Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Linsey, Gold"'
Autor:
Christy Kesslering, Charles E. Cox, Sandra Templeton, Eric J. Brown, Anushka Patel, Chirag Shah, Troy Bremer, Rakesh R. Patel, Robert Gabordi, Rachel Rabinovich, Pat Whitworth, Linsey Gold, Lee B. Riley, Shawna C. Willey, David Rock, Lonika Majithia, Naamit K. Gerber, James Pellicane, Sadia Khan, Frank A. Vicini, Steve Shivers, Sheree Brown, Fredrik Wärnberg
Publikováno v:
Annals of Surgical Oncology
Background The role of radiation therapy (RT) following breast-conserving surgery (BCS) in ductal carcinoma in situ (DCIS) remains controversial. Trials have not identified a low-risk cohort, based on clinicopathologic features, who do not benefit fr
Autor:
E Shelley, Hwang, Peter, Beitsch, Peter, Blumencranz, David, Carr, Anees, Chagpar, Lynne, Clark, Nayana, Dekhne, Daleela, Dodge, Donna L, Dyess, Linsey, Gold, Stephen, Grobmyer, Kelly, Hunt, Stephen, Karp, Beth-Ann, Lesnikoski, Irene, Wapnir, Barbara L, Smith, Sean, Madden
Publikováno v:
JAMA surgery. 157(7)
Positive margins following breast-conserving surgery (BCS) are often identified on standard pathology evaluation. Intraoperative assessment of the lumpectomy cavity has the potential to reduce residual disease or reexcision rate following standard of
Abstract PS8-30: Longitudinal clinical outcomes of a multi-center universal genetic testing registry
Autor:
Melissa Trudrung, Max Brown, Ian Grady, Barry P. Rosen, Mary Kay Hardwick, Rakesh Patel, Edward D. Esplin, Sarah M. Nielsen, Chloe Wernecke, Gia Compagnoni, Linsey Gold, Robert L. Nussbaum, Peter D. Beitsch, Richard J. C. Brown, Pat Whitworth
Publikováno v:
Cancer Research. 81:PS8-30
Background: Growing evidence indicates that restrictive criteria for determining eligibility of breast cancer patients for germline genetic testing (e.g. NCCN, etc.) can missa significant number who may benefit from testing. However, the clinical uti
Autor:
David P. Ondrula, Kevin S. Hughes, David M. Euhus, John F. Sandbach, S. Dwight Lyons, Yuxi Liu, Alan Semine, Melford Allan C. Lazarte, Linda Ann Smith, Kanhua Yin, Linsey Gold, Gayle Patel, Danielle Braun, Basanta Lamichhane, Eric J. Brown, Pat Whitworth, Richard H. Kanak, Gia Compagnoni, Giovanni Parmigiani, Barry Rosen, Colleen App
Publikováno v:
Annals of Surgical Oncology. 27:2212-2220
The classification of germline variants may differ between labs and change over time. We apply a variant harmonization tool, Ask2Me VarHarmonizer, to map variants to ClinVar and identify discordant variant classifications in a large multipractice var
Autor:
Kate Smith, Jorge Ferrer, David Carr, Peter Blumencranz, Daleela Dodge, Nayana Dekhne, Irene Wapnir, Kelly Hunt, Linsey Gold, Stephanie Valente, Peter Beitsch, Donna Dyess, Shelly Hwang, Lynne Clark, Beth-Ann Lesnikoski, Anees Chagpar, Stephen Karp, Brian Schlossberg, Livia Gjylameti, Barbara Smith
Publikováno v:
Cancer Research. 80:OT3-06
Background: Standard surgical techniques result in positive lumpectomy margins 20-40% of the time. These positive margins require surgical re-excision which places significant burden on the healthcare system and patients. The LUM Imaging System consi
Autor:
Lynne Clark, Barbara L. Smith, Stephen E. Karp, Katherine Clegg Smith, Irene Wapnir, Sean Madden, Peter D. Beitsch, Stephanie A. Valente, W. David Lee, Donna Lynn Dyess, Nayana Dekhne, Beth-Ann Lesnikoski, Jorge Ferrer, Anees B. Chagpar, Peter W. Blumencranz, Kelly K. Hunt, David Carr, Brian Schlossberg, S Hwang, Linsey Gold, Daleela Dodge, Manna Chang, David B. Strasfeld
Publikováno v:
Cancer Research. 80:P1-20
Background: Standard surgical techniques result in positive lumpectomy margins 20-40% of the time. These positive margins require surgical re-excision which places significant burden on the healthcare system and patients. The LUM Imaging System consi
Autor:
Antonio Carlos Sánchez Ruiz, Laura Lee, Linsey Gold, Rakesh Patel, Paul L. Baron, Peter D. Beitsch, Pat Whitworth, Richard J. C. Brown
Publikováno v:
Cancer Research. 80:P2-16
Background: Molecular genomic profiles are increasingly used to guide treatment of refractory cancers and are on the forefront of personalized medicine for select patients. The neoadjuvant chemotherapy (NAC) setting provides a meaningful opportunity
Autor:
Pat W, Whitworth, Peter D, Beitsch, Rakesh, Patel, Barry, Rosen, Gia, Compagnoni, Paul L, Baron, Rache, Simmons, Eric A, Brown, Linsey, Gold, Dennis, Holmes, Linda Ann, Smith, Michael, Kinney, Ian, Grady, Patricia, Clark, Karen, Barbosa, Samuel, Lyons, Lee, Riley, Cynara, Coomer, Lisa, Curcio, Antonio, Ruiz, Sadia, Khan, Heather, MacDonald, Kevin, Hughes, Mary Kay, Hardwick, Brandie, Heald, Sandra B, Munro, Sarah M, Nielsen, Edward D, Esplin
Publikováno v:
JAMA Network Open. 5:e2232787
ImportanceNational Comprehensive Cancer Network guidelines currently recommend germline testing for high-risk genes in selected patients with breast cancer. The clinical utility of recommending testing all patients with breast cancer with multigene p
Autor:
Kenneth R Tomkovich, Susan A Seedman, Richard E. Fine, Susan K. Boolbol, Sheldon Feldman, Lydia Hernandez, Jill R. Dietz, Lisa D. Curcio, Karen S Columbus, Linda K Han, Andrew S Kenler, Michael S. Sabel, Eric R. Manahan, Rache M. Simmons, Margaret Chen, Richard C. Gilmore, Linsey Gold, Rashmi P Vaidya, Alexander B Sevrukov, Hussein D Aoun, Randy D Hicks, Noam A VanderWalde, Michael P Berry
Publikováno v:
Annals of surgical oncology. 28(10)
The ICE3 trial is designed to evaluate the safety and efficacy of breast cryoablation, enabling women older than 60 years with low-risk early-stage breast cancers to benefit from a nonsurgical treatment and to avoid the associated surgical risks. The
Autor:
Edward D. Esplin, Sadia Khan, Barry P. Rosen, Robert L. Nussbaum, Linsey Gold, Linda Ann Smith, Michael Kinney, Patricia Clark, Gia Compagnoni, Rache M. Simmons, Sam Lyons, Dennis R. Holmes, Cynara Coomer, Shan Yang, Mary Kay Hardwick, Heather MacDonald, Karen Barbosa, Peter D. Beitsch, Eric J. Brown, Lisa D. Curcio, Pat Whitworth, Paul L. Baron, Ian Grady, Kevin S. Hughes, Rakesh Patel, Lee B. Riley, Tony Ruiz
Publikováno v:
Cancer Research. 80:P6-08
Background: HBOC testing guidelines were established to identify patients with clinically actionable variants and limit economic burden. We report the impact of germline results on health outcome based on clinical decision making and treatment interv