Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Linshan Hu"'
Autor:
Linshan Hu, Sweta Misra, Baktiar Karim, Skyler Kuhn, Jacqueline Salotti, Srikanta Basu, Nancy Martin, Karen Saylor, Peter F. Johnson
The tumor suppressor p53 triggers senescence in response to oncogenic stress in primary cells. However, the mechanisms by which tumor cells retaining p53 bypass senescence are not fully understood. Here we report that p53 cytostatic activity is inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::145910cfa3fcadee068ac39e43dea46f
https://doi.org/10.1101/2022.04.04.487038
https://doi.org/10.1101/2022.04.04.487038
Autor:
Jacqueline Salotti, Baktiar Karim, Sweta Misra, Linshan Hu, Srikanta Basu, Nancy Martin, Brian T. Luke, Karen Saylor, Thorkell Andresson, David A. Scheiblin, Stephen Lockett, Lino Tessarollo, Peter F. Johnson
C/EBPβ is a potent regulator of RAS-induced senescence (RIS) and the SASP. C/EBPβ is post- translationally activated in RIS cells by the effector kinases ERK1/2 and CK2, but in tumor cells activation is suppressed by the CEBPB 3’UTR. 3′UTR regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55ed09d3228d7898093bd7b9a2daf8a8
https://doi.org/10.1101/2022.03.29.486281
https://doi.org/10.1101/2022.03.29.486281
Publikováno v:
Journal of Physics: Conference Series. 1650:022064
This paper studies and designs a high-precision resistance inductance and capacitance measuring instrument based on single-chip microcomputer. It uses MAX038 monolithic voltage control function generator to generate high-precision sine wave signal fl
Autor:
Hu Chen, Hongbin Ji, Tao Lv, Han You, Yujun Zhang, Haibo Zhang, Junfeng Wu, Shan Liang, Linshan Hu, Min Wu, Zhi-Xiong Jim Xiao, Shengnan Sun, Deshi Chen, Johann Bergholz
Publikováno v:
Proceedings of the National Academy of Sciences. 114
Activation of phosphatidylinositol 3 kinase (PI3K), Ras, and Her2 signaling plays a critical role in cancer development. Hotspot constitutive activating mutations in oncogenes, such as PIK3CA encoding the p110α catalytic subunit or RAS, as well as o
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Antarctic krill oil (KO) prepared using supercritical carbon dioxide extraction and characterized using gas chromatography-mass spectrometry was used to investigate its preventive effect on ethanol-induced gastric tissue damage in a rat model in vivo
Externí odkaz:
https://doaj.org/article/3410c24ac56e4644abbc9f3ecb4459a7
Publikováno v:
Molecular & Cellular Oncology. 3:e1106635
MDM2 (mouse double minute 2 homolog) and MDMX (double minute X human homolog, also known as MDM4) are critical negative regulators of tumor protein p53. Our recent work shows that MDMX binds to and promotes degradation of retinoblastoma protein (RB)
Autor:
Qionghui Cai, Na Xu, Yan He, Jiamin Zhu, Fenfen Ye, Zhi Luo, Ruojun Lu, Linshan Huang, Feiyang Zhang, Jiang-Fan Chen, Yan Li
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1365 (2023)
Parkinson’s disease (PD) is characterized pathologically by abnormal aggregation of alpha-synuclein (α-Syn) in the brain and clinically by fine movement deficits at the early stage, but the roles of α-Syn and associated neural circuits and neurom
Externí odkaz:
https://doaj.org/article/314ee65dd9f24e91a69ef45d050f094a
Autor:
Linshan Hu, Shan Liang, Hu Chen, Tao Lv, Junfeng Wu, Chen, Deshi, Min Wu, Shengnan Sun, Haibo Zhang, Han You, Hongbin Ji, Yujun Zhang, Bergholz, Johann, Zhi-Xiong Jim Xiao
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 5/16/2017, Vol. 114 Issue 20, pE3964-E3973, 10p
Publikováno v:
IEEE Access, Vol 6, Pp 69335-69341 (2018)
The augmented Zagreb index (AZI), a variant of the well-known atom-bond connectivity (ABC) index, was shown to have the best predicting ability for a variety of physicochemical properties among several tested vertex-degree-based topological indices.
Externí odkaz:
https://doaj.org/article/3270e91a3b98473890b7ada3a6ef2c87
Autor:
Yan Li, Xinran Pan, Yan He, Yang Ruan, Linshan Huang, Yuling Zhou, Zhidong Hou, Chaoxiang He, Zhe Wang, Xiong Zhang, Jiang-Fan Chen
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The balance and smooth shift between flexible, goal-directed behaviors and repetitive, habitual actions are critical to optimal performance of behavioral tasks. The striatum plays an essential role in control of goal-directed versus habitual behavior
Externí odkaz:
https://doaj.org/article/5879df5576f64cdcbc48e0f2dd25d61f