Zobrazeno 1 - 10
of 694
pro vyhledávání: '"Linlin Sun"'
Publikováno v:
Experimental Gerontology, Vol 194, Iss , Pp 112508- (2024)
hTERT gene therapies hold significant promise for treating age-related diseases. However, further research is required to address the challenges of delivery and ethical considerations. We hypothesized that exosomes derived from hTERT-immortalized cel
Externí odkaz:
https://doaj.org/article/e00b529ee77e48bdbf49fa8f1b135079
Autor:
Pusheng Quan, Xueying Li, Yao Si, Linlin Sun, Fei Fan Ding, Yuwei Fan, Han Liu, Chengqun Wei, Ruihua Li, Xue Zhao, Fan Yang, Lifen Yao
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract The pathogenesis of Parkinson’s disease (PD) is strongly associated with neuroinflammation, and type I interferons (IFN-I) play a crucial role in regulating immune and inflammatory responses. However, the specific features of IFN in differ
Externí odkaz:
https://doaj.org/article/2d63cc2e150a4904a85ffec48e386de5
Autor:
Linlin Sun, Bin Cao, Qingshuang Ma, Qiuzhi Gao, Jiahao Luo, Minglong Gong, Jing Bai, Huijun Li
Publikováno v:
Journal of Materials Research and Technology, Vol 29, Iss , Pp 656-667 (2024)
Developing materials with multiple desired characteristics is a tremendous challenge, particularly in an elaborate material system. Herein, a machine learning assisted material design strategy was applied to simultaneously optimize dual target attrib
Externí odkaz:
https://doaj.org/article/f9ac19a36d3f4ea08261b4d6136ca08b
Publikováno v:
PeerJ, Vol 12, p e17749 (2024)
Triple negative breast cancer (TNBC) as the most aggressive molecular subtype of breast cancer is characterized by high cancer cell proliferation and poor patient prognosis. Abnormal lipid metabolism contributes to the malignant process of cancers. S
Externí odkaz:
https://doaj.org/article/66c16c0dce264c8e836ac0e3f492a00c
Autor:
Xueying Li, Pusheng Quan, Yao Si, Fei Liu, Yuwei Fan, Feifan Ding, Lina Sun, Han Liu, Shuo Huang, Linlin Sun, Fan Yang, Lifen Yao
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-22 (2024)
Abstract Ferroptosis is an iron-dependent cell death mechanism involving the accumulation of lipid peroxides. As a critical regulator, glutathione peroxidase 4 (GPX4) has been demonstrated to be downregulated in epilepsy. However, the mechanism of fe
Externí odkaz:
https://doaj.org/article/2953c029bf244ce0a230e142c21a2716
Publikováno v:
Pifu-xingbing zhenliaoxue zazhi, Vol 30, Iss 6, Pp 518-523 (2023)
Objective To evaluate the efficacy and safety of trephine resection combined with fractional ablative CO2 laser for pitted acne scars. Methods Sixty eight patients with facial pitted acne scars were enrolled from the Medical Cosmetology Center of Zhe
Externí odkaz:
https://doaj.org/article/f4c3b19317ef438196cb62353b04ccdd
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionPeripheral sensory neurons serve as the initial responders to the external environment. How these neurons react to different sensory stimuli, such as mechanical or thermal forces applied to the skin, remains unclear.MethodsUsing in vivo t
Externí odkaz:
https://doaj.org/article/f3fdb7dc263248a7a6ebc035f7d2aab7
Publikováno v:
Heliyon, Vol 10, Iss 7, Pp e28921- (2024)
Background: Diabetic cardiomyopathy is one common cardiovascular complication without effective treatments. Dihydromyricetin (DHY), a natural dihydroflavonol compound extracted from Ampelopsis grossedentata, possesses versatile pharmacologically impo
Externí odkaz:
https://doaj.org/article/4251b725c4c44572bd04004ec8bfa0b3
Autor:
Hongjian Zhang, Shuai Fan, Zixu Chen, Xin Han, Linlin Sun, Jingwei Sun, Guangming Wang, Shenghui Fu, Chengfu Zhang, Jinxing Wang, Shuangxi Liu
Publikováno v:
Heliyon, Vol 10, Iss 6, Pp e28068- (2024)
In response to the problem of excessive power consumption during the furrowing operation of orchard furrowing fertilizer machines, an optimization experiment of furrowing operation parameters for orchard furrowing fertilizer machine was conducted bas
Externí odkaz:
https://doaj.org/article/34932a8d2526460799aab90d164582cd
Autor:
Qingshuang Ma, Xintong Li, Ruifeng Xin, Enyu Liu, Qiuzhi Gao, Linlin Sun, Xuming Zhang, Chengxian Zhang
Publikováno v:
Journal of Materials Research and Technology, Vol 26, Iss , Pp 4168-4178 (2023)
At present, the operating temperature of the fourth-generation of nickel-based powder superalloys has not reach the target of 815 °C, and the traditional superalloy design and optimization methods are costly and inefficient. To overcome these challe
Externí odkaz:
https://doaj.org/article/7725772c43c94dcbbed95667d4b11e8f