Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Linjing, Mu"'
Autor:
Jie Wang, Yingfang He, Xing Chen, Lin Huang, Junpeng Li, Zhiwen You, Qi Huang, Shuhua Ren, Kun He, Roger Schibli, Linjing Mu, Yihui Guan, Qihao Guo, Jun Zhao, Fang Xie
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Metabotropic glutamate receptor 5 (mGluR5) is involved in regulating integrative brain function and synaptic transmission. Aberrant mGluR5 signaling and relevant synaptic failure play a key role in the initial pathophysiological m
Externí odkaz:
https://doaj.org/article/3a9dfe62d12145639ac45c3fb9d29f84
Reducing kidney uptake of radiolabelled exendin-4 using variants of the renally cleavable linker MVK
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 8, Iss 1, Pp 1-11 (2023)
Abstract Background Peptidic radiotracers are preferentially excreted through the kidneys, which often results in high persistent renal retention of radioactivity, limiting or even preventing therapeutic clinical translation of these radiotracers. Ex
Externí odkaz:
https://doaj.org/article/7cb71b70223b4ad48a286de080938fb3
Autor:
Ruiqing Ni, Nadja Straumann, Serana Fazio, Xose Luis Dean-Ben, Georgios Louloudis, Claudia Keller, Daniel Razansky, Simon Ametamey, Linjing Mu, César Nombela-Arrieta, Jan Klohs
Publikováno v:
Photoacoustics, Vol 32, Iss , Pp 100532- (2023)
Emerging evidence indicates crosstalk between the brain and hematopoietic system following cerebral ischemia. Here, we investigated metabolism and oxygenation in the spleen and spinal cord in a transient middle cerebral artery occlusion (tMCAO) model
Externí odkaz:
https://doaj.org/article/3965b1b689934382ac6f2fa77a2e5d10
Autor:
Débora E. Peretti, Federica Ribaldi, Max Scheffler, Linjing Mu, Valerie Treyer, Anton F. Gietl, Christoph Hock, Giovanni B. Frisoni, Valentina Garibotto
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundThe ATN model represents a research framework used to describe in subjects the presence or absence of Alzheimer’s disease (AD) pathology through biomarkers. The aim of this study was to describe the prevalence of different ATN profiles us
Externí odkaz:
https://doaj.org/article/ffa89413a5fa4806bb1cafeefb615179
Autor:
Vasil Kecheliev, Francesco Spinelli, Adrienne Herde, Ahmed Haider, Linjing Mu, Jan Klohs, Simon M. Ametamey, Ruiqing Ni
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Neuroinflammation plays an important role in the pathophysiology of Alzheimer’s disease. The cannabinoid type 2 receptor (CB2R) is an emerging target for neuroinflammation and therapeutics of Alzheimer’s disease. Here, we aim to assess the altera
Externí odkaz:
https://doaj.org/article/188f49f4cba045b28e831825027dbe1d
Autor:
Linjing Mu, Stefanie D. Kramer, Hazem Ahmed, Stefan Gruber, Susanne Geistlich, Roger Schibli, Simon M. Ametamey
Publikováno v:
CHIMIA, Vol 74, Iss 12, Pp 960-967 (2020)
Radiopharmacy at ETH has worked on the development of novel PET tracers for neuro-, cardiac- and tumor imaging for many years. In this paper, our efforts on targeting the glutamatergic system of the metabotropic glutamate receptor subtype 5 (mGluR5)
Externí odkaz:
https://doaj.org/article/71673d550f23497586a85da8a9df44b4
Autor:
Linjing Mu, Stefanie D. Krämer, Geoffrey I. Warnock, Ahmed Haider, Susan Bengs, Giovanni Cartolano, Dominic S. Bräm, Claudia Keller, Roger Schibli, Simon M. Ametamey, Philipp A. Kaufmann, Catherine Gebhard
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract Purpose Clinical positron emission tomography (PET) imaging of the presynaptic norepinephrine transporter (NET) function provides valuable diagnostic information on sympathetic outflow and neuronal status. As data on the NET-targeting PET tr
Externí odkaz:
https://doaj.org/article/a60c235670a0490c944eea8ec4994051
Autor:
Bert-Ram Sah, Michael Sommerauer, Linjing Mu, Gloria Pla Gonzalez, Susanne Geistlich, Valerie Treyer, Roger Schibli, Alfred Buck, Geoffrey Warnock, Simon M. Ametamey
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-6 (2019)
Abstract Purpose (E)-3-(pyridin-2-ylethynyl)cyclohex-2-enone O-(3-(2-[18F]-fluoroethoxy)propyl) oxime ([18F]-PSS232) is a new PET tracer for imaging of metabotropic glutamate receptor subtype 5 (mGlu5), and has shown promising results in rodents and
Externí odkaz:
https://doaj.org/article/25e65f188ff04962924eeba6d01738bc
Autor:
Melanie Zechner, Claudia A. Castro Jaramillo, Nadine S. Zubler, Marco F. Taddio, Linjing Mu, Karl-Heinz Altmann, Stefanie D. Krämer
Publikováno v:
Journal of Medicinal Chemistry. 66:6782-6797
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b71a327139077f14792521f40d7b02b
https://doi.org/10.1021/acs.jmedchem.3c00168
https://doi.org/10.1021/acs.jmedchem.3c00168
Autor:
Susan Bengs, Geoffrey I. Warnock, Angela Portmann, Nidaa Mikail, Alexia Rossi, Hazem Ahmed, Dominik Etter, Valerie Treyer, Livio Gisler, Stefanie K. Pfister, Caitlin V. M. L. Jie, Alexander Meisel, Claudia Keller, Steven H. Liang, Roger Schibli, Linjing Mu, Ronny R. Buechel, Philipp A. Kaufmann, Simon M. Ametamey, Catherine Gebhard, Ahmed Haider
Publikováno v:
Journal of Nuclear Cardiology, 30 (1)
Background Myocardial perfusion imaging by positron emission tomography (PET-MPI) is the current gold standard for quantification of myocardial blood flow. F-18-flurpiridaz was recently introduced as a valid alternative to currently used PET-MPI prob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc710a86a46ebc2002d3b657363c251
https://doi.org/10.1007/s12350-022-02968-9
https://doi.org/10.1007/s12350-022-02968-9