Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Linu S. Abraham"'
Publikováno v:
PLoS Genetics, Vol 6, Iss 8 (2010)
The large conductance, voltage- and calcium-dependent potassium (BK) channel serves as a major negative feedback regulator of calcium-mediated physiological processes and has been implicated in muscle dysfunction and neurological disorders. In additi
Externí odkaz:
https://doaj.org/article/865d9f64d56e4a3ebcb58c42d636b931
Autor:
Courtney L. Kraus, Dru S. Dace, Nuran Ercal, Linu S. Abraham, Douglas Cox, Rajendra S. Apte, Abdoulaye Sene, A. M. Schimel
Publikováno v:
The American Journal of Pathology. 178:2032-2043
Oxidative stress plays a critical role in accelerating retinal pigment epithelial dysfunction and death in degenerative retinal diseases, including age-related macular degeneration. Given the key role of oxidative stress–induced retinal pigment epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4cfe9fb25bb99f81c5972a1613c98f0
https://doi.org/10.1016/j.ajpath.2011.01.036
https://doi.org/10.1016/j.ajpath.2011.01.036
Publikováno v:
Biomedical Chromatography. 23:119-123
A reverse-phase HPLC method incorporating dithiothreitol (DTT) reduction for quantitative determination of oxidized glutathione (GSSG) in biological samples is described here. This method is based on our previous enzymatic reduction technique that us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f20b9ee38b1c51b35259982a9cebb444
https://doi.org/10.1002/bmc.1083
https://doi.org/10.1002/bmc.1083
Publikováno v:
Free Radical Research. 42:372-377
The antioxidant potential of N-acetylcysteine amide (NACA), also known as AD4, was assessed by employing different in vitro assays. These included reducing power, free radical scavenging capacities, peroxidation inhibiting activity through linoleic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d869051e976b03c83ef27524fdd500b
https://doi.org/10.1080/10715760801998638
https://doi.org/10.1080/10715760801998638
Autor:
Hongkyun Kim, Christian Silvestri, Linu S. Abraham, Mark J. Alkema, Jacob D. Furst, Yung-Chi Huang, Kelly H. Oh, Chandler Gegg, Daniela Raicu
Publikováno v:
BMC Neuroscience
Background Large conductance, calcium-activated BK channels regulate many important physiological processes, including smooth muscle excitation, hormone release and synaptic transmission. The biological roles of these channels hinge on their unique a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9a0ad848018b1a7f46dabb01cbf375
http://europepmc.org/articles/PMC4411755
http://europepmc.org/articles/PMC4411755
Autor:
Linu S. Abraham, Frans van Roy, Kris Gevaert, Hyun J. Oh, Hongkyun Kim, Joseph X. DiMario, Joshua R. Sanes, Christophe P. Stove, Tomasz J. Proszynski, Jolanda van Hengel
Publikováno v:
The Journal of biological chemistry. 287(26)
The dystrophin complex is a multimolecular membrane-associated protein complex whose defects underlie many forms of muscular dystrophy. The dystrophin complex is postulated to function as a structural element that stabilizes the cell membrane by link
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec05af78d3a7d377a67f96f0e356a083
https://pubmed.ncbi.nlm.nih.gov/22577143
https://pubmed.ncbi.nlm.nih.gov/22577143
Autor:
Linu S. Abraham, Michael W. Lieberman, Björn Rozell, Abdelaziz Elgadi, Katarina Carlsson, Agne Larsson, Nuran Ercal, Zheng Zheng Shi, Andreas Winkler, Svante Norgren, Runa Njålsson
Publikováno v:
Biochemical and biophysical research communications. 412(1)
Glutathione (GSH) is present in all mammalian tissues and plays a crucial role in many cellular processes. The second and final step in the synthesis involves the formation of GSH from gamma-glutamylcysteine (γ-GC) and glycine and is catalyzed by gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94eb181b5b723ba7306364f0f04f245e
https://pubmed.ncbi.nlm.nih.gov/21802407
https://pubmed.ncbi.nlm.nih.gov/21802407
Publikováno v:
Humanexperimental toxicology. 30(10)
The current study examined the impact of sub-chronic lead (Pb)-exposure upon global protein profile in rodent kidney (blood Pb levels ~50 μg/dL; 5 weeks oral Pb-acetate exposure). Utilizing 2D SDS-PAGE for kidney protein separation, greater than 500
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cd7b7e9c715d45f72b5f68b2406ce6d
https://pubmed.ncbi.nlm.nih.gov/21247988
https://pubmed.ncbi.nlm.nih.gov/21247988
Publikováno v:
Life sciences. 82(21-22)
Ionizing radiation is known to cause tissue damage in biological systems, mainly due to its ability to produce reactive oxygen species (ROS) in cells. Many thiol antioxidants have been used previously as radioprotectors, but their application has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df53c08d01cfde780741df586434ed70
https://pubmed.ncbi.nlm.nih.gov/18448127
https://pubmed.ncbi.nlm.nih.gov/18448127