Impact of the evolution in RAS mutation analysis in Australian patients with metastatic colorectal cancer

Autor: Chia Yuen Chong, Azim Jalali, Hui Li Wong, Matthew Loft, Rachel Wong, Margaret Lee, Lucy Gately, Wei Hong, Jeremy Shapiro, Suzanne Kosmider, Jeannie Tie, Sumitra Ananda, Justin M Yeung, Brigette Ma, Matthew Burge, Ross Jennens, Ben Tran, Belinda Lee, Lionel Lim, Andrew Dean, Louise Nott, Peter Gibbs

Publikováno v: Asia-Pacific journal of clinical oncologyREFERENCES. 18(5)

RAS mutation testing now routinely informs the optimal management of metastatic colorectal cancer (mCRC), specifically the finding of a RAS mutation defines patients who will not benefit from treatment with an epidermal growth factor receptor inhibit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3827767554a9ee56262c83f14f7ca53
https://pubmed.ncbi.nlm.nih.gov/35073441

The impact of bevacizumab in metastatic colorectal cancer with an intact primary tumor: Results from a large prospective cohort study

Autor: Jeanne Tie, Jeremy Shapiro, Desmond Yip, Lionel Lim, Ben Tran, Sumitra Ananda, Greg Stefanou, Matthew Burge, Louise M. Nott, Peter Gibbs, Mark Tacey, Phillip Parente, Rachel Wong, Hui-Li Wong, Belinda Lee, Gary Richardson, Margaret Lee, Mahesh Iddawela, Jeremy David Power, Ross Jennens, Natalie Turner

Publikováno v: Asia-Pacific Journal of Clinical Oncology. 13:314-321

Background Debate continues regarding the benefits versus risks of initial resection of the primary tumor in metastatic colorectal cancer (mCRC) patients with an asymptomatic primary tumor. Although the benefit of the anti-vascular endothelial growth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ba1e8692a556e65e1b87dff0851eb736
https://doi.org/10.1111/ajco.12639

Effect of primary tumor side on survival outcomes in untreated patients with metastatic colorectal cancer when selective internal radiation therapy is added to chemotherapy : combined analysis of two randomized controlled studies

Autor: Peter Gibbs, Volker Heinemann, Navesh K. Sharma, Julien Taieb, Jens Ricke, Marc Peeters, Michael Findlay, Bridget Robinson, Christopher Jackson, Andrew Strickland, Val Gebski, Mark Van Buskirk, Huaqing Zhao, Guy van Hazel, Michael Brown, Matthew Burge, Giuseppe Cardaci, Stephen Clarke, Paul Eliadis, Tom Ferguson, Vinod Ganju, Philip James, Chris Karapetis, Winston Liauw, Gavin Marx, Marco Matos, Louise Nott, Nick Pavlakis, Alex Powell, Timothy Price, David Ransom, Eva Segelov, Jenny Shannon, Nimit Singhal, Euan Walpole, Michel Craninx, Thierry Delaunoit, Amélie Deleporte, Michel Ferrante, Karen Geboes, Alain Hendlisz, Koen Hendrickx, Marc De Man, Els Monsaert, Veerle Moons, Marc Polus, Eveline Boucher, Jacques Balosso, Patrick Chevallier, Samy Louafi, Marc Pracht, Christine Rebischung, Denis Smith, Eric Terrebonne, Harald-Robert Bruch, Gerald Gehbauer, Thomas Helmberger, Yon-Dschun Ko, Hendrik Kröning, Frank Lammert, Arnd Nusch, Stefan Pluntke, Karsten Ridwelski, Jorge Riera-Knorrenschild, Hanno Riess, Jorge Ramon Riera, Tilmann Sauerbruch, Klemens Scheidhauer, Oliver Stötzer, Klaus Tatsch, Ursula Vehling-Kaiser, Thomas Vogl, Alex Beny, Ravit Geva, Einat Shacham-Shmueli, Salomon Stemmer, Thomas Tichler, Ido Wolf, Bruna Angelelli, Andrea Martoni, Michael P.N. Findlay, Richard Isaacs, Anne O’Donnell, David Perez, Bridget A. Robinson, Javier Rodríguez, Ruth Vera-Garcia, Pradip Amin, Daniel Bloomgarden, James Bui, James Carlisle, Seungjean Chai, Yi-Jen Chen, Michael Chuong, Andrew Coveler, Francis Facchini, Gary Frenette, Jacob Frick, Michael Garofalo, Benjamin George, Michael Gordon, Seza Gulec, James Hannigan, Matthew Holtzman, Andreas Kaubisch, Adeel Kaiser, Todd Kooy, Steven Limentani, Jeffrey Margolis, Robert Martin, Howard Ozer, Siddarth Padia, William Rilling, Michael Savin, Elyse Schneiderman, Grant Seeger, Navesh Sharma, Stephen Shibata, Randall Smith, Eric Wang, Samuel Whiting, Morteza Aghmesheh, Mathew Burge, Prasad Cooray, Kynan Feeney, Lionel Lim, Madhu Singh, Craig Underhill, Amelie Deleporte, Aurelie Durand, Sandrine Faivre, Aurelie Ferru, Pascal Hammel, Christoph Bremer, Maike De Wit, Hubert Ayala, Norman Heching, Adi Shani, Cristina Granetto, Gianluca Masi, Stefania Mosconi, Gianmauro Numico, Antonio Trogu, Yeul Hong Kim, Han Sae-Won, Chris Jackson, Anne O'Donnell, Maria Fragoso, Iain Tan, Ana Ruiz Casado, Jin Tung Liang, Jin Hwang Liu, Steven Ades, Miklos Auber, Patrick Boland, Charles Bowers, Martin Crain, Kyran Dowling, Renuka Iyer, Lynn Ratner, Federico Sanchez, Patricia Stoltzfus, Mark Westcott

Publikováno v: Clinical colorectal cancer

The primary tumor side is emerging as a prognostic factor for patients with liver metastatic colorectal cancer (mCRC). In a combined analysis of data from 2 randomized studies, the addition of selective internal radiation therapy to first-line chemot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::571cccccf3d6dee219ad94de3bda37e6
https://hdl.handle.net/10067/1553790151162165141

Clinical insights for hematological malignancies from an artificial intelligence decision-support tool

Autor: Miyoung Kim, Winnie Felix, Jane L. Snowdon, Hyo Jung Kim, Lionel Lim, S Dilhan Weeraratne, Dae Young Zang, Young Kyung Lee, Eunyup Lee, Kibum Jeon, Irene Dankwa-Mullan, Ho Young Kim, Boram Han, Jee Soo Lee

Publikováno v: Journal of Clinical Oncology. 37:e13023-e13023

e13023 Background: Next generation sequencing (NGS) in hematological tumors is increasingly shaping clinical treatment decisions at the point of care. While the impact of NGS panels in solid tumors is largely therapeutic, targeted sequencing in hemat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0761640e2d19069650936acac992aaa3
https://doi.org/10.1200/jco.2019.37.15_suppl.e13023

MicroRNA‐494 within an oncogenic microRNA megacluster regulates G 1 /S transition in liver tumorigenesis through suppression of mutated in colorectal cancer

Autor: Brittany Anderton, Andrei Goga, Adam J. Dupuy, Jesse D. Riordan, Asha Balakrishnan, Kirk D. Jones, Mona Jodari, Holger Willenbring, David Brown, Raymond Ng, Guisheng Song, Lionel Lim, Aaron N. Chang, Xin Chen, Siu Tim Cheung, Noelle E. Huskey

Publikováno v: Hepatology (Baltimore, Md.)

Hepatocellular carcinoma (HCC) is associated with poor survival for patients and few effective treatment options, raising the need for novel therapeutic strategies. MicroRNAs (miRNAs) play important roles in tumor development and show deregulated pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc9051f879ab32b14dc3db3b54e33ab
https://doi.org/10.1002/hep.26662