Zobrazeno 1 - 5
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pro vyhledávání: '"Linn Gazda"'
Autor:
Doris Hellerschmied, Anita Lehner, Nina Franicevic, Renato Arnese, Chloe Johnson, Antonia Vogel, Anton Meinhart, Robert Kurzbauer, Luiza Deszcz, Linn Gazda, Michael Geeves, Tim Clausen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Myosin, a motor protein essential for intracellular transport to muscle contraction, requires a chaperone UNC-45 for folding and assembly. Here authors use in vitro reconstitution and structural biology to characterize the interplay between UNC-45 an
Externí odkaz:
https://doaj.org/article/988d6ef9a9a34ef79788fa29755892f7
Autor:
Doris Hellerschmied, Max Roessler, Anita Lehner, Linn Gazda, Karel Stejskal, Richard Imre, Karl Mechtler, Alexander Dammermann, Tim Clausen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
The U-box ubiquitin ligase UFD-2 is one of the most abundant components of the ubiquitin proteasome system in muscle cells. Here the authors perform in vitro and in vivo experiments and show that UFD-2 has E3 ligase activity and that it ubiquitinates
Externí odkaz:
https://doaj.org/article/5d615670363d4e18b6f7439c5d092bfd
Autor:
Antonia Vogel, Luiza Deszcz, Anton Meinhart, Tim Clausen, Robert Kurzbauer, Linn Gazda, Doris Hellerschmied, Michael A. Geeves, Chloe A. Johnson, Nina Franicevic, Renato Arnese, Anita Lehner
Publikováno v:
Nature Communications
'Nature Communications ', vol: 10, pages: 4781-1-4781-14 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications 10(1), 4781 (2019). doi:10.1038/s41467-019-12667-8
'Nature Communications ', vol: 10, pages: 4781-1-4781-14 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications 10(1), 4781 (2019). doi:10.1038/s41467-019-12667-8
Myosin is a motor protein that is essential for a variety of processes ranging from intracellular transport to muscle contraction. Folding and assembly of myosin relies on a specific chaperone, UNC-45. To address its substrate-targeting mechanism, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfff0c0acff011837f4c324acd625e5e
https://kar.kent.ac.uk/77825/1/s41467-019-12667-8.pdf
https://kar.kent.ac.uk/77825/1/s41467-019-12667-8.pdf
Autor:
Thomas Löwe, Doris Hellerschmied, Felix Mueller-Planitz, Tim Clausen, Wojciech Pokrzywa, Ignasi Forné, Linn Gazda, Thorsten Hoppe
Publikováno v:
Cell
Summary The UCS (UNC-45/CRO1/She4) chaperones play an evolutionarily conserved role in promoting myosin-dependent processes, including cytokinesis, endocytosis, RNA transport, and muscle development. To investigate the protein machinery orchestrating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ed898a42cdfa61e34bfb3880edc5dca
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