Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Linka Xie"'
Publikováno v:
Genes; Volume 13; Issue 12; Pages: 2281
Pyroptosis is an inflammatory form of programmed necrotic cell death, but its potential prognostic value in acute myeloid leukemia (AML) remains unclear. On the basis of available AML data from TCGA and TARGET databases, a 10-gene signature model was
Autor:
Qian Guo, Feng Li, Zhong Fang, Renpeng Peng, Yimin Dong, Jai Wang, Hanfeng Guan, Kehan Song, Honglei Kang, Linka Xie
Publikováno v:
Spine. 46(22)
STUDY DESIGN Retrospective analysis. OBJECTIVE The aim of this study was to develop and validate a competing-risk-based prognostic model and a nomogram for predicting the three- and five-year probability of cancer-specific death (CSD) in patients wit
Autor:
Chunmei Ye, Juan Pan, Cuiwei Liu, Gang Wu, Yuxi Ma, Jieying Zhang, Sheng Zhou, Zihan Xia, Chong Lu, Yanxia Zhao, Tao Liu, Linka Xie, Ting Hu
Publikováno v:
Aging (Albany NY)
The angiotensin II type I receptor (AGTR1) has a strong influence on tumor growth, angiogenesis, inflammation and immunity. However, the role of AGTR1 on lymph node metastasis (LNM) in breast cancer, which correlates with tumor progression and patien
Publikováno v:
Oncotarget
Although Hodgkin and Reed-Sternberg (HRS) cells of classical Hodgkin lymphoma (cHL) derived from germinal or post germinal B cells, they have lost the B cell phenotype in the process of lymphomagenesis. The phenomenon can be at least partially explai
Autor:
Martin Braddock, Gui-Long Guo, Gui-Qi Zhu, Linka Xie, Zonghai Huang, Ouchen Wang, Liang Shi, Wen-Yue Liu, Ming-Hua Zheng, Jie You
Publikováno v:
Oncotarget
// Jie You 1, 2, * , Gui-Qi Zhu 3, 4, * , Linka Xie 5, * , Wen-Yue Liu 6 , Liang Shi 7 , Ou-Chen Wang 1 , Zong-Hai Huang 2 , Martin Braddock 8 , Gui-Long Guo 1 , Ming-Hua Zheng 3, 9 1 Department of Oncological Surgery, The First Affiliated Hospital o
Autor:
Marion J. Vogel, Alexey Ushmorov, Thomas Wirth, Clarissa D. Osswald, Franziska Gehringer, Christian Steidl, Hanfeng Guan, Fong Chun Chan, Franziska Herrmann, Sarah M. Pick, Linka Xie
Publikováno v:
Blood. 131(14)
We recently found that FOXO1 repression contributes to the oncogenic program of classical Hodgkin lymphoma (cHL). Interestingly, FOXO3A, another member of the FOXO family, was reported to be expressed in the malignant Hodgkin and Reed-Sternberg cells
Autor:
Johanna Färbinger, Hanfeng Guan, Thomas Wirth, Marion J. Vogel, Frank Leithäuser, Olga Ritz, Karlheinz Holzmann, Clarissa D. Weitzer, Alexey Ushmorov, Linka Xie, Peter Möller, Franziska Gehringer, Silke Brüderlein
Publikováno v:
Oncotarget
// Linka Xie 1,2,* , Olga Ritz 3,* , Frank Leithauser 3 , Hanfeng Guan 2,4 , Johanna Farbinger 2 , Clarissa D Weitzer 2 , Franziska Gehringer 2 , Silke Bruderlein 3 , Karlheinz Holzmann 5 , Marion J. Vogel 2 , Peter Moller 3 , Thomas Wirth 2 and Alex
Publikováno v:
The Journal of Pathology. 229:775-783
Burkitt lymphoma (BL) is caused by translocation of the MYC gene to an immunoglobulin locus resulting in its constitutive expression depending on the activity of the immunoglobulin (Ig) enhancer elements. Treatment of BL cell lines with epigenetic mo
Autor:
Peter Möller, Johanna Färbinger, Christin Pelzer, Harald J. Maier, Frank Leithäuser, Christian Steidl, Linka Xie, Hanfeng Guan, Alexey Ushmorov, Randy D. Gascoyne, Thomas Wirth, Marion J. Vogel
Publikováno v:
Blood. 119:3503-3511
The FOXO transcription factors control proliferation and apoptosis in different cell types. Their activity is regulated by posttranslational modifications, mainly by the PI3K-PKB pathway, which controls nuclear export and degradation. We show that FO
Autor:
Lucia Flossbach, Hanfeng Guan, Linka Xie, Frank Leithäuser, Peter Möller, Alexey Ushmorov, Thomas Wirth
Publikováno v:
Blood. 116:1469-1478
The transcription factor KLF4 may act both as an oncogene and a tumor suppressor in a tissue-depending manner. In T- and pre-B-cell lymphoma, KLF4 was found to act as tumor suppressor. We found the KLF4 promoter methylated in B-cell lymphoma cell lin