Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Lionel Bosquée"'
Autor:
Jacques De Grève, Jan Van Meerbeeck, Johan F Vansteenkiste, Lore Decoster, Anne-Pascale Meert, Peter Vuylsteke, Christian Focan, Jean-Luc Canon, Yves Humblet, Guy Berchem, Benoit Colinet, Danny Galdermans, Lionel Bosquée, Joanna Vermeij, Alex Dewaele, Caroline Geers, Denis Schallier, Erik Teugels
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0147599 (2016)
INTRODUCTION:Epidermal Growth Factor Receptor (EGFR) tyrosine kinase inhibition is the preferred first-line treatment of advanced adenocarcinoma of the lung that harbors EGFR activating tyrosine kinase domain mutations. Most data available pertain to
Externí odkaz:
https://doaj.org/article/d77d90c2874a41ca9219fe0d09d1012a
Autor:
Silvia Novello, Giorgio V. Scagliotti, Shande Tang, Amelie Forest, Edurne Arriola, Karl-Matthias Deppermann, Tuan S. Nguyen, Martin Reck, Lionel Bosquée, Siva Rama Prasad Kambhampati, Gilberto de Castro, Ruslan D. Novosiadly, Murat Kiyik, Jan Cosaert, Ruben Dario Kowalyszyn
INTRODUCTION: Type 1 insulin-like growth factor receptor is deregulated in solid tumors. Cixutumumab, a monoclonal antibody that inhibits the activity of type 1 insulin-like growth factor receptor, was investigated in combination with pemetrexed/cisp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b73392044423f695a129a3149bd25d30
http://hdl.handle.net/2318/1588421
http://hdl.handle.net/2318/1588421
Autor:
Martin Reck, Elaine M. Paul, Pilar Lianes-Barragán, Christos Chouaid, Entisar Sigal, Joachim von Pawel, T. LeChevalier, Giorgio V. Scagliotti, Anders Mellemgaard, Benjamin Besse, Lionel Bosquée, Rodrigo Ruiz-Soto, Enriqueta Felip, Lone Ottesen
Publikováno v:
Journal of Thoracic Oncology. 8:1529-1537
Introduction: This randomized open-label phase II study evaluated the efficacy, safety, and tolerability of pazopanib in combination with pemetrexed compared with the standard cisplatin/pemetrexed doublet in patients with previously untreated, advanc
Autor:
Jean-Luc Canon, Guy Berchem, Christian Focan, Joanna Vermeij, D. Galdermans, Jacques De Greve, Benoit Colinet, Lionel Bosquée, Yves Humblet, Lore Decoster, Erik Teugels, Alex Dewaele, Denis Schallier, Anne-Pascale Meert, Jan P. van Meerbeeck, Peter Vuylsteke, Caroline Geers, Johan Vansteenkiste
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0147599 (2016)
PLoS ONE
PloS one, 11 (3
PLOS ONE
PLoS ONE
PloS one, 11 (3
PLOS ONE
INTRODUCTION: Epidermal Growth Factor Receptor (EGFR) tyrosine kinase inhibition is the preferred first-line treatment of advanced adenocarcinoma of the lung that harbors EGFR activating tyrosine kinase domain mutations. Most data available pertain t
Autor:
Paul Germonpré, Robert Gosselin, Lionel Bosquée, Yoshiro Kishi, Jan P. van Meerbeeck, Paul De Vuyst, Kristiaan Nackaerts, Eliane Kellen, Walter De Wever, Joris R. Delanghe, Kevin Hollevoet, Catherine Legrand
Publikováno v:
Journal of thoracic oncology
Introduction: Soluble mesothelin (SM), megakaryocyte potentiating factor (MPF), and osteopontin (OPN) are blood biomarkers of mesothelioma. This study evaluates their use as markers of response to therapy and outcome. Methods: Sixty-two patients with
Autor:
Krzystof Konopa, Sabine Margerit, Jan P. van Meerbeeck, Frederique Bustin, Lionel Bosquée, Paul Baas, Ernest Marshall, Baktiar Hasan, Christian Fink, Anne-Marie C. Dingemans, Paul Lorigan, Mary O'Brien, Jos A. Stigt
Publikováno v:
European Journal of Cancer, 47(15), 2322-2330. ELSEVIER SCI LTD
Purpose The EORTC 08062 phase II randomised trial investigated the activity and safety of single agent amrubicin, cisplatin combined with amrubicin, and cisplatin combined with etoposide as first line treatment in extensive disease (ED) small cell lu
Autor:
Stéphane Holbrechts, Lionel Duck, Jean-Luc Canon, Lionel Bosquée, Jean Francois Baurain, Kristin Jochmans, Ismail Elalamy, Alain Bols, Michel Peeters, Jeroen Mebis, Willem Lybaert, Joëlle Nortier, Paul Clement, Ahmad Awada
Publikováno v:
Journal of blood disorders & transfusion, 5 (4
Venous Thromboembolism (VTE) is a frequent cause of mortality and morbidity in patients with malignancy. Thrombosis is one of the leading causes of death in patients with malignancy after cancer itself. As such, prompt recognition and treatment of VT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79f9de0ec4793ba5be68b7dd3c96eb01
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/199342
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/199342
Autor:
Frances A. Shepherd, Philip Clingan, Mark A. Socinski, Markus F. Renschler, Martin Steins, Jose Manuel Trigo, J. Mezger, Jeffrey A. Bubis, R. McNally, E. H. Paschold, Lionel Bosquée, Martin Reck, J. von Pawel, Spigel, Wolfgang Schuette, Kristiaan Nackaerts, Robert M. Jotte, Paul Lorigan, M. O'Brien, Manuel Domine
Publikováno v:
ResearcherID
Aims: Amrubicin, a 3rd gen. anthracycline and potent topoisomerase II inhibitor, has shown activity in SCLC. ACT-1 compared the safety and efficacy of amr vs. topo for 2nd line treatment of SCLC. Methods: 637 pts were random. 2:1 amr 40mg/m2 IV d 1
Autor:
Lionel Bosquée, Eliane Kellen, Yoshiro Kishi, Jan P. van Meerbeeck, Paul Germonpré, Kristiaan Nackaerts, Joris R. Delanghe, Kevin Hollevoet, Paul De Vuyst, Olivier Thas, Catherine Legrand, J. Thimpont
Publikováno v:
Chest, Vol. 141, no. 2, p. 477-484 (2012)
Chest
Chest
Background: Soluble mesothelin (SM) and megakaryocyte potentiating factor (MPF) are serum biomarkers of mesothelioma. This study examined the effect of clinical covariates on biomarkers levels and their diagnostic and prognostic value. Methods: Five
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b3b4e56696f524df8f11184e4634fd6
https://hdl.handle.net/2078.1/127126
https://hdl.handle.net/2078.1/127126
Autor:
Eliane Kellen, Joris R. Delanghe, Jan P. van Meerbeeck, Catherine Legrand, Paul Germonpré, Yoshiro Kishi, Lionel Bosquée, J. Thimpont, Kevin Hollevoet, Paul De Vuyst, Kristiaan Nackaerts
Publikováno v:
American journal of respiratory and critical care medicine
Rationale: Soluble mesothelin (SM) is currently the reference serum biomarker of malignant pleural mesothelioma (MPM). Megakaryocyte potentiating factor (MPF), which originates from the same precursor protein, is potentially more sensitive, yet lacks