PEPOP 2.0: new approaches to mimic non-continuous epitopes

Autor: Liza Felicori, Franck Molina, Benedicte Jardin, Alexandre G. de Brevern, Violaine Moreau, Lionel Valera, Géraldine Lavigne, Vincent Demolombe, Ricardo Andrez Machado De Ávila, Aurélien Lebreton, Christophe Nguyen

Publikováno v: BMC Bioinformatics
BMC Bioinformatics, BioMed Central, 2019, 20 (1), ⟨10.1186/s12859-019-2867-5⟩
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-14 (2019)
BMC Bioinformatics, 2019, 20 (1), ⟨10.1186/s12859-019-2867-5⟩

Background Bioinformatics methods are helpful to identify new molecules for diagnostic or therapeutic applications. For example, the use of peptides capable of mimicking binding sites has several benefits in replacing a protein which is difficult to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba880873a479f0eb0607d04645692203
https://hal.archives-ouvertes.fr/hal-02277257

Combining culture and microbead-based immunoassay for the early and generic detection of bacteria in platelet concentrates

Autor: Jeannette Fareh, Typhaine Dagland, Ludivine Vossier, Stéphanie Roche, Agnès Pouzet, Fanny Leon, Carole Farre, Christine Favier, Laetitia Rubrecht, Chantal Fournier-Wirth, Stéphane Rihet, Carole Chaix, Romaric Bonnet, Nicole Jaffrezic-Renault, Lionel Valera, Pascale Galea, Gaelle‐Anne Cremer, Dominique Piquer

Publikováno v: Transfusion
Transfusion, Wiley, 2019, 59 (1), pp.277-286. ⟨10.1111/trf.15019⟩

BACKGROUND Despite current preventive strategies, bacterial contamination of platelets is the highest residual infectious risk in transfusion. Bacteria can grow from an initial concentration of 0.03-0.3 colony-forming units (CFUs)/mL up to 108 to 109

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::833e20e87a9843ce96dcccc49d2e4335
https://hal.umontpellier.fr/hal-01934702

Antibody–antigenic peptide interactions monitored by SPR and QCM-D

Autor: Martine Pugnière, Françoise Roquet, Cédric Ayela, Claude Granier, Lionel Valera, Liviu Nicu

Publikováno v: Biosensors and Bioelectronics
Biosensors and Bioelectronics, Elsevier, 2007, 22 (12), pp.3113-3119. ⟨10.1016/j.bios.2007.01.020⟩

International audience; This work reports on a complementary use of surface plasmon resonance (SPR) and quartz crystal microbalance with dissipation monitoring (QCM-D) technologies to study interactions between a peptide antigen and polyclonal antibo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e30e2111e7bc676c98609a86bc5fba3
https://doi.org/10.1016/j.bios.2007.01.020

Proteomic demonstration of the recurrent presence of inter-alpha-inhibitor H4 heavy-chain during aspergillosis induced in an animal model

Autor: Sonia Hem, Bénédicte Cormier, Agnès Caille, Lionel Valera, E. Bailly, Bénédicte Jardin, Marie-Lise Jourdan, Patrice Diot, Jacques Chandenier, Sylvain Marchand-Adam, Guillaume Desoubeaux

Publikováno v: International journal of medical microbiology : IJMM
International journal of medical microbiology : IJMM, 2014, 304 (3-4), pp.327-38. ⟨10.1016/j.ijmm.2013.11.015⟩

International audience; Invasive pulmonary aspergillosis remains a matter of great concern in oncology/haematology, intensive care units and organ transplantation departments. Despite the availability of various diagnostic tools with attractive featu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b746289990198aa71b5a03b287e226c
https://hal.archives-ouvertes.fr/hal-01118314