Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Linus Chang"'
Publikováno v:
Journal of Minimally Invasive Gynecology. 19:172-175
The role of lymphadenectomy in the management of endometrial carcinoma remains controversial in gynecologic oncology. Comprehensive pelvic and paraaortic lymphadenectomy should be performed in patients with intermediate- and high-risk endometrial can
Autor:
Tanya Crockford, D. Zernich, Lauren Kate Ely, Rhonda Holdsworth, Andrew G. Brooks, Jamie Rossjohn, Brian D. Tait, Lars Kjer-Nielsen, W.A. Macdonald, Nihay Laham, Mandvi Bharadwaj, James McCluskey, Linus Chang, Chen Au Peh, Nicole A. Mifsud, Anthony W. Purcell, Travis Clarke Beddoe, Stephen P. Bottomley
Publikováno v:
The Journal of Experimental Medicine
HLA class I polymorphism creates diversity in epitope specificity and T cell repertoire. We show that HLA polymorphism also controls the choice of Ag presentation pathway. A single amino acid polymorphism that distinguishes HLA-B*4402 (Asp116) from B
Autor:
Travis Clarke Beddoe, Michelle A. Dunstone, Linus Chang, Jamie Rossjohn, Qiyuan Chen, Anthony W. Purcell, Lars Kjer-Nielsen, James McCluskey, Heather Jackson, Weisan Chen, Andrew I. Webb, Marie-Isabel Aguilar
Publikováno v:
Journal of Biological Chemistry. 279:23438-23446
NY-ESO-1, a commonly expressed tumor antigen of the cancer-testis family, is expressed by a wide range of tumors but not found in normal adult somatic tissue, making it an ideal cancer vaccine candidate. Peptides derived from NY-ESO-1 have shown prec
Publikováno v:
International Journal of Peptide Research and Therapeutics. 10:553-559
Autor:
S. Flynn, Linus Chang, Andrew G. Brooks, Lars Kjer-Nielsen, Anthony W. Purcell, Margo C. Honeyman, James McCluskey, Stuart I. Mannering, Leonard C. Harrison
Publikováno v:
Tissue Antigens. 62:408-417
We describe a strategy for identifying ligands of human leukocyte antigen (HLA) class I molecules based on a peptide library-mediated in vitro assembly of recombinant class I molecules. We established a microscale class I assembly assay and used a ca
Publikováno v:
Letters in Peptide Science. 10:553-559
Autor:
David M. Koelle, Lauren Kate Ely, Rhonda Holdsworth, Craig Steven Clements, James McCluskey, Andrew G. Brooks, Linus Chang, Scott R. Burrows, Louis Lu, Brian D. Tait, W.A. Macdonald, David S. Williams, George O. Lovrecz, Nicole A. Mifsud, Anthony W. Purcell, Lars Kjer-Nielsen, Jeffrey J. Gorman, Jamie Rossjohn
Publikováno v:
The Journal of Experimental Medicine
HLA-B*4402 and B*4403 are naturally occurring MHC class I alleles that are both found at a high frequency in all human populations, and yet they only differ by one residue on the α2 helix (B*4402 Asp156→B*4403 Leu156). CTLs discriminate between HL
Autor:
Porntip Prapunpoj, Samantha J. Richardson, Sharon L. A. Munro, Linus Chang, Angela R. Aldred, Gerhard Schreiber
Publikováno v:
Scopus-Elsevier
SUMMARY 1. Appropriate distribution of thyroxine between the lipid-soluble compartments of cells and tissues and the extracellular aqueous space is established by binding to extracellular proteins. Among these proteins, transthyretin is of particular
Autor:
Jeremy Cohen, Linus Chang, John Galligan, Bala Venkatesh, Graeme A. Macdonald, Aidan J. Woodward, Brett McWhinney, Terrence C. H. Tan
Publikováno v:
Journal of hepatology. 53(5)
Background & Aims Adrenal insufficiency (AI) has been reported in patients with advanced liver disease. Diagnosing AI is problematic owing to controversies in using total serum cortisol as a measure of adrenal function. No published data exist on dir
Publikováno v:
SNPD
Since 2005 the Taiwanese government has invested over $1.2 billion into the M-Taiwan program to bolster Taiwan’s broadband mobile communications industry and infrastructure. In addition to building a fiber backbone and providing RD (2) WiFi hot zon