokhi, Rada Massarwa, Sharon Slomovich, Yoseph Addadi, Hadas Keren-Shaul, Alejandro Aguilera-Castrejon, Noa Novershtern, Sergey Viukov, Yoach Rais, Jacob H. Hanna, Mirie Zerbib, Raanan Shlomo, Lior Lasman, Nir Livnat, Bernardo Oldak, Nadir Ghanem, Yonatan Stelzer, Valeriya Chugaeva, Shadi Tarazi, Itay Maza, Chen Itzkovich, Tom Shani, Jonathan Bayerl, Saifeng Cheng, Muneef Ayyash
Publikováno v:
Nature
The mammalian body plan is established shortly after the embryo implants into the maternal uterus, and our understanding of post-implantation developmental processes remains limited. Although pre- and peri-implantation mouse embryos are routinely cul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bbf74214d26a4d6b8c0800c472362f6
https://pubmed.ncbi.nlm.nih.gov/33731940
https://pubmed.ncbi.nlm.nih.gov/33731940
Autor:
Leehee Weinberger, Dalit Ben-Yosef, Rada Massarwa, Sergey Viukov, Shay Geula, Shahd Ashouokhi, Ohad Gafni, Hadar Amir, Yael Kalma, Alejandro Aguilera-Castrejon, Vladislav Krupalnik, Jacob H. Hanna, Noa Novershtern, Mirie Zerbib, Tom Shani, Segev Naveh Tassa, Muneef Ayyash, Jonathan Bayerl, Yair S. Manor, Emilie Wildschutz, Shadi Tawil, Daoud Sheban, Nir Livnat, Lior Lasman, Nofar Mor, Shadi Tarazi, Varda Rotter, Suhair Hanna, Bernardo Oldak
Publikováno v:
Cell Stem Cell
Summary Isolating human MEK/ERK signaling-independent pluripotent stem cells (PSCs) with naive pluripotency characteristics while maintaining differentiation competence and (epi)genetic integrity remains challenging. Here, we engineer reporter system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58483142ce464c44c83fe99989fc4865
https://pubmed.ncbi.nlm.nih.gov/33915080
https://pubmed.ncbi.nlm.nih.gov/33915080
Autor:
Sergey Viukov, Ohad Gafni, Shay Geula, Nofar Mor, Jacob H. Hanna, Alejandro Aguilera-Castrejon, Noa Novershtern, Shadi Tawil, Suhair Hanna, Lior Lasman, Shadi Tarazi, Yair S. Manor, Yael Kalma, Bernardo Oldak, Tom Shani, Krupalnik, Nir Livnat, Daoud Sheban, Leehee Weinberger, Jonathan Bayerl, Hadar Amir, Mirie Zerbib, Dalit Ben-Yosef, Muneef Ayyash
Different conditions have been devised to isolate MEK/ERK signalling independent human naïve pluripotent stem cells (PSCs) that are distinct from conventional primed PSCs and better correspond to pre-implantation developmental stages. While the naï
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f84b29ff33eed17405ea621010435d4b
https://doi.org/10.1101/2020.05.23.112433
https://doi.org/10.1101/2020.05.23.112433
Autor:
Lior, Lasman, Vladislav, Krupalnik, Sergey, Viukov, Nofar, Mor, Alejandro, Aguilera-Castrejon, Dan, Schneir, Jonathan, Bayerl, Orel, Mizrahi, Shani, Peles, Shadi, Tawil, Shashank, Sathe, Aharon, Nachshon, Tom, Shani, Mirie, Zerbib, Itay, Kilimnik, Stefan, Aigner, Archana, Shankar, Jasmine R, Mueller, Schraga, Schwartz, Noam, Stern-Ginossar, Gene W, Yeo, Shay, Geula, Noa, Novershtern, Jacob H, Hanna
Publikováno v:
Genes Dev
The N6-methyladenosine (m(6)A) modification is the most prevalent post-transcriptional mRNA modification, regulating mRNA decay and splicing. It plays a major role during normal development, differentiation, and disease progression. The modification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f343818417865a00f9437f62b8176ee
https://pubmed.ncbi.nlm.nih.gov/32943573
https://pubmed.ncbi.nlm.nih.gov/32943573
Publikováno v:
Epigenomes, Vol 4, Iss 1, p 5 (2020)
The rising field of RNA modifications is stimulating massive research nowadays. m6A, the most abundant mRNA modification is highly conserved during evolution. Through the last decade, the essential components of this dynamic mRNA modification machine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa907c692fdb651fe9d80809469bb5a1
https://www.mdpi.com/2075-4655/4/1/5
https://www.mdpi.com/2075-4655/4/1/5