Integrated Exposure-Response of Dupilumab in Children, Adolescents, and Adults With Atopic Dermatitis Using Categorical and Continuous Efficacy Assessments: A Population Analysis.

Autor: Briggs E; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, MI, USA.; A2-Ai, Ann Arbor, MI, USA., Kamal MA; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA. Mohamed.kamal@regeneron.com., Kosloski MP; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Linsmeier I; Arcus Biosciences, Hayward, CA, USA., Jusko N; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, MI, USA.; Amador Bioscience, Ann Arbor, MI, USA., Dolphin N; Amador Bioscience, Ann Arbor, MI, USA., Chittenden J; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Simpson EL; Oregon Health and Science University, Portland, OR, USA., Paller AS; Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Ann and Robert H. Lurie Children's Hospital, Chicago, IL, USA., Siegfried EC; Saint Louis University, St. Louis, MO, USA.; Cardinal Glennon Children's Hospital, St. Louis, MO, USA., Shumel B; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Levit NA; Dermatology Physicians of Connecticut, Fairfield, CT, USA., Bansal A; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Davis JD; Regeneron Pharmaceuticals Inc, Tarrytown, NY, USA., Chapel S; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, MI, USA.; Cardinal Glennon Children's Hospital, St. Louis, MO, USA., Smith DE; Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, MI, USA., Huniti N; Amador Bioscience, Ann Arbor, MI, USA.

Publikováno v: Pharmaceutical research [Pharm Res] 2023 Nov; Vol. 40 (11), pp. 2653-2666. Date of Electronic Publication: 2023 Dec 11.

Entropy production rate is maximized in non-contractile actomyosin.

Autor: Seara DS; Department of Physics, Yale University, 217 Prospect Street, New Haven, CT, 06511, USA.; Systems Biology Institute, Yale University, 850 West Campus Drive, West Haven, CT, 06516, USA., Yadav V; Systems Biology Institute, Yale University, 850 West Campus Drive, West Haven, CT, 06516, USA.; Department of Biomedical Engineering, Yale University, 55 Prospect Street, New Haven, CT, 06511, USA., Linsmeier I; Systems Biology Institute, Yale University, 850 West Campus Drive, West Haven, CT, 06516, USA.; Department of Biomedical Engineering, Yale University, 55 Prospect Street, New Haven, CT, 06511, USA., Tabatabai AP; Systems Biology Institute, Yale University, 850 West Campus Drive, West Haven, CT, 06516, USA.; Department of Biomedical Engineering, Yale University, 55 Prospect Street, New Haven, CT, 06511, USA., Oakes PW; Department of Physics & Astronomy, and Department of Biology, University of Rochester, Rochester, NY, 14627, USA., Tabei SMA; Physics Department, University of Northern Iowa, Cedar Falls, IA, 50614, USA., Banerjee S; Department of Physics and Astronomy, Institute for the Physics of Living Systems, University College London, Gower Street, London, WC1E 6BT, UK. shiladitya.banerjee@ucl.ac.uk., Murrell MP; Department of Physics, Yale University, 217 Prospect Street, New Haven, CT, 06511, USA. michael.murrell@yale.edu.; Systems Biology Institute, Yale University, 850 West Campus Drive, West Haven, CT, 06516, USA. michael.murrell@yale.edu.; Department of Biomedical Engineering, Yale University, 55 Prospect Street, New Haven, CT, 06511, USA. michael.murrell@yale.edu.

Publikováno v: Nature communications [Nat Commun] 2018 Nov 23; Vol. 9 (1), pp. 4948. Date of Electronic Publication: 2018 Nov 23.

Disordered actomyosin networks are sufficient to produce cooperative and telescopic contractility.

Autor: Linsmeier I; Department of Biomedical Engineering, Yale University, 55 Prospect Street, New Haven, Connecticut 06520, USA.; Systems Biology Institute, Yale University, 850 West Campus Drive, West Haven, Connecticut 06516, USA., Banerjee S; James Franck Institute, University of Chicago, Chicago, Illinois 60637, USA., Oakes PW; James Franck Institute, University of Chicago, Chicago, Illinois 60637, USA., Jung W; School of Mechanical Engineering, 585 Purdue Mall, Purdue University, West Lafayette, Indiana 47907, USA., Kim T; Weldon School of Biomedical Engineering, 206 S Martin Jischke Drive, Purdue University, West Lafayette, Indiana 47907, USA., Murrell MP; Department of Biomedical Engineering, Yale University, 55 Prospect Street, New Haven, Connecticut 06520, USA.; Systems Biology Institute, Yale University, 850 West Campus Drive, West Haven, Connecticut 06516, USA.

Publikováno v: Nature communications [Nat Commun] 2016 Aug 25; Vol. 7, pp. 12615. Date of Electronic Publication: 2016 Aug 25.

Myosin and α-actinin regulation of stress fiber contractility under tensile stress.

Autor: Ni, Haoran¹ (AUTHOR), Ni, Qin² (AUTHOR) qni4@jhu.edu, Papoian, Garegin A.^1,3 (AUTHOR), Trache, Andreea^4,5 (AUTHOR), Jiang, Yi⁶ (AUTHOR) yjiang12@gsu.edu

Publikováno v: Scientific Reports. 5/29/2023, Vol. 13 Issue 1, p1-13. 13p.

Prebiotic decluttering: the thermodynamic tail-wind to asymmetric autocatalysis.

Autor: Perović, Slobodan¹ (AUTHOR) sperovic@f.bg.ac.rs

Publikováno v: International Journal of Astrobiology. Feb2023, Vol. 22 Issue 1, p15-32. 18p.