Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lionel M L Chow"'
Publikováno v:
PLoS Biology, Vol 8, Iss 8, p e1000460 (2010)
The dentate gyrus has an important role in learning and memory, and adult neurogenesis in the subgranular zone of the dentate gyrus may play a role in the acquisition of new memories. The homeobox gene Prox1 is expressed in the dentate gyrus during e
Externí odkaz:
https://doaj.org/article/57c9cb1263cf4293b874d7b7bff145b3
Autor:
Elizabeth Gilger, Mariko DeWire, Wanda Meriwether, Shiva Senthil Kumar, Dinah Meister, Maureen Gallagher, Trent R. Hummel, Lori Driver, Anthony Asher, Christine Fuller, Natasha Pillay-Smiley, Lindsey Hoffman, Rachid Drissi, Susan Jelinek, Ralph Salloum, Blaise V. Jones, James L. Leach, Lionel M L Chow, Peter de Blank, Satarupa Sengupta, Maryam Fouladi, Heather Ward, Bridget Kikta, Lili Miles, Craig Erker
Publikováno v:
Journal of Neuro-Oncology. 152:107-114
While autopsy-repository programs with a variety of pediatric central nervous system (CNS) tumor types are a critical resource for preclinical neuro-oncology research, few exist and there is no published guidance on how to develop one. The goal of th
Autor:
Blaise V. Jones, Luke Pater, Adam Lane, Trent R. Hummel, Shiva Senthil Kumar, Adam C. Carle, Ralph Salloum, James L. Leach, Phil Dexheimer, Christine Fuller, Charles B. Stevenson, David P. Witte, Maryam Fouladi, Mariko DeWire, Rachid Drissi, Sarah A. Lawson, Lionel M L Chow, Peter de Blank, John C. Breneman, Xiaoting Zhu
Publikováno v:
Journal of Neuro-Oncology. 149:511-522
Cyclin-dependent kinase-retinoblastoma (CDK-RB) pathway is dysregulated in some diffuse intrinsic pontine gliomas (DIPG). We evaluated safety, feasibility, and early efficacy of the CDK4/6-inhibitor ribociclib, administered following radiotherapy in
Autor:
Jackson Neal Howell, Lionel M L Chow, Christopher E. Dandoy, Mukund Dole, Kambiz Kamian, Ralph E. Vatner, Jordan M Wright, Ayman El-Sheikh
Publikováno v:
Cancer Reports. 5
Background Intracranial germ cell tumors (GCTs) comprise 3%-5% of pediatric primary central nervous system (CNS) tumors in Western countries. Though they are related in embryonic origin to gonadal GCTs, which are considered highly treatable with cisp
Autor:
Mariko, DeWire, Craig, Erker, Trent R, Hummel, Lionel M L, Chow, Peter, de Blank, Ralph, Salloum, Natasha, Pillay-Smiley, Lindsey, Hoffman, Elizabeth, Gilger, Maureen, Gallagher, Lori, Driver, Dinah, Meister, Heather, Ward, Rachid, Drissi, Shiva Senthil, Kumar, Satarupa, Sengupta, Bridget, Kikta, Wanda, Meriwether, Susan, Jelinek, Anthony, Asher, Blaise, Jones, James, Leach, Lili, Miles, Christine, Fuller, Maryam, Fouladi
Publikováno v:
Journal of neuro-oncology. 152(1)
While autopsy-repository programs with a variety of pediatric central nervous system (CNS) tumor types are a critical resource for preclinical neuro-oncology research, few exist and there is no published guidance on how to develop one. The goal of th
Autor:
Mariko, DeWire, Christine, Fuller, Trent R, Hummel, Lionel M L, Chow, Ralph, Salloum, Peter, de Blank, Luke, Pater, Sarah, Lawson, Xiaoting, Zhu, Phil, Dexheimer, Adam C, Carle, Shiva Senthil, Kumar, Rachid, Drissi, Charles B, Stevenson, Adam, Lane, John, Breneman, David, Witte, Blaise V, Jones, James L, Leach, Maryam, Fouladi
Publikováno v:
Journal of neuro-oncology. 149(3)
Cyclin-dependent kinase-retinoblastoma (CDK-RB) pathway is dysregulated in some diffuse intrinsic pontine gliomas (DIPG). We evaluated safety, feasibility, and early efficacy of the CDK4/6-inhibitor ribociclib, administered following radiotherapy in
Autor:
Diana Nardini, Mohammad Alfrad Nobel Bhuiyan, Stefanie Schirmeier, Ranjithmenon Muraleedharan, Nicole Oatman, Raghavendra Rao, Ronald R. Waclaw, Abitha Sukumaran, Jane Anderson, Amber L. Ward, Ivan Tkáč, Christina Gross, Biplab Dasgupta, Lionel M L Chow, Mondira Kundu, Mruniya V. Gawali, Deepak Tiwari
Publikováno v:
Cell reports. 32(9)
Summary Lactate is used as an energy source by producer cells or shuttled to neighboring cells and tissues. Both glucose and lactate fulfill the bioenergetic demand of neurons, the latter imported from astrocytes. The contribution of astrocytic lacta
Autor:
Ralph Salloum, Melissa K. McConechy, Leonie G. Mikael, Christine Fuller, Rachid Drissi, Mariko DeWire, Hamid Nikbakht, Nicolas De Jay, Xiaodan Yang, Daniel Boue, Lionel M. L. Chow, Jonathan L. Finlay, Tenzin Gayden, Jason Karamchandani, Trent R. Hummel, Randal Olshefski, Diana S. Osorio, Charles Stevenson, Claudia L. Kleinman, Jacek Majewski, Maryam Fouladi, Nada Jabado
Publikováno v:
Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-12 (2017)
Abstract Pediatric high-grade gliomas (pHGGs) are aggressive neoplasms representing approximately 20% of brain tumors in children. Current therapies offer limited disease control, and patients have a poor prognosis. Empiric use of targeted therapy, e
Externí odkaz:
https://doaj.org/article/833c658027c5472dad6ddac83cfab32a