Analysis of a platform for exchange of patients’ expertise in TTFields practice to improve quality-of-life in high-grade glioma patients

Autor: Keßler, AF, Weiland, J, Dufner, V, Lilla, N, Linsenmann, T, Westermaier, T, Hagemann, C, Ernestus, RI, Löhr, M, Jentschke, E

Publikováno v: 71. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 9. Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie; 20200621-20200624; sine loco [digital]; DOCV018 /20200626/

Objective: Glioblastoma (GBM) Patients and their Relatives (PaR) face tremendous distress and psychological burden due to limited survival and neurological/neuropsychological deficits. Tumor Treating Fields (TTFields, alternating electric fields at 2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0faa4dc8be52fa960207b9dda1435428

Expression of activating transcription factor 5 (ATF5) is increased in astrocytomas of different WHO grades and correlates with survival of glioblastoma patients

Autor: Feldheim J, Kessler AF, Schmitt D, Wilczek L, Linsenmann T, Dahlmann M, Monoranu CM, Ernestus RI, Hagemann C, Löhr M

Publikováno v: OncoTargets and Therapy, Vol Volume 11, Pp 8673-8684 (2018)

Jonas Feldheim,1 Almuth F Kessler,1 Dominik Schmitt,1 Lara Wilczek,1 Thomas Linsenmann,1 Mathias Dahlmann,2,3 Camelia M Monoranu,4 Ralf-Ingo Ernestus,1 Carsten Hagemann,1,* Mario Löhr1,* 1Department of Neurosurgery, Tumorbiology Labo­ratory, Univer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::28e288e679a998cb7d0545df30882a78
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-177541

Activating transcription factor 5 – a new therapeutic target for treatment of astrocytomas?

Autor: Feldheim, J, Keßler, AF, Hagemann, C, Linsenmann, T, Ernestus, RI, Löhr, M

Publikováno v: 67. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 1. Joint Meeting mit der Koreanischen Gesellschaft für Neurochirurgie (KNS); 20160612-20160615; Frankfurt am Main; DOCMI.02.08 /20160608/

Objective: Activating transcription factor 5 (ATF5) is a widely expressed basic leucine zipper protein, that is known to suppress differentiation of neuroprogenitor cells into neurons or glia in the normal brain (NB) and has been reported to be overe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d1541d177b0074e07ea401cfb79c9ab

Long-term tumor control of spinal dissemination of cerebellar glioblastoma multiforme by combined adjuvant bevacizumab chemotherapy

Autor: Linsenmann, T, Monoranu, CM, Westermaier, T, Hagemann, C, Kessler, AF, Ernestus, RI, Löhr, M

Publikováno v: 65. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC); 20140511-20140514; Dresden; DOCP 019 /20140513/

Objective: In this case study, we report of a female patient with an exophytic glioblastoma multiforme (GBM) arising from the cerebellar tonsil and a secondary spinal manifestation. Furthermore, the tumor showed no MGMT promotor-hypermethylation and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b40b372bf5af59eb620097beee14f4

Reduction and delay of tumor growth by systemic application of rhGM-CSF in orthotopic rodent glioma model

Autor: Linsenmann, T, Löhr, M, Hagemann, C, Kessler, A, Ernestus, RI, Vince, GH

Publikováno v: 64. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC); 20130526-20130529; Düsseldorf; DOCMI.13.12 /20130521/

Objective: Tumor associated macrophages (TAM) arising from both activated microglia and systemic macrophages are supposed to enhance glioma growth and invasion. However, our previous finding that a depletion of systemic macrophages by clodronate dist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::036906af877dd9fdd9cf8fc319fbe005