Characterization of a Clinically and Biologically Defined Subgroup of Patients with Autism Spectrum Disorder and Identification of a Tailored Combination Treatment.

Autor: Pérez-Cano L; Discovery and Data Science (DDS) Unit, STALICLA SL, Moll de Barcelona, s/n, Edif Este, 08039 Barcelona, Spain., Boccuto L; JC Self Research Institute, Greenwood Genetic Center, Greenwood, SC 29649, USA.; Healthcare Genetics and Genomics, School of Nursing, Clemson University, Clemson, SC 29634, USA., Sirci F; Discovery and Data Science (DDS) Unit, STALICLA SL, Moll de Barcelona, s/n, Edif Este, 08039 Barcelona, Spain., Hidalgo JM; Discovery and Data Science (DDS) Unit, STALICLA SL, Moll de Barcelona, s/n, Edif Este, 08039 Barcelona, Spain., Valentini S; Discovery and Data Science (DDS) Unit, STALICLA SL, Moll de Barcelona, s/n, Edif Este, 08039 Barcelona, Spain., Bosio M; Discovery and Data Science (DDS) Unit, STALICLA SL, Moll de Barcelona, s/n, Edif Este, 08039 Barcelona, Spain., Liogier D'Ardhuy X; Drug Development Unit (DDU), STALICLA SA, Avenue de Sécheron 15, 1202 Geneva, Switzerland., Skinner C; JC Self Research Institute, Greenwood Genetic Center, Greenwood, SC 29649, USA., Cascio L; JC Self Research Institute, Greenwood Genetic Center, Greenwood, SC 29649, USA.; Research and Education in Disease Diagnosis and Interventions (REDDI) Lab, Center for Innovative Medical Devices and Sensors (CIMeDS), Clemson University, Clemson, SC 29634, USA., Srikanth S; JC Self Research Institute, Greenwood Genetic Center, Greenwood, SC 29649, USA.; Research and Education in Disease Diagnosis and Interventions (REDDI) Lab, Center for Innovative Medical Devices and Sensors (CIMeDS), Clemson University, Clemson, SC 29634, USA., Jones K; JC Self Research Institute, Greenwood Genetic Center, Greenwood, SC 29649, USA.; Research and Education in Disease Diagnosis and Interventions (REDDI) Lab, Center for Innovative Medical Devices and Sensors (CIMeDS), Clemson University, Clemson, SC 29634, USA., Buchanan CB; JC Self Research Institute, Greenwood Genetic Center, Greenwood, SC 29649, USA., Skinner SA; JC Self Research Institute, Greenwood Genetic Center, Greenwood, SC 29649, USA., Gomez-Mancilla B; Drug Development Unit (DDU), STALICLA SA, Avenue de Sécheron 15, 1202 Geneva, Switzerland.; Department of Neurology and Neurosurgery, McGill University, Montreal, QC H3A 0G4, Canada., Hyvelin JM; Drug Development Unit (DDU), STALICLA SA, Avenue de Sécheron 15, 1202 Geneva, Switzerland., Guney E; Discovery and Data Science (DDS) Unit, STALICLA SL, Moll de Barcelona, s/n, Edif Este, 08039 Barcelona, Spain., Durham L; Discovery and Data Science (DDS) Unit, STALICLA SL, Moll de Barcelona, s/n, Edif Este, 08039 Barcelona, Spain.; Drug Development Unit (DDU), STALICLA SA, Avenue de Sécheron 15, 1202 Geneva, Switzerland.

Publikováno v: Biomedicines [Biomedicines] 2024 Apr 30; Vol. 12 (5). Date of Electronic Publication: 2024 Apr 30.

Adaptive behavior in autism:Minimal clinically important differences on the Vineland-II

Autor: Chatham, C. H., Taylor, K. I., Charman, T., Liogier D'ardhuy, X., Eule, E., Fedele, A., Hardan, A. Y., Loth, E., Murtagh, L., del Valle Rubido, M., San Jose Caceres, A., Sevigny, J., Sikich, L., Snyder, L., Tillmann, J. E., Ventola, P. E., Walton-Bowen, K. L., Wang, P. P., Willgoss, T., Bolognani, F.

Publikováno v: Chatham, C H, Taylor, K I, Charman, T, Liogier D'ardhuy, X, Eule, E, Fedele, A, Hardan, A Y, Loth, E, Murtagh, L, del Valle Rubido, M, San Jose Caceres, A, Sevigny, J, Sikich, L, Snyder, L, Tillmann, J E, Ventola, P E, Walton-Bowen, K L, Wang, P P, Willgoss, T & Bolognani, F 2017, ' Adaptive behavior in autism : Minimal clinically important differences on the Vineland-II ', Autism research . https://doi.org/10.1002/aur.1874

Autism Spectrum Disorder (ASD) is associated with persistent impairments in adaptive abilities across multiple domains. These social, personal, and communicative impairments become increasingly pronounced with development, and are present regardless

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2761::f8d5bf02e4f5e0a1064fbeaf7dee6522
https://kclpure.kcl.ac.uk/en/publications/8900fd8f-6b65-4156-b167-44388bf3519f

Adaptive behavior in adolescents and adults with Down syndrome: Results from a 6-month longitudinal study.

Autor: Spiridigliozzi GA; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina., Goeldner C; F. Hoffmann-La Roche, Roche Pharma Research and Early Development, Neuroscience, Roche Innovation Center Basel, Basel, Switzerland., Edgin J; Department of Psychology, University of Arizona, Tucson, Arizona., Hart SJ; Department of Pediatrics, Duke University Medical Center, Durham, North Carolina., Noeldeke J; F. Hoffmann-La Roche, Roche Pharma Research and Early Development, Neuroscience, Roche Innovation Center Basel, Basel, Switzerland., Squassante L; F. Hoffmann-La Roche, Roche Pharma Research and Early Development, Neuroscience, Roche Innovation Center Basel, Basel, Switzerland., Visootsak J; F. Hoffmann-La Roche, Roche Pharma Research and Early Development, Neuroscience, Roche Innovation Center, New York, New York., Heller JH, Khwaja O; F. Hoffmann-La Roche, Roche Pharma Research and Early Development, Neuroscience, Roche Innovation Center Basel, Basel, Switzerland., Kishnani PS; Department of Pediatrics, Duke University Medical Center, Durham, North Carolina., Liogier d'Ardhuy X; F. Hoffmann-La Roche, Roche Pharma Research and Early Development, Neuroscience, Roche Innovation Center Basel, Basel, Switzerland.

Publikováno v: American journal of medical genetics. Part A [Am J Med Genet A] 2019 Jan; Vol. 179 (1), pp. 85-93. Date of Electronic Publication: 2018 Dec 20.

Family-Centric Applied Behavior Analysis Facilitates Improved Treatment Utilization and Outcomes.

Autor: Adelson, Robert P.¹ (AUTHOR) robert.adelson@fortahealth.com, Ciobanu, Madalina¹ (AUTHOR) mciobanu@fortahealth.com, Garikipati, Anurag¹ (AUTHOR) agarikipati@fortahealth.com, Castell, Natalie J.¹ (AUTHOR) natalie.castell@fortahealth.com, Singh, Navan Preet¹ (AUTHOR) nsingh@fortahealth.com, Barnes, Gina¹ (AUTHOR) gbarnes@fortahealth.com, Rumph, Jodi Kim¹ (AUTHOR) anshu@fortahealth.com, Mao, Qingqing¹ (AUTHOR) qmao@fortahealth.com, Roane, Henry S.² (AUTHOR) roaneh@upstate.edu, Vaish, Anshu¹ (AUTHOR), Das, Ritankar¹ (AUTHOR)

Publikováno v: Journal of Clinical Medicine. Apr2024, Vol. 13 Issue 8, p2409. 17p.

Pharmacological interventions to improve cognition and adaptive functioning in Down syndrome: Strides to date.

Autor: Hart SJ; Department of Pediatrics, Duke University Medical Center, Durham, North Carolina., Visootsak J; F. Hoffmann-La Roche, Roche Pharma Research and Early Development, Neuroscience, Roche Innovation Center New York, New York, New York., Tamburri P; F. Hoffmann-La Roche, Roche Pharma Research and Early Development, Neuroscience, Roche Innovation Center New York, New York, New York., Phuong P; F. Hoffmann-La Roche, Roche Pharma Research and Early Development, Neuroscience, Roche Innovation Center New York, New York, New York., Baumer N; Department of Neurology, Boston Children's Hospital, Boston, Massachusetts.; Down Syndrome Program, Developmental Medicine Center, Boston Children's Hospital, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts., Hernandez MC; F. Hoffmann-La Roche, Roche Pharma Research and Early Development, Neuroscience, Roche Innovation Center Basel, Basel, Switzerland., Skotko BG; Harvard Medical School, Boston, Massachusetts.; Down Syndrome Program, Division of Medical Genetics, Department of Pediatrics, Massachusetts General Hospital, Boston, Massachusetts., Ochoa-Lubinoff C; Section of Developmental-Behavioral Pediatrics, Department of Pediatrics, Rush University Medical Center, Chicago, Illinois., Liogier D'Ardhuy X; F. Hoffmann-La Roche, Roche Pharma Research and Early Development, Neuroscience, Roche Innovation Center Basel, Basel, Switzerland., Kishnani PS; Department of Pediatrics, Duke University Medical Center, Durham, North Carolina., Spiridigliozzi GA; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina.

Publikováno v: American journal of medical genetics. Part A [Am J Med Genet A] 2017 Nov; Vol. 173 (11), pp. 3029-3041. Date of Electronic Publication: 2017 Sep 08.