Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Linjun, You"'
Autor:
Chen Wang, Jiaping Ni, Dongqing Zhai, Yanchao Xu, Zijie Wu, Yuyuan Chen, Ning Liu, Juan Du, Yumeng Shen, Guilai Liu, Yong Yang, Linjun You, Weiwei Hu
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 5, Pp 1150-1163 (2024)
Abstract Hepatocellular carcinoma (HCC) is associated with a poor prognosis. Our previous study demonstrated that Pleomorphic adenoma gene like-2 (PLAGL2) was a potential therapeutic target in HCC. However, the mechanisms that lead to the upregulatio
Externí odkaz:
https://doaj.org/article/23073bf205194891b14ec7db47f93832
Autor:
Shuang Feng, Duowei Wang, Yanyan Jin, Shi Huang, Tong Liang, Wei Sun, Xiuli Du, Luoyi Zhuo, Chun Shan, Wenbo Zhang, Tian Jing, Sen Zhao, Ruisi Hong, Linjun You, Guilai Liu, Leilei Chen, Dan Ye, Xianjing Li, Yong Yang
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114300- (2024)
Summary: The high infiltration of tumor-associated macrophages (TAMs) in the immunosuppressive tumor microenvironment prominently attenuates the efficacy of immune checkpoint blockade (ICB) therapies, yet the underlying mechanisms are not fully under
Externí odkaz:
https://doaj.org/article/0f7b7fe2af564dcd8175811f38494691
Autor:
Hanyu Yang, Linjun You, Zhongyan Wang, Lu Yang, Xun Wang, Wenhan Wu, Hao Zhi, Guangmei Rong, Yun Sheng, Xiaodong Liu, Li Liu
Publikováno v:
Redox Biology, Vol 69, Iss , Pp 103019- (2024)
Hepatic encephalopathy (HE) is often associated with endogenous serotonin (5-HT) disorders. However, the reason for elevated brain 5-HT levels due to liver failure remains unclear. This study aimed to investigate the mechanism by which liver failure
Externí odkaz:
https://doaj.org/article/0c06584611374d1fa409fbb2d695fb77
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 104 (2023)
Background: The tumor immune microenvironment (TIME) of adrenocortical carcinoma (ACC) is heterogeneous. However, a classification of ACC based on the TIME remains unexplored. Methods: We hierarchically clustered ACC based on the enrichment levels of
Externí odkaz:
https://doaj.org/article/015a8e5958514d1aac25597a296c496e
Autor:
Zhuhui Chen, Yue Xiong, Ranran Ma, Pei Chen, Le Duan, Shuying Yang, Ineza Urujeni Gisèle, Linjun You, Deli Xiao
Publikováno v:
New Journal of Chemistry. 47:7862-7872
Among the three pre-treatment materials, Fe3O4@HPMC@DMSA NPs were selected to be the best material and were used to perform MSPE-HPLC-UV.
Autor:
Yong Yang, Qingyi Zhu, Jin-Rong Zhou, Jinsong Bian, Weiyan Tao, Yan Cheng, Jingjing Duan, Xiaofang Gao, Wanli Ye, Shijia Du, Xianjing Li, Zhuo Wang, Zhen Chen, Guangjiang Shi, Zhili Zhao, Yan Li, Linjun You, Hongxi Wu
Disruption of IRF8 in PCa cells affects cell growth in vitro and tumorigenesis in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c8ae95d749b67c0638945ef3d73ad24
https://doi.org/10.1158/0008-5472.22424616
https://doi.org/10.1158/0008-5472.22424616
Autor:
Yong Yang, Qingyi Zhu, Jin-Rong Zhou, Jinsong Bian, Weiyan Tao, Yan Cheng, Jingjing Duan, Xiaofang Gao, Wanli Ye, Shijia Du, Xianjing Li, Zhuo Wang, Zhen Chen, Guangjiang Shi, Zhili Zhao, Yan Li, Linjun You, Hongxi Wu
IRF8 was not frequently mutated and methylated in clinical PCa tissues and cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60d01c2e654ccce805b4d90bd8e752f0
https://doi.org/10.1158/0008-5472.22424598.v1
https://doi.org/10.1158/0008-5472.22424598.v1
Autor:
Yong Yang, Qingyi Zhu, Jin-Rong Zhou, Jinsong Bian, Weiyan Tao, Yan Cheng, Jingjing Duan, Xiaofang Gao, Wanli Ye, Shijia Du, Xianjing Li, Zhuo Wang, Zhen Chen, Guangjiang Shi, Zhili Zhao, Yan Li, Linjun You, Hongxi Wu
In incurable castration-resistant prostate cancer (CRPC), resistance to the novel androgen receptor (AR) antagonist enzalutamide is driven mainly by AR overexpression. Here we report that the expression of interferon regulatory factor 8 (IRF8) is inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e886effb330b35da8ff4d89921debbc0
https://doi.org/10.1158/0008-5472.c.6511821.v1
https://doi.org/10.1158/0008-5472.c.6511821.v1
Autor:
Wenguang Wang, Xingli Wang, Feng Tao, Kaiyuan Hu, Junying Zhang, Jinhui Wu, Linjun You, Weijun Zhao
Publikováno v:
Molecular pharmaceutics. 19(11)
The efficacy of radiotherapy is significantly constricted by tumor hypoxia. To overcome this obstacle, one promising approach is to use the perfluorocarbon-based O
Autor:
Chao Qin, Linjun You, Chunyong Wu, Jungen Chen, Xinran Li, Junying Zhang, Yiling Ruan, Yueyue Shen, Yaozuo Yuan, Lifeng Kang
Publikováno v:
Molecular Pharmaceutics. 18:2198-2207
Growing evidence has shown that some pharmaceutical excipients can act on drug transporters. The present study was aimed at investigating the effects of 13 commonly used excipients on the intestinal absorption of metformin (MTF) and the underlying me