Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Lionel Chasson"'
Autor:
Rémy Char, Zhuangzhuang Liu, Cédric Jacqueline, Marion Davieau, Maria-Graciela Delgado, Clara Soufflet, Mathieu Fallet, Lionel Chasson, Raphael Chapuy, Voahirana Camosseto, Eva Strock, Rejane Rua, Catarina R. Almeida, Bing Su, Ana-Maria Lennon-Duménil, Beatrice Nal, Antoine Roquilly, Yinming Liang, Stéphane Méresse, Evelina Gatti, Philippe Pierre
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Endo-lysosomes transport along microtubules and clustering in the perinuclear area are two necessary steps for microbes to activate specialized phagocyte functions. We report that RUN and FYVE domain-containing protein 3 (RUFY3) exists as tw
Externí odkaz:
https://doaj.org/article/4a23f4a1b15044b5bbac175e040f08dd
Autor:
Fanny Hidalgo-Villeda, Matthieu Million, Catherine Defoort, Thomas Vannier, Ljubica Svilar, Margaux Lagier, Camille Wagner, Cynthia Arroyo-Portilla, Lionel Chasson, Cécilia Luciani, Vincent Bossi, Jean-Pierre Gorvel, Hugues Lelouard, Julie Tomas
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106910- (2023)
Summary: Severe acute malnutrition (SAM) is a multifactorial disease affecting millions of children worldwide. It is associated with changes in intestinal physiology, microbiota, and mucosal immunity, emphasizing the need for multidisciplinary studie
Externí odkaz:
https://doaj.org/article/9d27926a3f9848cda104cdfe1687c3c9
Autor:
Franca Cassol, Loriane Portal, Sylvie Richelme, Mathieu Dupont, Yannick Boursier, Maria Arechederra, Nathalie Auphan-Anezin, Lionel Chasson, Caroline Laprie, Samantha Fernandez, Laure Balasse, Fabienne Lamballe, Rosanna Dono, Benjamin Guillet, Toby Lawrence, Christian Morel, Flavio Maina
Publikováno v:
iScience, Vol 21, Iss , Pp 68-83 (2019)
Summary: Computed tomography is a powerful medical imaging modality for longitudinal studies in cancer to follow neoplasia progression and evaluate anticancer therapies. Here, we report the generation of a photon-counting micro-computed tomography (P
Externí odkaz:
https://doaj.org/article/4ac8f497746640ab8599f6ebf470943e
Autor:
Yawen Wang, Annie Roussel-Queval, Lionel Chasson, Noël Hanna Kazazian, Laetitia Marcadet, Andrianos Nezos, Michael H. Sieweke, Clio Mavragani, Lena Alexopoulou
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Sjögren’s syndrome (SS) is a chronic systemic autoimmune disease that affects predominately salivary and lacrimal glands. SS can occur alone or in combination with another autoimmune disease like systemic lupus erythematosus (SLE). Here we report
Externí odkaz:
https://doaj.org/article/2d28ee07e9084d638891e84f4fbea5d4
Autor:
Camille Wagner, Johnny Bonnardel, Clément Da Silva, Lionel Spinelli, Cynthia Arroyo Portilla, Julie Tomas, Margaux Lagier, Lionel Chasson, Marion Masse, Marc Dalod, Alexandre Chollat-Namy, Jean-Pierre Gorvel, Hugues Lelouard
Publikováno v:
Cell Reports, Vol 31, Iss 1, Pp - (2020)
Summary: The monocyte-derived phagocytes termed LysoDCs are hallmarks of Peyer’s patches, where their main function is to sample intestinal microorganisms. Here, we study their differentiation pathways in relation with their sampling, migratory, an
Externí odkaz:
https://doaj.org/article/6a3f915947a14b7c93ab93f7f0f6f573
Autor:
Mohamed Habbeddine, Christophe Verthuy, Olivia Rastoin, Lionel Chasson, Magali Bebien, Marc Bajenoff, Sahil Adriouch, Joke M.M. den Haan, Josef M. Penninger, Toby Lawrence
Publikováno v:
Cell Reports, Vol 21, Iss 9, Pp 2515-2527 (2017)
The spleen plays an important role in protective immunity to bloodborne pathogens. Macrophages and dendritic cells (DCs) in the spleen marginal zone capture microbial antigens to trigger adaptive immune responses. Marginal zone macrophages (MZMs) can
Externí odkaz:
https://doaj.org/article/705661bb2792462fb2dbd272b8be592d
Autor:
Noël Hanna Kazazian, Yawen Wang, Annie Roussel-Queval, Laetitia Marcadet, Lionel Chasson, Caroline Laprie, Benoit Desnues, Jonathan Charaix, Magali Irla, Lena Alexopoulou
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Systemic lupus erythematosus (SLE) patients have increased prevalence of metabolic syndrome but the underlying mechanisms are unknown. Toll-like receptor 7 (TLR7) that detects single stranded-RNA plays a key role in antimicrobial host defense and als
Externí odkaz:
https://doaj.org/article/62e639586e6642d9826e0bc9a4b30bd9
Autor:
Marielle Balzano, Maria De Grandis, Thien-Phong Vu Manh, Lionel Chasson, Florence Bardin, Anne Farina, Arnauld Sergé, Ghislain Bidaut, Pierre Charbord, Léonard Hérault, Anne-Laure Bailly, Amandine Cartier-Michaud, Annie Boned, Marc Dalod, Estelle Duprez, Paul Genever, Mark Coles, Marc Bajenoff, Luc Xerri, Michel Aurrand-Lions, Claudine Schiff, Stéphane J.C. Mancini
Publikováno v:
Cell Reports, Vol 26, Iss 12, Pp 3257-3271.e8 (2019)
Summary: In the bone marrow, CXCL12 and IL-7 are essential for B cell differentiation, whereas hematopoietic stem cell (HSC) maintenance requires SCF and CXCL12. Peri-sinusoidal stromal (PSS) cells are the main source of IL-7, but their characterizat
Externí odkaz:
https://doaj.org/article/ca400878cbd04e4eb0894bcc243a5168
Autor:
Johnny Bonnardel, Clément Da Silva, Sandrine Henri, Samira Tamoutounour, Lionel Chasson, Frederic Montañana-Sanchis, Jean-Pierre Gorvel, Hugues Lelouard
Publikováno v:
Cell Reports, Vol 11, Iss 5, Pp 770-784 (2015)
Peyer’s patches (PPs) are primary inductive sites of mucosal immunity. Defining PP mononuclear phagocyte system (MPS) is thus crucial to understand the initiation of mucosal immune response. We provide a comprehensive analysis of the phenotype, dis
Externí odkaz:
https://doaj.org/article/fd2f4a4d04694ae3a6b7b3bd9c0b015f
Autor:
Jessica Perego, Clarisse Bourbon, Lionel Chasson, Caroline Laprie, Lionel Spinelli, Voahirana Camosseto, Evelina Gatti, Philippe Pierre
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Multi-organ failure in response to uncontrolled microbial infection is characterized by low blood pressure accompanied by a systemic over-inflammation state, caused by massive pro-inflammatory cytokines release and liver damage. Recently, the integra
Externí odkaz:
https://doaj.org/article/99f0ad648c9a4a20869775ca96b5d60e