Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Linna R, Chen"'
Publikováno v:
Pharmaceutical Research. 17:619-624
Purpose. Nedocromil sodium (NS), which is used in the treatment ofreversible obstructive airway diseases, such as asthma, has been foundto exist in the following solid phases: the heptahemihydrate, thetrihydrate, a monohydrate, an amorphous phase, wh
Autor:
Linna R, Chen, James A, Wesley, Shobha, Bhattachar, Bienvenido, Ruiz, Korey, Bahash, Suresh R, Babu
Publikováno v:
Pharmaceutical research. 20(5)
To investigate the mechanism by which Tween 80 impedes the dissolution of CI-1041, a poorly water-soluble compound in its free form.Bulk powder and intrinsic dissolution (ID) of CI-1041 in 0.1 N HCl with various concentrations of Tween 80 were conduc
Publikováno v:
Journal of pharmaceutical sciences. 88(11)
Cromolyn sodium (CS, disodium cromoglycate) is an antiasthmatic and antiallergenic drug. The solid-state behavior of CS is still not completely understood. CS forms nonstoichiometric hydrates and sorbs and liberates water in a continuous manner, alth
Autor:
Linna R. Chen, David J.W. Grant
Publikováno v:
Pharmaceutical development and technology. 3(4)
The objectives of this study were to verify theoretically and experimentally that the Clausius-Clapeyron equation can be applied to a hydrate system, and to use this equation to predict the equilibrium water activity for a hydrate pair existing in eq