Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Lino Colombo"'
Publikováno v:
Synthesis. 53:785-804
Enyne metathesis reactions are powerful tools for the preparation of a wide range of synthetic and natural chemical substances with increasing efficiency and environmental sustainability. The driving force of the reaction is the formation of a stable
Publikováno v:
European Journal of Organic Chemistry. 2020:3568-3575
Publikováno v:
European Journal of Organic Chemistry. 2019:732-741
Publikováno v:
The Journal of Organic Chemistry. 82:11091-11101
7,5-Fused azabicycloalkane scaffolds, carrying a quaternary stereocenter at C3 position of the lactam ring, can act as effective reverse-turn mimics and have proven to be useful intermediates for the preparation of Arg-Gly-Asp (RGD)-based cyclopentap
Publikováno v:
European Journal of Organic Chemistry. 2017:2964-2970
We report a fast one-pot protocol for the direct vinylation of azlactones [oxazol-5-(4H)-ones] by using as a key step an aldol addition with 2-(phenylselenenyl)acetaldehyde followed by dehydroxyselenation. The acid hydrolysis of the oxazolone ring ga
Publikováno v:
The Journal of organic chemistry. 84(23)
Azabicyclo[4.3.0]- and [5.3.0]alkanone amino acid derivatives were easily prepared by submitting the same starting dipeptide to a direct ring-closing enyne metathesis or an ethylene-mediated cross-enyne metathesis/ring-closing metathesis, respectivel
Autor:
Sergio Schinelli, Antonio Daga, Massimo Serra, Mayra Paolillo, Emilio Ciusani, Marisa Carlotta Galiazzo, Lino Colombo
Publikováno v:
International Journal of Oncology.
The malignancy of glioblastoma (GB) is primarily due to the ability of glioma cancer stem cells (GSC) to disseminate into surrounding brain tissues, despite surgery and chemotherapy, and to form new tumoral masses. Members of the RGD-binding integrin
Autor:
Laura Belvisi, Massimo Serra, Elena Giulia Peviani, Lino Colombo, Marcello Di Giacomo, Simone Maria Tambini
Publikováno v:
European Journal of Organic Chemistry. 2015:7557-7570
In this paper we report the synthesis of new azabicycloalkane scaffolds, which could be exploited to obtain cRGD-based bioconjugates that may find promising application for targeted drug delivery, theranostic, and general cancer-cell labeling. By exp
Autor:
Sergio Schinelli, Massimo Serra, Yuly Sanchez-Hernandez, Lino Colombo, Mayra Paolillo, Emilio Ciusani, Daniela Curti, Marika A. Russo
Publikováno v:
International Journal of Oncology
In cancer cells integrins modulate important cellular events that regulate the metastasic cascade which involves detachment from the tumor mass, dissemination and attachment to the oncogenic niche. The α5β1, αvβ3 and αvβ5 integrins are widely e
Autor:
Carlos Roberto Altafini, Augusto Leandro Moresco, Adelair Lino Colombo, Paulo Roberto Wander, Diogo Lusa
Publikováno v:
Biomass and Bioenergy. 35:3995-4000
Experimental results are presented for a compression ignition engine with one cylinder refrigerated by air, fueled with soy straight vegetable oil (SVO), filtered at 500 nm and blended with diesel at volume percentages of 10, 30, 50, 70 and 100%. Per