Zobrazeno 1 - 10
of 171
pro vyhledávání: '"Lionel Feigenbaum"'
Autor:
Sebastian A. Stifter, Nayan Bhattacharyya, Andrew J. Sawyer, Taylor A. Cootes, John Stambas, Sean E. Doyle, Lionel Feigenbaum, William E. Paul, Warwick J. Britton, Alan Sher, Carl G. Feng
Publikováno v:
Cell Reports, Vol 29, Iss 11, Pp 3539-3550.e4 (2019)
Summary: Interferons (IFN) are pleiotropic cytokines essential for defense against infection, but the identity and tissue distribution of IFN-responsive cells in vivo are poorly defined. In this study, we generate a mouse strain capable of reporting
Externí odkaz:
https://doaj.org/article/15e874e4ab5a493a85ab24a4dd2c911b
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118311 (2015)
Members of the SNARE-family of proteins are known to be key regulators of the membrane-membrane fusion events required for intracellular membrane traffic. The ubiquitously expressed SNARE protein SNAP-23 regulates a wide variety of exocytosis events
Externí odkaz:
https://doaj.org/article/5537ecb60e504e03becd270f58b1ee25
Autor:
Chi-Ping Day, John Carter, Zoe Weaver Ohler, Carrie Bonomi, Rajaa El Meskini, Philip Martin, Cari Graff-Cherry, Lionel Feigenbaum, Thomas Tüting, Terry Van Dyke, Melinda Hollingshead, Glenn Merlino
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e109956 (2014)
Preclinical therapeutic assessment currently relies on the growth response of established human cell lines xenografted into immunocompromised mice, a strategy that is generally not predictive of clinical outcomes. Immunocompetent genetically engineer
Externí odkaz:
https://doaj.org/article/407bcab1b6514aee992962f4d3e4de0f
Autor:
Renata I Mazzucchelli, Søren Warming, Scott M Lawrence, Masaru Ishii, Mehrnoosh Abshari, A Valance Washington, Lionel Feigenbaum, Andrew C Warner, Davis J Sims, Wen Qing Li, Julie A Hixon, Daniel H D Gray, Benjamin E Rich, Matthew Morrow, Miriam R Anver, James Cherry, Dieter Naf, Lawrence R Sternberg, Daniel W McVicar, Andrew G Farr, Ronald N Germain, Keith Rogers, Nancy A Jenkins, Neal G Copeland, Scott K Durum
Publikováno v:
PLoS ONE, Vol 4, Iss 11, p e7637 (2009)
Interleukin-7 (IL-7) is required for lymphocyte development and homeostasis although the actual sites of IL-7 production have never been clearly identified. We produced a bacterial artificial chromosome (BAC) transgenic mouse expressing ECFP in the I
Externí odkaz:
https://doaj.org/article/97899add48644baaaae8623b3d0db253
Autor:
Patricia S. Steeg, Quentin R. Smith, Victoria M. Richon, Paul S. Meltzer, Kevin Camphausen, Seth M. Steinberg, Lionel Feigenbaum, Julie L. Bronder, Robert Walker, John F. Reilly, Sean Davis, David J. Liewehr, Helen R. Thorsheim, Kaci A. Bohn, Julie A. Gaasch, Rajendar K. Mittapalli, Vinay Rudraraju, Kunal S. Taskar, Eleazar Vega-Valle, Yongzhen Qian, Natasha Flores, Matthew Johnson, Elizabeth Hargrave, Jeanne Herring, Emily Hua, Fancy C. Thomas, Paul R. Lockman, Diane Palmieri
Supplementary Data from Vorinostat Inhibits Brain Metastatic Colonization in a Model of Triple-Negative Breast Cancer and Induces DNA Double-Strand Breaks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb52a8f4188c013d1c59ec946907de1c
https://doi.org/10.1158/1078-0432.22440621.v1
https://doi.org/10.1158/1078-0432.22440621.v1
Autor:
Patricia S. Steeg, Quentin R. Smith, Victoria M. Richon, Paul S. Meltzer, Kevin Camphausen, Seth M. Steinberg, Lionel Feigenbaum, Julie L. Bronder, Robert Walker, John F. Reilly, Sean Davis, David J. Liewehr, Helen R. Thorsheim, Kaci A. Bohn, Julie A. Gaasch, Rajendar K. Mittapalli, Vinay Rudraraju, Kunal S. Taskar, Eleazar Vega-Valle, Yongzhen Qian, Natasha Flores, Matthew Johnson, Elizabeth Hargrave, Jeanne Herring, Emily Hua, Fancy C. Thomas, Paul R. Lockman, Diane Palmieri
Purpose: As chemotherapy and molecular therapy improve the systemic survival of breast cancer patients, the incidence of brain metastases increases. Few therapeutic strategies exist for the treatment of brain metastases because the blood-brain barrie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c66b23241e3460ce2a7a894a329269
https://doi.org/10.1158/1078-0432.c.6517923.v1
https://doi.org/10.1158/1078-0432.c.6517923.v1
Autor:
Saraswati Sukumar, Manfred Gessler, Goran Landberg, Pedram Argani, Alan Rein, Lionel Feigenbaum, David L. Huso, Scott Kominsky, Soonweng Cho, Weiwen Teo, Preethi Korangath, Nguyen K. Nguyen, Adam Diehl, Liangfeng Han
Supplementary Figure Legends. Legend for Supplementary Figures S1-S10.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e0f2aad85fe4d577e73d9a3a7b9bc17
https://doi.org/10.1158/0008-5472.22403532.v1
https://doi.org/10.1158/0008-5472.22403532.v1
Autor:
Siegfried Janz, Georg-Wilhelm Bornkamm, Lionel Feigenbaum, Sharon H. Jackson, Walter Pretsch, Axel Polack, Klaus Felix
Supplementary Figure 2 from Moderate Hypermutability of a Transgenic lacZ Reporter Gene in Myc-Dependent Inflammation-Induced Plasma Cell Tumors in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8e2402a0024bf5978c48929c083716
https://doi.org/10.1158/0008-5472.22363239
https://doi.org/10.1158/0008-5472.22363239
Autor:
Patricia S. Steeg, Kenneth Aldape, Seth M. Steinberg, Alexander O. Vortmeyer, Douglas Halverson, Lionel Feigenbaum, Eleazar Vega-Valle, Raffael Kurek, Andreas M. Stark, Robert J. Weil, Toshiyuki Yoneda, Jeanne M. Herring, Julie L. Bronder, Diane Palmieri
Retrospective studies of breast cancer patients suggest that primary tumor Her-2 overexpression or trastuzumab therapy is associated with a devastating complication: the development of central nervous system (brain) metastases. Herein, we present Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc30fe7126bf8d9994d2c55a691ecbf
https://doi.org/10.1158/0008-5472.c.6495572
https://doi.org/10.1158/0008-5472.c.6495572
Autor:
Siegfried Janz, Georg-Wilhelm Bornkamm, Lionel Feigenbaum, Sharon H. Jackson, Walter Pretsch, Axel Polack, Klaus Felix
Mutator phenotypes, a common and largely unexplained attribute of human cancer, might be better understood in mouse tumors containing reporter genes for accurate mutation enumeration and analysis. Previous work on peritoneal plasmacytomas (PCTs) in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a61bd87cafa7579f09460f47f7eca44
https://doi.org/10.1158/0008-5472.c.6493617.v1
https://doi.org/10.1158/0008-5472.c.6493617.v1