Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Linnette Capo"'
Autor:
Mike Mattie, Ashley Christensen, Mi Sook Chang, William Yeh, Suzanne Said, Yuriy Shostak, Linnette Capo, Alla Verlinsky, Zili An, Ingrid Joseph, Yi Zhang, Sathish Kumar-Ganesan, Karen Morrison, David Stover, Pia Challita-Eid
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 10, Pp 1138-1150 (2013)
Preclinical evaluation of novel cancer agents requires models that accurately reflect the biology and molecular characteristics of human tumors. Molecular profiles of eight pancreatic ductal adenocarcinoma patient tumors were compared to correspondin
Externí odkaz:
https://doaj.org/article/831892b326e84391aa8e08fefdb77db2
Autor:
David R. Stover, Dennis Benjamin, Pia Challita-Eid, Ingrid B.J. Joseph, Fernando Doñate, Daniel S. Pereira, Ying Li, Jeffrey Coleman, Steven Duniho, Ruth Moser, Faisal Malik, Claudia Guevara, Hector Aviña, Rossana Nadell, Jimmy Ou, Monica Leavitt, Alla Verlinsky, Linnette Capo, Zili An, Karen Morrison, Kendall Morrison, Arthur Raitano, Michael Mattie
Here, we report the development of an antibody–drug conjugate, ASG-5ME, which targets the solute carrier receptor SLC44A4. SLC44A4 is a member of a family of putative choline transporters that we show to be markedly upregulated in a variety of epit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::510fb86e62a3f121e464a29893f6e996
https://doi.org/10.1158/1535-7163.c.6538426.v1
https://doi.org/10.1158/1535-7163.c.6538426.v1
Autor:
David R. Stover, Dennis Benjamin, Pia Challita-Eid, Ingrid B.J. Joseph, Fernando Doñate, Daniel S. Pereira, Ying Li, Jeffrey Coleman, Steven Duniho, Ruth Moser, Faisal Malik, Claudia Guevara, Hector Aviña, Rossana Nadell, Jimmy Ou, Monica Leavitt, Alla Verlinsky, Linnette Capo, Zili An, Karen Morrison, Kendall Morrison, Arthur Raitano, Michael Mattie
Figure S1. Proteolytic release of MMAE from ASG-5ME; Figure S2. SLC44A4 RNA expression in normal and tumor specimens from combined Oncomine data sets; Figure S3: Expression of SLC44A4 in OVCAR-5 cells determined by FACS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed5c9b6bfa05d8cb976b95011b8f210
https://doi.org/10.1158/1535-7163.22506523
https://doi.org/10.1158/1535-7163.22506523
Autor:
David R. Stover, Karen Morrison, Daniel S. Pereira, Ingrid B.J. Joseph, Fernando Doñate, Hector Aviña, Alla Verlinsky, Linnette Capo, Josh T. Snyder, Dawn Ratay Lortie, Wendy Liu, Joseph D. Abad, Peng Yang, Zili An, Arthur Raitano, Pia M. Challita-Eid, Kendall Morrison
SLITRK6 is a member of the SLITRK family of neuronal transmembrane proteins that was discovered as a bladder tumor antigen using suppressive subtractive hybridization. Extensive immunohistochemistry showed SLITRK6 to be expressed in multiple epitheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c7e29afe45a3470c1c88725becfe7e
https://doi.org/10.1158/1535-7163.c.6537600
https://doi.org/10.1158/1535-7163.c.6537600
Autor:
David R. Stover, Karen Morrison, Daniel S. Pereira, Ingrid B.J. Joseph, Fernando Doñate, Hector Aviña, Alla Verlinsky, Linnette Capo, Josh T. Snyder, Dawn Ratay Lortie, Wendy Liu, Joseph D. Abad, Peng Yang, Zili An, Arthur Raitano, Pia M. Challita-Eid, Kendall Morrison
Details on how the IHC reagent reported in this paper was generated and validated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a45130ccf051fe615d169867a44dd0d
https://doi.org/10.1158/1535-7163.22504038
https://doi.org/10.1158/1535-7163.22504038
Autor:
David R. Stover, Pia M. Challita-Eid, Daniel S. Pereira, Ingrid B.J. Joseph, John Atkinson, Daulet Satpayev, Wendy Liu, Rossana Nadell, Faisal Malik, Yuriy Shostak, Ryuichi Moriya, Jimmy Ou, Peng Yang, Karen Morrison, Sher Karki, Hector Aviña, Linnette Capo, Zili An, Kendall Morrison, Arthur Raitano, Fernando Doñate
Supplemental Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071a72a470db5adede0722ce6e0e19a7
https://doi.org/10.1158/1078-0432.22460346
https://doi.org/10.1158/1078-0432.22460346
Autor:
Fernando Doñate, David R. Stover, Brian A. Mendelsohn, Roland Luethy, Sung-Ju Moon, Josh Snyder, Linnette Capo, René Hubert, Hector Aviña, Sher Karki, Pia Challita-Eid, Faisal Malik, Jeffrey Coleman, Karen Morrison, Peng Yang, Jimmy Ou, Jenny Nater, Zhilan Zeng, Sara Gulesserian, John Atkinson, Hui Zhao
AGS-16C3F is an antibody–drug conjugate (ADC) against ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3) containing the mcMMAF linker-payload currently in development for treatment of metastatic renal cell carcinoma. AGS-16C3F and other ADC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15490f6d4322c9192d3919e4ad7ff9a9
https://doi.org/10.1158/0008-5472.c.6510380.v1
https://doi.org/10.1158/0008-5472.c.6510380.v1
Autor:
Fernando Doñate, David R. Stover, Brian A. Mendelsohn, Roland Luethy, Sung-Ju Moon, Josh Snyder, Linnette Capo, René Hubert, Hector Aviña, Sher Karki, Pia Challita-Eid, Faisal Malik, Jeffrey Coleman, Karen Morrison, Peng Yang, Jimmy Ou, Jenny Nater, Zhilan Zeng, Sara Gulesserian, John Atkinson, Hui Zhao
Supplemental tables 1-5: Table 1: Characteristics of peptide modified ADCs tested and IC50 in the HCEC and KU812 assays. Table 2: Characteristics. of PEG modified ADCs tested and data in the HCEC and KU812 assays. Table 3: Characteristics of mutated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7610130a3c9e9e7370a263155dfda9
https://doi.org/10.1158/0008-5472.22419443
https://doi.org/10.1158/0008-5472.22419443
Autor:
David R. Stover, Pia M. Challita-Eid, Daniel S. Pereira, Ingrid B.J. Joseph, John Atkinson, Daulet Satpayev, Wendy Liu, Rossana Nadell, Faisal Malik, Yuriy Shostak, Ryuichi Moriya, Jimmy Ou, Peng Yang, Karen Morrison, Sher Karki, Hector Aviña, Linnette Capo, Zili An, Kendall Morrison, Arthur Raitano, Fernando Doñate
Supplemental Table 1. Quantification of ENPP3 Expression in Various Carcinomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81085b4cbfb6ad90b94dc083d54e1849
https://doi.org/10.1158/1078-0432.22460334
https://doi.org/10.1158/1078-0432.22460334
Autor:
David R. Stover, Pia M. Challita-Eid, Daniel S. Pereira, Ingrid B.J. Joseph, John Atkinson, Daulet Satpayev, Wendy Liu, Rossana Nadell, Faisal Malik, Yuriy Shostak, Ryuichi Moriya, Jimmy Ou, Peng Yang, Karen Morrison, Sher Karki, Hector Aviña, Linnette Capo, Zili An, Kendall Morrison, Arthur Raitano, Fernando Doñate
Supplemental Figure 3A. Mapping of AGS16-7.8 binding to different ENNP3 domains. Supplemental Figure 3B. Western blots for mapping recognition of epitopes in ENPP3 ECD fragments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5387e7e6807e85977f0434db317afc
https://doi.org/10.1158/1078-0432.22460367
https://doi.org/10.1158/1078-0432.22460367