Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Lionel Spinelli"'
Autor:
Rudy Aussel, Muhammad Asif, Sabrina Chenag, Sébastien Jaeger, Pierre Milpied, Lionel Spinelli
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Single-cell technologies have revolutionised biological research and applications. As they continue to evolve with multi-omics and spatial resolution, analysing single-cell datasets is becoming increasingly complex. For biologists lacking ex
Externí odkaz:
https://doaj.org/article/65d5944731514148b011c5306d696180
Autor:
Pierre de Langen, Fayrouz Hammal, Elise Guéret, Jean-Christophe Mouren, Lionel Spinelli, Benoit Ballester
Publikováno v:
Cell Genomics, Vol 3, Iss 10, Pp 100411- (2023)
Summary: Intergenic transcription in normal and cancerous tissues is pervasive but incompletely understood. To investigate this, we constructed an atlas of over 180,000 consensus RNA polymerase II (RNAPII)-bound intergenic regions from 900 RNAPII chr
Externí odkaz:
https://doaj.org/article/a67c6f08a05f4024b2322b9dd28ded25
Autor:
Saswati Saha, Lionel Spinelli, Jaime A Castro Mondragon, Anaïs Kervadec, Michaela Lynott, Laurent Kremmer, Laurence Roder, Sallouha Krifa, Magali Torres, Christine Brun, Georg Vogler, Rolf Bodmer, Alexandre R Colas, Karen Ocorr, Laurent Perrin
Publikováno v:
eLife, Vol 11 (2022)
Deciphering the genetic architecture of human cardiac disorders is of fundamental importance but their underlying complexity is a major hurdle. We investigated the natural variation of cardiac performance in the sequenced inbred lines of the Drosophi
Externí odkaz:
https://doaj.org/article/35f1c5c43e764e80af9403e2933094a5
Autor:
Pauline Brochet, Barbara Ianni, João P. S. Nunes, Amanda F. Frade, Priscila C. Teixeira, Charles Mady, Ludmila R. P. Ferreira, Andreia Kuramoto, Cristina W. Pissetti, Bruno Saba, Darlan D. S. Cândido, Fabrício Dias, Marcelo Sampaio, José A. Marin-Neto, Abílio Fragata, Ricardo C .F. Zaniratto, Sergio Siqueira, Giselle D. L. Peixoto, Vagner O. C. Rigaud, Paula Buck, Rafael R. Almeida, Hui Tzu Lin-Wang, André Schmidt, Martino Martinelli, Mario H. Hirata, Eduardo Donadi, Virmondes Rodrigues Junior, Alexandre C. Pereira, Jorge Kalil, Lionel Spinelli, Edecio Cunha-Neto, Christophe Chevillard
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chagas disease is a parasitic disease from South America, affecting around 7 million people worldwide. Decades after the infection, 30% of people develop chronic forms, including Chronic Chagas Cardiomyopathy (CCC), for which no treatment exists. Two
Externí odkaz:
https://doaj.org/article/bb254841467843829595af54d0de0b0a
Autor:
Pauline Brochet, Barbara Maria Ianni, Laurie Laugier, Amanda Farage Frade, João Paulo Silva Nunes, Priscila Camillo Teixeira, Charles Mady, Ludmila Rodrigues Pinto Ferreira, Quentin Ferré, Ronaldo Honorato Barros Santos, Andreia Kuramoto, Sandrine Cabantous, Samuel Steffen, Antonio Noedir Stolf, Pablo Pomerantzeff, Alfredo Inacio Fiorelli, Edimar Alcides Bocchi, Cristina Wide Pissetti, Bruno Saba, Darlan da Silva Cândido, Fabrício C. Dias, Marcelo Ferraz Sampaio, Fabio Antônio Gaiotto, José Antonio Marin-Neto, Abílio Fragata, Ricardo Costa Fernandes Zaniratto, Sergio Siqueira, Giselle De Lima Peixoto, Vagner Oliveira-Carvalho Rigaud, Fernando Bacal, Paula Buck, Rafael Ribeiro Almeida, Hui Tzu Lin-Wang, André Schmidt, Martino Martinelli, Mario Hiroyuki Hirata, Eduardo Antonio Donadi, Alexandre Costa Pereira, Virmondes Rodrigues Junior, Denis Puthier, Jorge Kalil, Lionel Spinelli, Edecio Cunha-Neto, Christophe Chevillard
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chagas disease, caused by the protozoan Trypanosoma cruzi, is an endemic parasitic disease of Latin America, affecting 7 million people. Although most patients are asymptomatic, 30% develop complications, including the often-fatal Chronic Chagasic Ca
Externí odkaz:
https://doaj.org/article/65fdda843b04496390e425c5897c4f93
Autor:
Margaux Vienne, Marion Etiennot, Bertrand Escalière, Justine Galluso, Lionel Spinelli, Sophie Guia, Aurore Fenis, Eric Vivier, Yann M. Kerdiles
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Natural killer (NK) cells are known to be able to kill established tumor cell lines, but important caveats remain regarding their roles in the detection and elimination of developing primary tumors. Using a genetic model of selective ILC1 and NK cell
Externí odkaz:
https://doaj.org/article/5d93b170ef1f4e6eba648775277a2912
Autor:
Noudjoud Attaf, Iñaki Cervera-Marzal, Chuang Dong, Laurine Gil, Amédée Renand, Lionel Spinelli, Pierre Milpied
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/59cc7bada5b74807a0c39ee8b9db2ce7
Autor:
Milesa Simic, Iris Manosalva, Lionel Spinelli, Rebecca Gentek, Raheleh R. Shayan, Carole Siret, Mathilde Girard-Madoux, Shuaiwei Wang, Lauriane de Fabritus, Janneke Verschoor, Yann M. Kerdiles, Marc Bajenoff, Ralf Stumm, Rachel Golub, Serge A. van de Pavert
Publikováno v:
Cell Reports, Vol 32, Iss 6, Pp 108004- (2020)
Summary: During embryogenesis, lymphoid tissue inducer (LTi) cells are essential for lymph node organogenesis. These cells are part of the innate lymphoid cell (ILC) family. Although their earliest embryonic hematopoietic origin is unclear, other inn
Externí odkaz:
https://doaj.org/article/976572a732984708aeedd98df1083eeb
Autor:
Camille Wagner, Johnny Bonnardel, Clément Da Silva, Lionel Spinelli, Cynthia Arroyo Portilla, Julie Tomas, Margaux Lagier, Lionel Chasson, Marion Masse, Marc Dalod, Alexandre Chollat-Namy, Jean-Pierre Gorvel, Hugues Lelouard
Publikováno v:
Cell Reports, Vol 31, Iss 1, Pp - (2020)
Summary: The monocyte-derived phagocytes termed LysoDCs are hallmarks of Peyer’s patches, where their main function is to sample intestinal microorganisms. Here, we study their differentiation pathways in relation with their sampling, migratory, an
Externí odkaz:
https://doaj.org/article/6a3f915947a14b7c93ab93f7f0f6f573
Autor:
Noudjoud Attaf, Iñaki Cervera-Marzal, Chuang Dong, Laurine Gil, Amédée Renand, Lionel Spinelli, Pierre Milpied
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Single-cell RNA sequencing (scRNA-seq) allows the identification, characterization, and quantification of cell types in a tissue. When focused on B and T cells of the adaptive immune system, scRNA-seq carries the potential to track the clonal lineage
Externí odkaz:
https://doaj.org/article/94ed25d0d5a54e5785b11adb5093b187