Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Linley E. Watson"'
Autor:
Linley E Watson, Shu-Ru Kuo, Khurshed Katki, Tongyun Dang, Seong Kyu Park, David E Dostal, Wei-Jen Tang, Stephen H Leppla, Arthur E Frankel
Publikováno v:
PLoS ONE, Vol 2, Iss 5, p e466 (2007)
Anthrax infections are frequently associated with severe and often irreversible hypotensive shock. The isolated toxic proteins of Bacillus anthracis produce a non-cytokine-mediated hypotension in rats by unknown mechanisms. These observations suggest
Externí odkaz:
https://doaj.org/article/5852b824721a42d18655ae1e0f2fc452
Publikováno v:
Frontiers in Bioscience. :922-927
The effects of aldosterone receptor blockade on echocardiography in spontaneously hypertensive rats (SHR) are not fully characterized. In this study, multiple echocardiographic parameters were compared for 42 weeks between SHR versus Wistar-Kyoto rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a109032ba007b0dc2732188a0bdba25
https://doi.org/10.2741/e671
https://doi.org/10.2741/e671
Autor:
Mani Chopra, David E. Dostal, Linley E. Watson, Honey B. Golden, Avadhesh C. Sharma, Padmalaya Das
Publikováno v:
Life Sciences. 87:672-678
We examined the effect of norepinephrine (NE) infusion on left ventricular function and apoptotic genes during progression of polymicrobial sepsis.Male Sprague-Dawley rats (350-400 g) were made septic by intraperitoneal (i.p.) administration of 200mg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c7e67594b3b87935e9ff0cae070491
https://doi.org/10.1016/j.lfs.2010.09.029
https://doi.org/10.1016/j.lfs.2010.09.029
Autor:
Manuela Smith, Guangrong Lu, Hind Lal, Donald M. Foster, David E. Dostal, Rakeshwar S. Guleria, Sandhya Sanghi, Linley E. Watson
Publikováno v:
Cardiovascular & Hematological Agents in Medicinal Chemistry. 5:109-132
Integrins are the principle mediators of molecular dialog between a cell and its extracellular matrix environment. The unique combinations of integrin subunits determine which extracellular matrix molecules are recognized by a cell. Recent studies ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abe0475e353c099aa78cf194300a08d
https://doi.org/10.2174/187152507780363223
https://doi.org/10.2174/187152507780363223
Autor:
Linley E. Watson, Coty W. Jewell, David E. Dostal, Sandhya Sanghi, Sheldon Chaffer, Peter J. Naus, Eric J. MacLaughlin
Publikováno v:
Cardiovascular & Hematological Disorders-Drug Targets. 6:83-98
Non-steroidal anti-inflammatory drugs (NSAIDs) represent a clinically important class of agents. NSAIDs are commonly used in treatment of conditions such as headache, fever, inflammation and joint pain. Complications often arise from chronic use of N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff01f0b21b0b0af64284ab06a057c6b
https://doi.org/10.2174/187152906777441803
https://doi.org/10.2174/187152906777441803
Publikováno v:
Cardiovascular & Hematological Agents in Medicinal Chemistry. 4:129-153
Aldosterone is a mineralocorticoid primarily produced in the zona glomerulosa of the adrenal gland. For many years, aldosterone (Aldo) was thought to have its sole site of action in the kidney, where it regulated sodium excretion and potassium reabso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eda9b4cf3a49348b114b7f21870b7bd
https://doi.org/10.2174/187152506776369935
https://doi.org/10.2174/187152506776369935
Publikováno v:
Journal of the American Society of Echocardiography. 17:161-167
Background Because of safety, repeatability, and portability, clinical echocardiography is well established as a standard for cardiac anatomy, cardiac function, and hemodynamics. Similarly, application of echocardiography in commonly used rat experim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67bd8e8749fbe0702e74075119f01f70
https://doi.org/10.1016/j.echo.2003.10.010
https://doi.org/10.1016/j.echo.2003.10.010
Autor:
David E. Dostal, Linley E. Watson
Publikováno v:
Hypertension. 47:830-832
Congestive heart failure (HF) is a frequent reason for hospital admission. Fifty percent of HF hospitalizations have normal ejection fraction (EF), 1 referred to as diastolic HF (DHF). In contrast, patients with systolic HF (SHF) have reduced EF. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0d8a1cdc4484ef90619ba2b773f6518
https://doi.org/10.1161/01.hyp.0000215591.63549.dc
https://doi.org/10.1161/01.hyp.0000215591.63549.dc
Autor:
Catherine J. McNeal, Mark W. Riggs, Bruce Palmer, Clinton E. Baisden, Mark E. Lawrence, Ronald D. Macfarlane, Linley E. Watson
Publikováno v:
Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 40:286-288
Background: Early studies have suggested that there may be differences in the concentration of lipoprotein particles and their associated apolipoproteins in arterial and venous blood and that this gradient might explain a proclivity to develop athero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b58ac6111e3e7e61763dbb98cbbf43d2
https://doi.org/10.1258/000456303321610637
https://doi.org/10.1258/000456303321610637
Publikováno v:
Circulation Research. 109
We previously identified the JNK-B56α-PP2A signaling axis as a major target in anthrax lethal toxin (LT)-induced cardiac dysfunction. Thus, we further tested whether LT-mediated loss in cardiac function is a consequence of dysregulated calcium handl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea67aab571ee1dbda25608ee03268a89
https://doi.org/10.1161/res.109.suppl_1.ap082
https://doi.org/10.1161/res.109.suppl_1.ap082