Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Linli La"'
Autor:
Xue Bai, Guiqin Liu, Jianxin Yang, Junbo Zhu, Qian Wang, Yang Zhou, Wenqi Gu, Linli La, Xiangyang Li
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT This study was conducted to investigate the effects of high-altitude hypoxic environments on the gut microbiota. Male Sprague-Dawley rats were randomly divided into three groups, namely, the plain, moderate-altitude hypoxic, and high-altitud
Externí odkaz:
https://doaj.org/article/960c3c8871d14ef09575d03cd01ef917
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Hypoxia, an essential feature of high-altitude environments, has a significant effect on drug metabolism. The hypoxia–gut microbiota–CYP450/drug transporter axis is emerging as a vital factor in drug metabolism. However, the mechanisms through wh
Externí odkaz:
https://doaj.org/article/51195b3be8ab4740bc353a3defce06e0
Autor:
Xiangyang Li, Yabin Duan, Xue Bai, Jun-Bo Zhu, Yang Zhou, Wenqi Gu, Jianxin Yang, Linli La, Guiqin Liu, Qian Wang
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 50(2)
Hypoxia is the main characteristic of a high-altitude environment, affect ing drug metabolism. However, so far, the mechanism of miRNA involved in the regulation of drug metabolism and transporters under high-altitude hypoxia is still unclear. This s
Autor:
Qian Wang, Jun-Bo Zhu, Xiangyang Li, Yabin Duan, Guiqin Liu, Wenqi Gu, Xue Bai, Linli La, Yang Zhou, Jianxin Yang
Publikováno v:
SSRN Electronic Journal.
Background: Hypoxia is the main characteristic of a high-altitude environment, affecting drug metabolism. However, little is known about the role of microRNA (miRNA) in drug metabolism under high-altitude hypoxia. This study aims to investigate the f