Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Linsey E. S. de Groot"'
Autor:
Linsey E. S. de Groot, Dingyu Liu, Barbara S. Dierdorp, Niki Fens, Marianne A. van de Pol, Peter J. Sterk, Wim Kulik, Miriam E. Gerlofs-Nijland, Flemming R. Cassee, Elena Pinelli, René Lutter
Publikováno v:
Environmental Health, Vol 19, Iss 1, Pp 1-10 (2020)
Abstract Background Asthma patients suffer from periodic acute worsening of symptoms (i.e. loss of asthma control or exacerbations), triggered by a variety of exogenous stimuli. With the growing awareness that air pollutants impact respiratory diseas
Externí odkaz:
https://doaj.org/article/fd805339cf214428b826258cf765ecc1
Autor:
René Lutter, Peter J. Sterk, Barbara Dierdorp, Tamara Dekker, Marianne A. van de Pol, Christof J. Majoor, Wim Kulik, Niki Fens, Jörg Hamann, Linsey E. S. de Groot
Publikováno v:
Chest, 157(1), 16-25. American College of Chest Physicians
Background Loss of asthma control and asthma exacerbations are associated with increased sputum eosinophil counts. However, whether eosinophils, or the also present neutrophils, actively contribute to the accompanying inflammation has not been extens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce70fe588060eb1ae202e5e68edce8a
http://www.scopus.com/inward/record.url?scp=85076825895&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85076825895&partnerID=8YFLogxK
Publikováno v:
Current Opinion in Pulmonary Medicine
Current opinion in pulmonary medicine, 26(1), 62-68. Lippincott Williams and Wilkins
Current opinion in pulmonary medicine, 26(1), 62-68. Lippincott Williams and Wilkins
PURPOSE OF REVIEW: Asthma is a chronic inflammatory disease in which changes in macrophage polarization have been shown to contribute to the pathogenesis. The present review discusses the contribution of changes in macrophage function to asthma relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c75981af9567b54bed75254858dfab
https://doi.org/10.1097/mcp.0000000000000647
https://doi.org/10.1097/mcp.0000000000000647
Autor:
Linsey E. S. de Groot, Barbro N. Melgert, Jörg Hamann, T. Anienke van der Veen, René Lutter, Fernando O. Martinez
Publikováno v:
American Journal of Physiology - Lung Cellular and Molecular Physiology. 316(2):L369-L384
Oxidative stress is a common feature of obstructive airway diseases like asthma and chronic obstructive pulmonary disease (COPD). Lung macrophages are key innate immune cells that can generate oxidants and are known to display aberrant polarization p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8476099e97950d27443c2cb2610e8c0
http://www.scopus.com/inward/record.url?scp=85060951919&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85060951919&partnerID=8YFLogxK
Autor:
Eduard Post, Corry-Anke Brandsma, René Lutter, Barbro N. Melgert, Linsey E. S. de Groot, Ken R. Bracke, Irene H. Heijink, Maarten van den Berge, T. Anienke van der Veen, Mirjam P. Roffel, Tania Maes, Marina H. de Jager, Ilse M. Boudewijn
Publikováno v:
European Respiratory Journal, 54. EUROPEAN RESPIRATORY SOC JOURNALS LTD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ba936d3255170c3e2e0fd347a4ba4b
https://hdl.handle.net/11370/26eaf657-4dbe-4dd2-8fa9-821737eb444f
https://hdl.handle.net/11370/26eaf657-4dbe-4dd2-8fa9-821737eb444f
Autor:
Marina H. de Jager, René Lutter, Barbro N. Melgert, Linsey E. S. de Groot, Eduard Post, T. Anienke van der Veen
Publikováno v:
Airway Cell Biology and Immunopathology.
Exacerbations of COPD can be triggered by viral infections. Macrophages are involved in airway inflammation in COPD and in limiting inflammatory events in the lung. These opposing tasks are handled by differentially polarized macrophages. MHCII-high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::306bd298680e93ec92672c2c93720452
https://doi.org/10.1183/23120541.lungscienceconference-2019.pp219
https://doi.org/10.1183/23120541.lungscienceconference-2019.pp219
Autor:
René Lutter, Suzanne M. Bal, Jörg Hamann, Yanaika S. Sabogal Piñeros, Peter J. Sterk, Marianne A. van de Pol, Wim Kulik, Linsey E. S. de Groot
Publikováno v:
Clinical and experimental allergy, 49(6), 929-931. Wiley-Blackwell
Clinical and Experimental Allergy
Clinical and Experimental Allergy
Loss of asthma control and asthma exacerbations are predominantly triggered by respiratory viral infections and characterized by eosinophilic airway inflammation and increased oxidative stress. Production of reactive oxygen species is a key feature o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11f01b2e5f77a64cf100ff906ddf0809
https://doi.org/10.1183/23120541.lungscienceconference-2019.pp232
https://doi.org/10.1183/23120541.lungscienceconference-2019.pp232