Zobrazeno 1 - 10
of 355
pro vyhledávání: '"Linsen, Li"'
Autor:
Bin Wei, Yuhui Fu, Xiuzhi Li, Fang Chen, Yiqing Zhang, Hanmo Chen, Mindan Tong, Linsen Li, Yi Pan, Shen Zhang, She Chen, Xiaoxia Liu, Qing Zhong
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-17 (2024)
Abstract Macroautophagy is a process that cells engulf cytosolic materials by autophagosomes and deliver them to lysosomes for degradation. The biogenesis of autophagosomes requires ATG2 as a lipid transfer protein to transport lipids from existing m
Externí odkaz:
https://doaj.org/article/6f39b507cc2f4e23aacc3b6aa6551606
Autor:
Yuhui Fu, Binbin Ding, Xiaoxia Liu, Shangang Zhao, Fang Chen, Linsen Li, Yi Zhu, Jingxuan Zhao, Zhen Yuan, Yafeng Shen, Chaofeng Yang, Mengle Shao, She Chen, Perry E. Bickel, Qing Zhong
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-22 (2023)
Abstract Lipid droplets (LDs) are dynamic lipid storage organelles that can sense and respond to changes in systemic energy balance. The size and number of LDs are controlled by complex and delicate mechanisms, among which, whether and which SNARE pr
Externí odkaz:
https://doaj.org/article/d73b0f5e6c844c74ad725a1cd344b84d
Autor:
Shen Zhang, Mindan Tong, Denghao Zheng, Huiying Huang, Linsen Li, Christian Ungermann, Yi Pan, Hanyan Luo, Ming Lei, Zaiming Tang, Wan Fu, She Chen, Xiaoxia Liu, Qing Zhong
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract The multi-subunit homotypic fusion and vacuole protein sorting (HOPS) membrane-tethering complex is required for autophagosome-lysosome fusion in mammals, yet reconstituting the mammalian HOPS complex remains a challenge. Here we propose a
Externí odkaz:
https://doaj.org/article/9bd957d201cc4777b41407b4eef50660
Publikováno v:
GeoHazards, Vol 4, Iss 3, Pp 302-315 (2023)
To reduce the significant losses caused by slope failures and landslides, it is of great significance to detect and predict these disasters scientifically. This study focused on Huangdao District of Qingdao City in Shandong Province, using the improv
Externí odkaz:
https://doaj.org/article/7a40da3832bb453dadd3dcb08bc2ee33
Publikováno v:
Molecules, Vol 29, Iss 13, p 3013 (2024)
In this study, a self-responsive fluorescence aptasensor was established for the determination of lactoferrin (Lf) in dairy products. Herein, the aptamer itself functions as both a recognition element that specifically binds to Lf and a fluorescent s
Externí odkaz:
https://doaj.org/article/452910e43798416891aca1e1f6d86ef9
Publikováno v:
IET Intelligent Transport Systems, Vol 17, Iss 3, Pp 522-533 (2023)
Abstract Pixel segmentation is one of the most commonly used deep learning methods for modern lane line detection. Although deep segmentation outperforms traditional methods, there are two main problems: slow speed and limited receptive field. In res
Externí odkaz:
https://doaj.org/article/f496c14ea87a444795fbce8809e62a76
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The vanishing point (VP) is particularly important road information, which provides an important judgment criterion for the autonomous driving system. Existing vanishing point detection methods lack speed and accuracy when dealing with real
Externí odkaz:
https://doaj.org/article/f543805eb3594e6fb9ab89731fef8912
Publikováno v:
Batteries, Vol 10, Iss 3, p 109 (2024)
The improvement of fast-charging capabilities for lithium-ion batteries significantly influences the widespread application of electric vehicles. Fast-charging performance depends not only on materials but also on the battery’s inherent structure a
Externí odkaz:
https://doaj.org/article/d8e9e16965854e4b833f9dffbca5a9c7
Autor:
Houfu Leng, Hanlin Zhang, Linsen Li, Shuhao Zhang, Yanping Wang, Selina J. Chavda, Daria Galas-Filipowicz, Hantao Lou, Adel Ersek, Emma V. Morris, Erdinc Sezgin, Yi-Hsuan Lee, Yunsen Li, Ana Victoria Lechuga-Vieco, Mei Tian, Jian-Qing Mi, Kwee Yong, Qing Zhong, Claire M. Edwards, Anna Katharina Simon, Nicole J. Horwood
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Here, the authors show that the glycosylceramide synthesis inhibitor and FDA approved drug Eliglustat inhibits autophagic degradation of TRAF3 which is a key step for osteoclast differentiation and thereby improves myeloma bone lesions.
Externí odkaz:
https://doaj.org/article/d3f4b2b671d34e5f9416142c53caf80d
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-14 (2022)
Abstract Urban lakes provide important ecological services to local communities, such as flood mitigation, biodiversity, and recreation. With rapid urbanization, urban lakes are significantly affected by socio-economic development and urgently need a
Externí odkaz:
https://doaj.org/article/a5b335b1d1614bd8a0b9eb479eea6e5e