Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Linmeng Zhang"'
Autor:
Chen Yang, Senquan Zhang, Zhuoan Cheng, Zhicheng Liu, Linmeng Zhang, Kai Jiang, Haigang Geng, Ruolan Qian, Jun Wang, Xiaowen Huang, Mo Chen, Zhe Li, Wenxin Qin, Qiang Xia, Xiaonan Kang, Cun Wang, Hualian Hang
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-19 (2022)
Abstract Background Numerous studies have used multi-region sampling approaches to characterize intra-tumor heterogeneity (ITH) in hepatocellular carcinoma (HCC). However, conventional multi-region sampling strategies do not preserve the spatial deta
Externí odkaz:
https://doaj.org/article/d20961f1c7004cf0985792dab1e062f1
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/53456613f4de422ebc718486f40c8eb9
Autor:
Zhicheng Liu, Dongxu Lin, Yi Zhou, Linmeng Zhang, Chen Yang, Bin Guo, Feng Xia, Yan Li, Danyang Chen, Cun Wang, Zhong Chen, Chao Leng, Zhenyu Xiao
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract The emerging targeted therapies have revolutionized the treatment of advanced clear cell renal cell carcinoma (ccRCC) over the past 15 years. Nevertheless, lack of personalized treatment limits the development of effective clinical guideline
Externí odkaz:
https://doaj.org/article/1e79f9ce14e84209b837ffb649ece6ed
Autor:
Chunting Zeng, Linmeng Zhang, Chanhua Luo, Chen Yang, Xiaowen Huang, Linfeng Fan, Jiarong Li, Fengsheng Chen, Zelong Luo
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background A malignancy of the liver, hepatocellular carcinoma (HCC) is among the most common and second-leading causes of cancer-related deaths worldwide. A reliable prognosis model for guidance in choosing HCC therapies has yet to be estab
Externí odkaz:
https://doaj.org/article/b0072cae18d446d3a6d3e87cb8d5b5d2
Autor:
Yan Li, Chen Yang, Zhicheng Liu, Shangce Du, Susan Can, Hailin Zhang, Linmeng Zhang, Xiaowen Huang, Zhenyu Xiao, Xiaobo Li, Jingyuan Fang, Wenxin Qin, Chong Sun, Cun Wang, Jun Chen, Huimin Chen
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-16 (2022)
Abstract Background In recent years, the application of functional genetic immuno-oncology screens has showcased the striking ability to identify potential regulators engaged in tumor-immune interactions. Although these screens have yielded substanti
Externí odkaz:
https://doaj.org/article/5c4e9dcc453b4fe196b346340c7d3c5c
Autor:
Chen Yang, Hailin Zhang, Mengnuo Chen, Siying Wang, Ruolan Qian, Linmeng Zhang, Xiaowen Huang, Jun Wang, Zhicheng Liu, Wenxin Qin, Cun Wang, Hualian Hang, Hui Wang
Publikováno v:
eLife, Vol 11 (2022)
Pharmacologic perturbation projects, such as Connectivity Map (CMap) and Library of Integrated Network-based Cellular Signatures (LINCS), have produced many perturbed expression data, providing enormous opportunities for computational therapeutic dis
Externí odkaz:
https://doaj.org/article/2bf05f54ac574e679d0be89137dde479
Autor:
Haigang, Geng, Ruolan, Qian, Linmeng, Zhang, Chen, Yang, Xiang, Xia, Cun, Wang, Gang, Zhao, Zizhen, Zhang, Chunchao, Zhu
Publikováno v:
Aging. 14:6358-6376
Gastric cancer (GC) is one of the most aggressive malignant tumors worldwide. Ferroptosis is a kind of iron-dependent cell death, which is proved to be closely related to tumor progression. In this study, we aim at constructing a ferroptosis-related
Autor:
Linmeng Zhang, Chen Yang, Xiaowen Huang, Yuchen Guo, Wenxin Qin, Ruolan Qian, Xuhui Ma, Zhicheng Liu, Dayong Zhang, Jun Wang, Huimin Chen, Yiwen Huang, Cun Wang
Publikováno v:
Theranostics
Almost all the current therapies against liver cancer are based on the “one size fits all” principle and offer only limited survival benefit. Fortunately, synthetic lethality (SL) may provide an alternate route towards individualized therapy in l
Autor:
Haigang Geng, Zhongyi Dong, Linmeng Zhang, Chen Yang, Tingting Li, Yuxuan Lin, Shouyu Ke, Xiang Xia, Zizhen Zhang, Gang Zhao, Chunchao Zhu
Publikováno v:
Cancers; Volume 14; Issue 13; Pages: 3276
Helicobacter pylori (HP) infection is the greatest risk factor for gastric cancer (GC). Increasing evidence has clarified that tumor immune microenvironment (TIME) is closely related to the prognosis and therapeutic efficacy of HP-positive (HP+) GC p
Autor:
Shuo Hu, Yonglin Pang, Yong He, Yuan Yang, Henian Zhang, Linmeng Zhang, Beiyi Zheng, Caiyun Hu, Qing Wang
Publikováno v:
Processes; Volume 11; Issue 4; Pages: 1240
With the continuous enrichment of big data technology application scenarios, the clustering analysis of a data stream has become a research hotspot. However, the existing data stream clustering algorithms usually have some defects, such as inability