Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities

Autor: Mallard, T. T., Linnér, R. K., Grotzinger, A. D., Sanchez-Roige, S., Seidlitz, J., Okbay, A., e Vlaming, R., Meddens, S. F. W., Bipolar Disorder Working Group of the PGC, Palmer, A. A., Davis, L. K., Tucker-Drob, E. M., Kendler, K. S., Keller, M. C., Koellinger, P. D., Harden, K. P., Gordon-Smith, Katherine, Perry, Amy, Jones, Lisa

Publikováno v: Cell Genomics, 2(6):100140
Bipolar Disorder Working Group of the Psychiatric Genomics Consortium 2022, ' Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities ', Cell Genomics, vol. 2, no. 6, 100140, pp. 1-19 . https://doi.org/10.1016/j.xgen.2022.100140
Cell Genomics, 2(6):100140. Cell Press
Cell Genomics, 2(6):100140, 1-19. Cell Press

A single dimension of general psychopathology, p , has been hypothesized to represent a general liability that spans multiple types of psychiatric disorders and non-clinical variation in psychiatric symptoms across the lifespan. We conducted genome-w

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https://doi.org/10.1016/j.xgen.2022.100140

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