Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Linkang Cai"'
Autor:
Hongxia Su, Hui Geng, Linkang Cai, Minjie Xu, Wenpin Xing, Wei Long, Biao Liu, Yankun Li, Binlei Liu
Publikováno v:
Cancer Medicine, Vol 12, Iss 12, Pp 13573-13585 (2023)
Abstract Objective In order to ensure the stable transcription of target genes, we constructed a eukaryotic high expression vector carrying an immune‐check inhibitor PD‐1v and a variety of cytokines, and studied their effects on activating immune
Externí odkaz:
https://doaj.org/article/3d69cfa1dd04457a861951b9fb6efe64
Autor:
Han Hu, Siqi Zhang, Linkang Cai, Haixiao Duan, Yuying Li, Junhan Yang, Yang Wang, Biao Liu, Shuang Dong, Zhizheng Fang, Binlei Liu
Publikováno v:
Virology Journal, Vol 19, Iss 1, Pp 1-12 (2022)
Abstract Background Selectively replicating herpes simplex virus-2 (HSV-2) vector is a promising treatment for cancer therapy. The insertion of multiple transgenes into the viral genome has been performed to improve its oncolytic activity. Methods He
Externí odkaz:
https://doaj.org/article/ba82300fc066418e99332913e5aa8487
Autor:
Biao Liu, Peng Ni, Linkang Cai, Xiaotai Shi, Shuaijie Ji, Zonghuang Ke, Siqi Zhang, Bing Hu, Binfeng Yang, Yiyan Xu, Wei Long, Zhizheng Fang, Han Hu, Yang Wang, Wen Zhang, Hui Geng, Yan. Xu, Xiaodi Zheng, Zhong Wang, Baoqian Zhang, Kai Pan, Kangping Zhou, Yanfang Cui, Hanming Wang, Binlei Liu
A novel uncapped mRNA platform was developed. Five lipid nanoparticle (LNP)-encapsulated mRNA constructs were made to evaluate several aspects of our platform, including transfection efficiency and durability in vitro and in vivo and the activation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62a30483bb64ff0b65ac1fea6fa9e477
https://doi.org/10.1101/2022.06.05.494796
https://doi.org/10.1101/2022.06.05.494796
Autor:
Jing Jin, Runyang Wang, Junhan Yang, Han Hu, Di Wang, Linkang Cai, Zhizheng Fang, Shuang Dong, Sheng Hu, Yang Wang, Binlei Liu
Publikováno v:
Hum Gene Ther
BsAb (bispecific antibody)-armed oncolytic viruses (OVs) are effective in regulating tumor microenvironment. However, oHSV2 (oncolytic herpes simplex virus type 2) expressing immune checkpoints targeting BsAb molecules are not reported. Here, we gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243754e823c38764397de592a8565377
https://europepmc.org/articles/PMC9242723/
https://europepmc.org/articles/PMC9242723/
Autor:
Yanyan, Cao, Fu, Xiong, Xuefeng, Kan, Xiaopeng, Guo, Tao, Ouyang, Runyang, Wang, Junhan, Yang, Linkang, Cai, Binlei, Liu, Bin, Liang, Chuansheng, Zheng
Publikováno v:
Pharmacological Research. 187:106581
To investigate the mechanism and efficacy of transarterial viroembolization (TAVE) with an oncolytic virus (OH2) for the treatment of liver cancer in rabbit VX2 tumor models.Subcutaneous tumor and liver cancer models were established to determine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a4b510a47163e238c198bcae08f4cf
https://doi.org/10.1016/j.phrs.2022.106581
https://doi.org/10.1016/j.phrs.2022.106581
Autor:
Jing Jin, Runyang Wang, Junhan Yang, Han Hu, Di Wang, Linkang Cai, Zhizheng Fang, Shuang Dong, Shen Hu, Yang Wang, Binlei Liu
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6788401f16a8239683c2b4962e7c2c13
https://doi.org/10.2139/ssrn.3941808
https://doi.org/10.2139/ssrn.3941808