Transcription factor 7 like 2 promotes metastasis in hepatocellular carcinoma via NEDD9-mediated activation of AKT/mTOR signaling pathway

Autor: Linsong Tang, Shengjun Xu, Rongli Wei, Guanghan Fan, Junbin Zhou, Xuyong Wei, Xiao Xu

Publikováno v: Molecular Medicine, Vol 30, Iss 1, Pp 1-13 (2024)

Abstract Background Hepatocellular carcinoma (HCC) is one of the most common malignant tumors of the digestive system, and the exact mechanism of HCC is still unclear. Transcription factor 7 like 2 (TCF7L2) plays a pivotal role in cell proliferation

Externí odkaz: https://doaj.org/article/530da51c71024243a030c0b36983fabe

Regulation of macrophage polarization and pyroptosis by 4-methylcatechol alleviates collagen-induced arthritis via Nrf2/HO-1 and NF-κB/NLRP3 signaling pathways.

Autor: Zhendong Y; Department of Orthopaedics Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University of Traditional Chinese Medicine, Jinan 250012, PR China. Electronic address: 19819092872@163.com., Changjun C; Department of Orthopaedic Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan 250012, PR China. Electronic address: Chenchangjun888@qq.com., Haocheng H; The First Clinical College, Shandong University, Jinan 250014, PR China. Electronic address: 15726066199@163.com., Qibin L; Department of Orthopaedic Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan 250012, PR China. Electronic address: lqb19971205@163.com., Dailing C; Department of Orthopaedics Surgery, Shandong Provincial Qianfoshan Hospital, Shandong Second Medical University, Jinan 250012, PR China. Electronic address: cdl202315069743385@163.com., Linsong T; Department of Orthopaedics Surgery, Shandong Provincial Qianfoshan Hospital, Shandong University of Traditional Chinese Medicine, Jinan 250012, PR China. Electronic address: 18353611168@163.com., Xuecheng S; Department of Orthopedic Trauma, Weifang People's Hospital, Weifang, Shandong, PR China. Electronic address: wfsunxuecheng@126.com., Gong M; Department of General Surgery, The First People's Hospital of Hangzhou Lin'an District (Hangzhou Medical College Affiliated Lin'an People's Hospital), Hangzhou 311300, PR China. Electronic address: gongmouchun@163.com., Lei Z; Department of Orthopaedic Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan 250012, PR China. Electronic address: qygkzl1818@163.com.

Publikováno v: International immunopharmacology [Int Immunopharmacol] 2024 Dec 21; Vol. 146, pp. 113855. Date of Electronic Publication: 2024 Dec 21.