Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Linyu Han"'
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-15 (2023)
Abstract Background Gastric cancer remains the leading cause of cancer death in the world. It is increasingly evident that long non-coding RNAs (lncRNAs) transcribed from the genome-wide association studies (GWAS)-identified gastric cancer risk loci
Externí odkaz:
https://doaj.org/article/9ca1394df16a4ea78a83be5f46e77122
Autor:
Nasha Zhang, Xijun Liu, Linying Huang, Jiajia Zeng, Chi Ma, Linyu Han, Wenwen Li, Jinming Yu, Ming Yang
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113479- (2023)
Summary: Alternative polyadenylation (APA) plays a major role in controlling transcriptome diversity and therapeutic resistance of cancers. However, long non-coding RNAs (lncRNAs) involved in pathological APA remain poorly defined. Here, we functiona
Externí odkaz:
https://doaj.org/article/4e6ed6ece9604fffa065c16b8fe2ab8b
Autor:
Ling Wei, Jujie Sun, Xingwu Wang, Yizhou Huang, Linying Huang, Linyu Han, Yanxiu Zheng, Yuan Xu, Nasha Zhang, Ming Yang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Pancreatic cancer is the eighth leading cause of cancer-related deaths worldwide. Chemotherapy including gemcitabine, 5-fluorouracil, adriamycin and cisplatin, immunotherapy with immune checkpoint inhibitors and targeted therapy have been demonstrate
Externí odkaz:
https://doaj.org/article/02773570de1441668df1317b129fb2ff
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
N6-Methyladenosine (m6A) methylation is one of the most extremely examined RNA modifications. M6A modification evidently impacts cancer development by effecting RNA metabolism. Long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) are involved in mul
Externí odkaz:
https://doaj.org/article/f497795aa301403d9e7b47c30e5fa68b
Autor:
Xiaolu Wei, Nan Si, Yuefei Zhang, Haiyu Zhao, Jian Yang, Hongjie Wang, Lianmei Wang, Linyu Han, Baolin Bian
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169141 (2017)
Cinobufacin injection, also known as huachansu, is a preparation form of Cinobufacini made from Cinobufacin extract liquid. Despite that Cinobufacin injection is shown to shrink liver and gastric tumors, improving patient survival and life quality, t
Externí odkaz:
https://doaj.org/article/7ebeeee23aa842d69c73126ce77b36d9
Circular RNAs (circRNA) are a group of noncoding, covalently uninterrupted loop transcripts, most of which remain to be functionally characterized. Here, we identified circPDIA4 as an oncogenic circRNA in gastric cancer. Clinically, circPDIA4 was sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025b6512e460095688079c3d686f1719
https://doi.org/10.1158/0008-5472.c.6514413.v1
https://doi.org/10.1158/0008-5472.c.6514413.v1
Table S1 shows primers for RT-qPCR. Table S2 shows sequences of shRNAs and siRNAs. Table S3 shows antibodies used in the study. Table S4 shows the sequence of the biotin-labeled probes for circPDIA4 and controls. Table S5 shows the overlap circRNAs o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cde1d54aba3590cacc647767dc94cb4
https://doi.org/10.1158/0008-5472.22433616
https://doi.org/10.1158/0008-5472.22433616
Figure S1 shows elevated expression of circPDIA4 in gastric cancer tissues and impacts on viability of gastric cancer cells. Figure S2 shows that circPDIA4 enhanced invasive activities of gastric cancer cells. Figure S3 shows that circPDIA4 enhanced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::608e8b9f1e44e24d062c33736088b21f
https://doi.org/10.1158/0008-5472.22433619
https://doi.org/10.1158/0008-5472.22433619
Autor:
Jiajia Zeng, Linyu Han, Teng Wang, Linying Huang, Yanxiu Zheng, Nasha Zhang, Ziqiang Li, Ming Yang
Publikováno v:
Pharmacogenomics and Personalized Medicine.
Jiajia Zeng,1,* Linyu Han,1,* Teng Wang,1,* Linying Huang,1 Yanxiu Zheng,1 Nasha Zhang,2 Ziqiang Li,3 Ming Yang1 1Shandong Provincial Key Laboratory of Radiation Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Sh
Publikováno v:
Cancer research.
Circular RNAs (circRNA) are a group of noncoding, covalently uninterrupted loop transcripts, most of which remain to be functionally characterized. Here, we identified circPDIA4 as an oncogenic circRNA in gastric cancer. Clinically, circPDIA4 was sig