Výsledky vyhledávání - "Lionel Hoffmann"

Akademický článek

Knowledge-based prediction of protein backbone conformation using a structural alphabet.

Autor: Iyanar Vetrivel, Swapnil Mahajan, Manoj Tyagi, Lionel Hoffmann, Yves-Henri Sanejouand, Narayanaswamy Srinivasan, Alexandre G de Brevern, Frédéric Cadet, Bernard Offmann

Publikováno v: PLoS ONE, Vol 12, Iss 11, p e0186215 (2017)

Libraries of structural prototypes that abstract protein local structures are known as structural alphabets and have proven to be very useful in various aspects of protein structure analyses and predictions. One such library, Protein Blocks, is compo

Externí odkaz: https://doaj.org/article/2924e17e0d9d4efb95c61b0628a99976

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PB-kPRED: knowledge-based prediction of protein backbone conformation using a structural alphabet

Autor: Swapnil Mahajan, Bernard Offmann, Alexandre G. de Brevern, Lionel Hoffmann, Manoj Tyagi, Iyanar Vetrivel, Yves-Henri Sanejouand, Frédéric Cadet, Narayanaswamy Srinivasan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576f765a7b38d06672de8e4d74a68712

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Rational design of a GH1 -glycosidase to prevent self-condensation during the transglycosylation reaction

Autor: Charles Tellier, Lionel Hoffmann, Vinh Tran, Claude Rabiller, Michel Dion

Publikováno v: Protein Engineering Design and Selection. 23:43-49

Mutant N282T of a thermostable beta-glycosidase from GH1 family (TtbetaGly) presenting a high transglycosidase activity was previously obtained by directed evolution. However, it displays a self-condensation activity with the donor 2-nitrophenyl-beta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe4995ed63bf34b5fb731b68a04d59c3
https://doi.org/10.1093/protein/gzp068

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Optimization of the Driver of GaN Power Transistors Through Measurement of Their Thermal Behavior

Autor: Cyrille Gautier, Stéphane Lefebvre, Lionel Hoffmann, Francois Costa

Publikováno v: IEEE Transactions on Power Electronics
IEEE Transactions on Power Electronics, Institute of Electrical and Electronics Engineers, 2014, 29 (5), pp.2359-2366. ⟨10.1109/TPEL.2013.2277759⟩

GaN field effect power transistors based on Si substrate show low on-state resistance and very small Cgs capacitance. Therefore these devices are good candidates for high-frequency switching operation. In this paper, we first focus on reverse conduct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ede4e46fbc83e5b950ec609a28be7e2
https://hal.archives-ouvertes.fr/hal-01686023

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Thermal measurement of losses of GaN power transistors for optimization of their drive

Autor: Lionel Hoffmann, Cyrille Gautier, Francois Costa, Stéphane Lefebvre

Publikováno v: Power Electronics and Applications (EPE)
Power Electronics and Applications (EPE), 2013, Lille, France

In this paper, we present a thermal measurement method of the losses of eGaN-FET power transistor used in one phase leg. The dead-times are important to avoid short-circuit phase, but they can lead to a large part of the total losses because of rever

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e27744f2ff29ac5badee8422c0fa1f8
https://hal.science/hal-01700482

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Converting a {beta}-glycosidase into a {beta}-transglycosidase by directed evolution

Autor: Charles Tellier, Vinh Tran, Lionel Hoffmann, Hui Yong Feng, Michel Dion, Jullien Drone, Claude Rabiller

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2005, 280 (44), pp.37088-37097. ⟨10.1074/jbc.M502873200⟩

International audience; Directed evolution was applied to the beta-glycosidase of Thermus thermophilus in order to increase its ability to synthesize oligosaccharide by transglycosylation. Wild-type enzyme was able to transfer the glycosyl residue wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43dc12833f69059fb428d8c2f3e2d509
https://pubmed.ncbi.nlm.nih.gov/16085651

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Bivalent Fv antibody fragments obtained by substituting the constant domains of a fab fragment with heterotetrameric molybdopterin synthase

Autor: Charles Tellier, Alain Defontaine, Lionel Hoffmann, Michel Dion, Kliment Petrov, Thierry Dintinger

Publikováno v: Journal of molecular biology. 341(4)

The antibody Fv fragment is the smallest functional unit of an antibody but for practical use, the VH/VL interface requires stabilization, which is usually accomplished by a peptide linker that joins the two variable domains to form a single chain Fv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::197c326a3f4c16687165daff39936635
https://pubmed.ncbi.nlm.nih.gov/15328616

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Cover Picture:Thermus thermophilus Glycosynthases for the Efficient Synthesis of Galactosyl and Glucosyl β-(1→3)-Glycosides (Eur. J. Org. Chem. 10/2005)

Autor: Claude Rabiller, Hui-yong Feng, V.H. Tran, Lionel Hoffmann, Charles Tellier, Jullien Drone, Michel Dion

Publikováno v: European Journal of Organic Chemistry. 2005:1939-1939

The cover picture shows the molecular modeling of the active site of a “glycosynthase” mutant obtained by directed mutagenesis (E338S) of the native thermostable Tt-β-Glyglycosidase from Thermus thermophilus. The relative orientations of the don

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::00d8cda13a9b890c72b71d2f55cd9ccb
https://doi.org/10.1002/ejoc.200590020

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Akademický článek

Graphical Abstract: Eur. J. Org. Chem. 10/2005.

Autor: Jullien Drone, Hui-yong Feng, Charles Tellier, Lionel Hoffmann, Vinh Tran, Claude Rabiller, Michel Dion

Publikováno v: European Journal of Organic Chemistry; May2005, Vol. 2005 Issue 10, p1939-1944, 6p

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