Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Lionel Mercier"'
Autor:
Angelo Paci, Ségolène Hescot, Atmane Seck, Christel Jublanc, Lionel Mercier, Delphine Vezzosi, Delphine Drui, Marcus Quinkler, Martin Fassnacht, Eric Bruckert, Marc Lombès, Sophie Leboulleux, Sophie Broutin, Eric Baudin
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Pp 1-4 (2016)
Mitotane (o,p′-DDD) is the standard treatment for advanced adrenocortical carcinoma (ACC). Monitoring of plasma mitotane levels is recommended to look for a therapeutic window between 14 and 20mg/L, but its positive predictive value requires optimi
Externí odkaz:
https://doaj.org/article/fcc16fee6df7425e933211f6f87f4929
Publikováno v:
Journal of Chromatography B. 1189:123085
The hallmarks of cancer include metabolism with deregulating cellular energetics. Dysfunctions in succinate dehydrogenase (SDH) metabolic enzyme activity, leading to an abnormal accumulation of succinic acid has been described in solid tumors but als
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928961e0b7eb93bf0adab1feb89e68b0
https://doi.org/10.1016/j.jchromb.2021.123085
https://doi.org/10.1016/j.jchromb.2021.123085
Autor:
François Lemare, Lionel Mercier, Angelo Paci, Diane Goéré, David Malka, Valérie Boige, Michel Ducreux, Sophie Broutin, Dominique Elias, Fanny Jaulin, Charlotte Canet-Jourdan, M. Annereau, Olivier Zajac, P. Roy, Maximiliano Gelli
Publikováno v:
International Journal of Pharmaceutics. 531:143-152
Background Peritoneal metastases (PM), corresponding to tumor implants into the peritoneal cavity, are associated with impaired prognosis and low responsiveness to systemic chemotherapy. A new therapeutic approach has dramatically changed the prognos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::714f449db06f6dfddf18e11073a0b885
https://doi.org/10.1016/j.ijpharm.2017.07.084
https://doi.org/10.1016/j.ijpharm.2017.07.084
Autor:
Lionel Mercier, Alain Deroussent, Fabienne Munier, Clémentine Richard, Dominique Valteau-Couanet, Angelo Paci, Gilles Vassal, Bassim Tou, Jérôme Bouligand, Cedric Orear, Paule Opolon, Romain Kessari, Nicolas Simonnard, Estelle Daudigeos-Dubus
Publikováno v:
Pharmaceutical Research. 33:1913-1922
Busulfan-melphalan high-dose chemotherapy followed by autologous stem cell transplantation is an essential consolidation treatment of high-risk neuroblastoma in children. Main treatment limitation is hepatic veno-occlusive disease, the most severe an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a1d1d66c93c629301c3c4e7029ff176
https://doi.org/10.1007/s11095-016-1927-z
https://doi.org/10.1007/s11095-016-1927-z
Autor:
Dorian Bailleux, Sophie Broutin, Angelo Paci, Ségolène Hescot, Constance Lamy, Julien Hadoux, Lionel Mercier, Eric Baudin
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52363deb512df944fd56d6fe5c119035
https://doi.org/10.1530/endoabs.49.ep179
https://doi.org/10.1530/endoabs.49.ep179
Autor:
Christel Jublanc, Sophie Leboulleux, Marc Lombès, Angelo Paci, Eric Baudin, Martin Fassnacht, Marcus Quinkler, Delphine Drui, Delphine Vezzosi, Ségolène Hescot, Eric Bruckert, Atmane Seck, Sophie Broutin, Lionel Mercier
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports
Endocrinology, Diabetes & Metabolism Case Reports, Pp 1-4 (2016)
Endocrinology, Diabetes & Metabolism Case Reports, Pp 1-4 (2016)
Mitotane (o,p′-DDD) is the standard treatment for advanced adrenocortical carcinoma (ACC). Monitoring of plasma mitotane levels is recommended to look for a therapeutic window between 14 and 20mg/L, but its positive predictive value requires optimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e8af2de5d2c050636b762632a3633d
https://doi.org/10.1530/edm-15-0135
https://doi.org/10.1530/edm-15-0135
Autor:
Thierry Martens, Angelo Paci, Micheline Re, Philippe Bourget, Elise Prost, Gilles Vassal, Lionel Mercier, Jacques Royer, Alain Deroussent, Fabienne Munier, Thomas Storme
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 328:598-609
Ifosfamide is a well known prodrug for cancer treatment with cytochrome P450 metabolism. It is associated with both antitumor activity and toxicities. Isophosphoramide mustard is the bisalkylating active metabolite, and acrolein is a urotoxic side pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260bcaf502969b0e40bc9b81950f11d0
https://doi.org/10.1124/jpet.108.144170
https://doi.org/10.1124/jpet.108.144170
Publikováno v:
Drugs in R&D
Melphalan is an alkylating agent frequently used in an intravenous formulation to treat hematologic malignancies and solid tumors in both adults and children. According to the manufacturer, melphalan is stable in sterile 0.9 % sodium chloride for 90
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b99637d93278d2be61be5a4206b559f5
https://pubmed.ncbi.nlm.nih.gov/26178037
https://pubmed.ncbi.nlm.nih.gov/26178037
Autor:
Micheline Re, Angelo Paci, Philippe Bourget, Lionel Mercier, Jacques Royer, Thierry Martens, Thomas Storme, Alain Deroussent, Gilles Vassal
Publikováno v:
Journal of Chromatography B. 820:251-259
A specific and sensitive quantitative assay has been developed using high performance liquid chromatography–electrospray ionization mass spectrometry (HPLC–ESI-MS) for the simultaneous quantitation of the antitumor drug ifosfamide (IFM) and its t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab860c729ccc96f231ff7270f1986c9e
https://doi.org/10.1016/j.jchromb.2005.03.023
https://doi.org/10.1016/j.jchromb.2005.03.023
Publikováno v:
Pathologie Biologie. 53:210-216
Morphine and meperidine in Patient-Controlled Analgesic devices are commonly used to treat chronic pain patients. These devices deliver a programmed amount of drug and allow self-administration by the patient depending on the pain. In our department
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72226ff8d0be2d24e5beadeea0cf9e52
https://doi.org/10.1016/j.patbio.2004.09.007
https://doi.org/10.1016/j.patbio.2004.09.007