Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities

Autor: Mallard, T. T., Linnér, R. K., Grotzinger, A. D., Sanchez-Roige, S., Seidlitz, J., Okbay, A., e Vlaming, R., Meddens, S. F. W., Bipolar Disorder Working Group of the PGC, Palmer, A. A., Davis, L. K., Tucker-Drob, E. M., Kendler, K. S., Keller, M. C., Koellinger, P. D., Harden, K. P., Gordon-Smith, Katherine, Perry, Amy, Jones, Lisa

Publikováno v: Cell Genomics, 2(6):100140
Bipolar Disorder Working Group of the Psychiatric Genomics Consortium 2022, ' Multivariate GWAS of psychiatric disorders and their cardinal symptoms reveal two dimensions of cross-cutting genetic liabilities ', Cell Genomics, vol. 2, no. 6, 100140, pp. 1-19 . https://doi.org/10.1016/j.xgen.2022.100140
Cell Genomics, 2(6):100140. Cell Press
Cell Genomics, 2(6):100140, 1-19. Cell Press

A single dimension of general psychopathology, p , has been hypothesized to represent a general liability that spans multiple types of psychiatric disorders and non-clinical variation in psychiatric symptoms across the lifespan. We conducted genome-w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a112183890f89a7eb35a32447782831
https://doi.org/10.1016/j.xgen.2022.100140

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Association between biological ageing and periodontitis: Evidence from a cross-sectional survey and multi-omics Mendelian randomization analysis.

Autor: Huang Z; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, China., Peng S; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, China., Cen T; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, China., Wang X; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, China.; Department of Periodontology, School & Hospital of Stomatology, Wuhan University, Wuhan, China., Ma L; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, China.; Department of Periodontology, School & Hospital of Stomatology, Wuhan University, Wuhan, China., Cao Z; State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, China.; Department of Periodontology, School & Hospital of Stomatology, Wuhan University, Wuhan, China.

Publikováno v: Journal of clinical periodontology [J Clin Periodontol] 2024 Oct; Vol. 51 (10), pp. 1369-1383. Date of Electronic Publication: 2024 Jul 02.

A Causal Relationship Between Type 1 Diabetes and Risk of Osteoporosis: A Univariable and Multivariable Mendelian Randomization Study.

Autor: Qin, Hailin¹ (AUTHOR), Yang, Kui² (AUTHOR), Wang, Hufei² (AUTHOR), Jiao, Wenyong² (AUTHOR)

Publikováno v: Journal of Diabetes Research. 5/8/2024, Vol. 2024, p1-6. 6p.

Unraveling the Relation Between Personality and Well-Being in a Genetically Informative Design.

Autor: Pelt, Dirk H. M.^1,2 (AUTHOR) h.m.pelt@vu.nl, de Vries, Lianne P.^1,2 (AUTHOR), Bartels, Meike^1,2 (AUTHOR)

Publikováno v: European Journal of Personality. Jan2024, Vol. 38 Issue 1, p99-119. 21p.